Base excision repair pathways of bacteria: new promise for an old problem

Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision

(2019) Woo-Chan Ahn et al.   Nature Chemical Biology

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

(2018) Aigerim Turgimbayeva et al.   PLoS One

HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA

(2018) Kareem N. Mohni et al.   CELL

A non-canonical mismatch repair pathway in prokaryotes

(2017) A. Castañeda-García et al.   Nature Communications

Biochemical and structural characterization of DNA ligases from bacteria and archaea

(2016) G. Pergolizzi et al.   BIOSCIENCE REPORTS

A history of the DNA repair and mutagenesis field

(2016) Errol C. Friedberg   DNA REPAIR

Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1)

(2015) Nathan Donley et al.   ACS Chemical Biology

A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily

(2015) Pau Biak Sang et al.   NUCLEIC ACIDS RESEARCH

Antimycobacterial activity of peptide conjugate of pyridopyrimidine derivative against Mycobacterium tuberculosis in a series of in vitro and in vivo models

(2015) Kata Horváti et al.   TUBERCULOSIS

Base excision repair: A critical player in many games

(2014) Susan S. Wallace   DNA REPAIR

Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target

(2014) Thidarat Suksangpleng et al.   MALARIA JOURNAL

Antibiotics induce redox-related physiological alterations as part of their lethality

(2014) D. J. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification through structure-based methods of a bacterial NAD+-dependent DNA ligase inhibitor that avoids known resistance mutations

(2013) Kerry Murphy-Benenato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biochemical Properties of MutT2 Proteins from Mycobacterium tuberculosis and M. smegmatis and Their Contrasting Antimutator Roles in Escherichia coli

(2013) P. B. Sang et al.   JOURNAL OF BACTERIOLOGY

Hypersensitivity of hypoxia grown Mycobacterium smegmatis to DNA damaging agents: Implications of the DNA repair deficiencies in attenuation of mycobacteria

(2013) Kervin Rex et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

(2013) Aaron C. Jacobs et al.   PLoS One

Base Excision Repair

(2013) H. E. Krokan et al.   Cold Spring Harbor Perspectives in Biology

A network of enzymes involved in repair of oxidative DNA damage in Neisseria meningitidis

(2012) Krzysztofa Nagorska et al.   MOLECULAR MICROBIOLOGY

Totally drug-resistant tuberculosis in India: Who let the djinn out?

(2012) Zarir F. Udwadia   RESPIROLOGY

Totally Drug-Resistant Tuberculosis in India

(2011) Z. F. Udwadia et al.   CLINICAL INFECTIOUS DISEASES

Design, Synthesis, and Study of a Mycobactin−Artemisinin Conjugate That Has Selective and Potent Activity against Tuberculosis and Malaria

(2011) Marvin J. Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uracil excision repair in Mycobacterium tuberculosis cell-free extracts

(2011) Pradeep Kumar et al.   TUBERCULOSIS

Base excision and nucleotide excision repair pathways in mycobacteria

(2011) Krishna Kurthkoti et al.   TUBERCULOSIS

Unexpected Role for Helicobacter pylori DNA Polymerase I As a Source of Genetic Variability

(2011) María-Victoria García-Ortíz et al.   PLoS Genetics

Recombination and DNA Repair inHelicobacter pylori

(2010) Marion S. Dorer et al.   Annual Review of Microbiology

Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial EfficacyIn Vivo

(2010) Scott D. Mills et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Relevance of DNA Alkylation Damage Repair Systems in Salmonella enterica Virulence

(2010) G. Alvarez et al.   JOURNAL OF BACTERIOLOGY

Detrimental Effects of Hypoxia-Specific Expression of Uracil DNA Glycosylase (Ung) in Mycobacterium smegmatis

(2010) K. Kurthkoti et al.   JOURNAL OF BACTERIOLOGY

Genetic Requirements for the Survival of Tubercle Bacilli in Primates

(2010) Noton K. Dutta et al.   JOURNAL OF INFECTIOUS DISEASES

Novel Small-Molecule Inhibitor of Apurinic/Apyrimidinic Endonuclease 1 Blocks Proliferation and Reduces Viability of Glioblastoma Cells

(2010) A. Bapat et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair

(2009) Katrina L Tibballs et al.   BMC MICROBIOLOGY

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation

(2009) April M Reed et al.   Future Oncology

Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis

(2009) V. S. Malshetty et al.   MICROBIOLOGY-SGM

Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase β in long patch base excision repair

(2009) Maria Sukhanova et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The Base Excision Repair System of Salmonella enterica serovar Typhimurium Counteracts DNA Damage by Host Nitric Oxide

(2009) Anthony R. Richardson et al.   PLoS Pathogens

Active site of mycobacterial dUTPase: Structural characteristics and a built-in sensor

(2008) Balázs Varga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel DNA glycosylases from Mycobacterium tuberculosis

(2008) V. S. Sidorenko et al.   BIOCHEMISTRY-MOSCOW

Pseudomonas aeruginosa deficient in 8-oxodeoxyguanine repair system shows a high frequency of resistance to ciprofloxacin

(2008) Natalia R. Morero et al.   FEMS MICROBIOLOGY LETTERS