Validation of human microRNA target pathways enables evaluation of target prediction tools

Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients

(2020) Tobias Fehlmann et al.   JAMA Oncology

miRSwitch: detecting microRNA arm shift and switch events

(2020) Fabian Kern et al.   NUCLEIC ACIDS RESEARCH

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling

(2019) Martin Hart et al.   Cell Death & Disease

MirGeneDB 2.0: the metazoan microRNA complement

(2019) Bastian Fromm et al.   NUCLEIC ACIDS RESEARCH

miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database

(2019) Tim Kehl et al.   NUCLEIC ACIDS RESEARCH

What’s the target: understanding two decades of in silico microRNA-target prediction

(2019) Fabian Kern et al.   BRIEFINGS IN BIOINFORMATICS

The biochemical basis of microRNA targeting efficacy

(2019) Sean E. McGeary et al.   SCIENCE

Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease

(2018) Mahsa Rostamian Delavar et al.   GENE

Modulation of intracellular calcium signaling by microRNA-34a-5p

(2018) Caroline Diener et al.   Cell Death & Disease

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

microRNAs in Parkinson’s Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches

(2017) Loredana Leggio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice

(2017) Ina Tesseur et al.   JOURNAL OF NEUROSCIENCE

Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo

(2017) Kirsty J. McMillan et al.   MOLECULAR THERAPY

The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster

(2017) Sabrina Pichler et al.   NEUROBIOLOGY OF AGING

mirDIP 4.1—integrative database of human microRNA target predictions

(2017) Tomas Tokar et al.   NUCLEIC ACIDS RESEARCH

miRCarta: a central repository for collecting miRNA candidates

(2017) Christina Backes et al.   NUCLEIC ACIDS RESEARCH

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions

(2017) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

Identification of targets of tumor suppressor microRNA-34a using a reporter library system

(2017) Yoshiaki Ito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving microRNA target prediction by modeling with unambiguously identified microRNA-target pairs from CLIP-ligation studies

(2016) Xiaowei Wang   BIOINFORMATICS

Multi-omics enrichment analysis using the GeneTrail2 web service

(2016) Daniel Stöckel et al.   BIOINFORMATICS

Specific miRNA Disease Biomarkers in Blood, Serum and Plasma: Challenges and Prospects

(2016) Christina Backes et al.   Molecular Diagnosis & Therapy

miRPathDB: a new dictionary on microRNAs and target pathways

(2016) Christina Backes et al.   NUCLEIC ACIDS RESEARCH

Distribution of miRNA expression across human tissues

(2016) Nicole Ludwig et al.   NUCLEIC ACIDS RESEARCH

Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus

(2016) Roman Tatura et al.   PARKINSONISM & RELATED DISORDERS

Identification of miR-34a-target interactions by a combined network based and experimental approach

(2016) Martin Hart et al.   Oncotarget

microRNA Profiles in Parkinson's Disease Prefrontal Cortex

(2016) Andrew G. Hoss et al.   Frontiers in Aging Neuroscience

Schisandrin B shows neuroprotective effect in 6-OHDA-induced Parkinson’s disease via inhibiting the negative modulation of miR-34a on Nrf2 pathway

(2015) Qinghua Ba et al.   BIOMEDICINE & PHARMACOTHERAPY

Midbrain dopamine neurons in Parkinson׳s disease exhibit a dysregulated miRNA and target-gene network

(2015) Christine E. Briggs et al.   BRAIN RESEARCH

miRWalk2.0: a comprehensive atlas of microRNA-target interactions

(2015) Harsh Dweep et al.   NATURE METHODS

Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

(2015) Begum Alural et al.   Frontiers in Cellular Neuroscience

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Roles for the TGFβ Superfamily in the Development and Survival of Midbrain Dopaminergic Neurons

(2014) Shane V. Hegarty et al.   MOLECULAR NEUROBIOLOGY

3′LIFE: a functional assay to detect miRNA targets in high-throughput

(2014) Justin M. Wolter et al.   NUCLEIC ACIDS RESEARCH

DoRiNA 2.0—upgrading the doRiNA database of RNA interactions in post-transcriptional regulation

(2014) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

(2013) Jeffrey H. Kordower et al.   BRAIN

miRmap web: comprehensive microRNA target prediction online

(2013) Charles E. Vejnar et al.   NUCLEIC ACIDS RESEARCH

A blood based 12-miRNA signature of Alzheimer disease patients

(2013) Petra Leidinger et al.   GENOME BIOLOGY

Interactive exploration of RNA22 microRNA target predictions

(2012) Phillipe Loher et al.   BIOINFORMATICS

Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line

(2011) Diana Scholz et al.   JOURNAL OF NEUROCHEMISTRY

Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System

(2011) Sara L. Montgomery et al.   Journal of Neuroimmune Pharmacology

Toward the blood-borne miRNome of human diseases

(2011) Andreas Keller et al.   NATURE METHODS

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DIANA-microT Web server upgrade supports Fly and Worm miRNA target prediction and bibliographic miRNA to disease association

(2011) M. Maragkakis et al.   NUCLEIC ACIDS RESEARCH

Class prediction for high-dimensional class-imbalanced data

(2010) Rok Blagus et al.   BMC BIOINFORMATICS

Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153

(2010) Epaminondas Doxakis   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide Dissection of MicroRNA Functions and Cotargeting Networks Using Gene Set Signatures

(2010) John S. Tsang et al.   MOLECULAR CELL

A dictionary on microRNAs and their putative target pathways

(2010) Christina Backes et al.   NUCLEIC ACIDS RESEARCH

Problems associated with reporter assays in RNAi studies

(2010) Guihua Sun et al.   RNA Biology

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

(2010) F. Moretti et al.   RNA

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

Understanding and using sensitivity, specificity and predictive values

(2009) Rajul Parikh et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Repression of  -synuclein expression and toxicity by microRNA-7

(2009) E. Junn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental validation of miRNA targets

(2007) Donald E. Kuhn et al.   METHODS