Functional Atlas of Primary miRNA Maturation by the Microprocessor

Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA

(2020) Alexander C. Partin et al.   MOLECULAR CELL

Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

(2020) Shaohua Li et al.   Nature Communications

RNA structure maps across mammalian cellular compartments

(2019) Lei Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Perspectives on targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine

(2019) Matthew D. Disney   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

EternaBrain: Automated RNA design through move sets and strategies from an Internet-scale RNA videogame

(2019) Rohan V. Koodli et al.   PLoS Computational Biology

Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing

(2018) Anthony M. Mustoe et al.   CELL

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Molecular Basis for the Single-Nucleotide Precision of Primary microRNA Processing

(2018) S. Chul Kwon et al.   MOLECULAR CELL

Novel determinants of mammalian primary microRNA processing revealed by systematic evaluation of hairpin-containing transcripts and human genetic variation

(2017) Christine Roden et al.   GENOME RESEARCH

RNase III nucleases from diverse kingdoms serve as antiviral effectors

(2017) Lauren C. Aguado et al.   NATURE

Emerging roles of DROSHA beyond primary microRNA processing

(2017) Dooyoung Lee et al.   RNA Biology

Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs

(2017) Alexander C. Partin et al.   Nature Communications

Structure of Human DROSHA

(2016) S. Chul Kwon et al.   CELL

Functional Anatomy of the Human Microprocessor

(2015) Tuan Anh Nguyen et al.   CELL

The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes

(2015) Wenwen Fang et al.   MOLECULAR CELL

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

(2014) Nathan A Siegfried et al.   NATURE METHODS

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Processing of microRNA primary transcripts requires heme in mammalian cells

(2014) Sara H. Weitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin

(2014) Jen Quick-Cleveland et al.   Cell Reports

Microprocessor Activity Controls Differential miRNA Biogenesis In Vivo

(2014) Thomas Conrad et al.   Cell Reports

Beyond Secondary Structure: Primary-Sequence Determinants License Pri-miRNA Hairpins for Processing

(2013) Vincent C. Auyeung et al.   CELL

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Lower and upper stem-single-stranded RNA junctions together determine the Drosha cleavage site

(2013) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fingerprinting Noncanonical and Tertiary RNA Structures by Differential SHAPE Reactivity

(2012) Kady-Ann Steen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Mechanisms of RNA SHAPE Chemistry

(2012) Jennifer L. McGinnis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Automated 3D structure composition for large RNAs

(2012) Mariusz Popenda et al.   NUCLEIC ACIDS RESEARCH

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosha processing controls the specificity and efficiency of global microRNA expression

(2011) Yong Feng et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

RNAstructure: software for RNA secondary structure prediction and analysis

(2010) Jessica S Reuter et al.   BMC BIOINFORMATICS

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

VARNA: Interactive drawing and editing of the RNA secondary structure

(2009) Kévin Darty et al.   BIOINFORMATICS