Molecular snapshots of APE1 proofreading mismatches and removing DNA damage

Base excision repair of oxidative DNA damage from mechanism to disease

(2017) Bret D Freudenthal   Frontiers in Bioscience-Landmark

Oxidized nucleotide insertion by pol β confounds ligation during base excision repair

(2017) Melike Çağlayan et al.   Nature Communications

Effects of mono- and divalent metal ions on DNA binding and catalysis of human apurinic/apyrimidinic endonuclease 1

(2016) Anastasia D. Miroshnikova et al.   Molecular BioSystems

APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress

(2016) Bret D. Wallace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control

(2016) Jekaterina Vohhodina et al.   Wiley Interdisciplinary Reviews-RNA

Capturing snapshots of APE1 processing DNA damage

(2015) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative characterization of protein–protein complexes involved in base excision DNA repair

(2015) Nina A. Moor et al.   NUCLEIC ACIDS RESEARCH

Capturing snapshots of APE1 processing DNA damage

(2015) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-Resolution Crystal Structures Reveal Plasticity in the Metal Binding Site of Apurinic/Apyrimidinic Endonuclease I

(2014) Hongzhen He et al.   BIOCHEMISTRY

Recognition and repair of chemically heterogeneous structures at DNA ends

(2014) Sara N. Andres et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

(2014) Bret D. Freudenthal et al.   NATURE

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

(2013) J. Willis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases

(2013) A. Mazouzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Characterization of the Endoribonuclease Active Site of Human Apurinic/Apyrimidinic Endonuclease 1

(2011) Wan-Cheol Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Substrate Channeling in Mammalian Base Excision Repair Pathways: Passing the Baton

(2010) Rajendra Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

(2009) Tong Zhou et al.   DNA REPAIR

Intrusion of a DNA Repair Protein in the RNome World: Is This the Beginning of a New Era?

(2009) G. Tell et al.   MOLECULAR AND CELLULAR BIOLOGY

Impairment of APE1 Function Enhances Cellular Sensitivity to Clinically Relevant Alkylators and Antimetabolites

(2009) D. R. McNeill et al.   MOLECULAR CANCER RESEARCH

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

(2009) T. Barnes et al.   NUCLEIC ACIDS RESEARCH

Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate†

(2008) Sophia T. Mundle et al.   BIOCHEMISTRY

Characterization of Mg2+Binding to the DNA Repair Protein Apurinic/Apyrimidic Endonuclease 1 via Solid-State25Mg NMR Spectroscopy

(2008) A. S. Lipton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY