Mechanistic decoupling of exonuclease III multifunctionality into AP endonuclease and exonuclease activities at the single-residue level

The mechanism of gap creation by a multifunctional nuclease during base excision repair

(2021) Jungmin Yoo et al.   Science Advances

Base excision repair pathways of bacteria: new promise for an old problem

(2020) Krishna Kurthkoti et al.   Future Medicinal Chemistry

APEX1 is a novel diagnostic and prognostic biomarker for hepatocellular carcinoma

(2020) Lei Cao et al.   Aging-US

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Systematic Probing of the Sequence Selectivity of Exonuclease III with a Photosensitization Colorimetric Assay

(2019) Yu Ding et al.   ACS Omega

Molecular snapshots of APE1 proofreading mismatches and removing DNA damage

(2018) Amy M. Whitaker et al.   Nature Communications

Occurrence and stability of lone pair–π stacking interactions between ribose and nucleobases in functional RNAs

(2017) Mohit Chawla et al.   NUCLEIC ACIDS RESEARCH

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA

(2016) Modesto Redrejo-Rodríguez et al.   BIOCHIMIE

Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker

(2016) Sunga Choi et al.   DISEASE MARKERS

Critical determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3′–5′ exonuclease III

(2015) Taran Khanam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Capturing snapshots of APE1 processing DNA damage

(2015) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer

(2015) Yi Qing et al.   Drug Design Development and Therapy

Capturing snapshots of APE1 processing DNA damage

(2015) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

APE1/Ref-1 as a Serological Biomarker for the Detection of Bladder Cancer

(2015) Ju Hyun Shin et al.   Cancer Research and Treatment

Prognostic Value of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) Expression in Breast Cancer

(2014) Joohyun Woo et al.   PLoS One

Site-specific N-terminal labeling of proteins using sortase-mediated reactions

(2013) Christopher S Theile et al.   Nature Protocols

Recognition and processing of double-stranded DNA by ExoX, a distributive 3′–5′ exonuclease

(2013) Tianyu Wang et al.   NUCLEIC ACIDS RESEARCH

Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease

(2012) G. Lee et al.   SCIENCE

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

(2011) Jillian Orans et al.   CELL

Specialization of an Exonuclease III family enzyme in the repair of 3′ DNA lesions during base excision repair in the human pathogen Neisseria meningitidis

(2011) Jan Silhan et al.   NUCLEIC ACIDS RESEARCH

Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer

(2010) Rachel Abbotts et al.   CANCER TREATMENT REVIEWS

Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA

(2010) Kristina Lakomek et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Nucleases: diversity of structure, function and mechanism

(2010) Wei Yang   QUARTERLY REVIEWS OF BIOPHYSICS

Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA

(2009) S. Myong et al.   SCIENCE

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS