Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota

Critical Analysis of Drug Product Recalls due to Nitrosamine Impurities

(2021) Sonali S. Bharate   JOURNAL OF MEDICINAL CHEMISTRY

Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut

(2021) Steven G. Sutcliffe et al.   Viruses-Basel

Magnetic Living Hydrogels for Intestinal Localization, Retention, and Diagnosis

(2021) Xinyue Liu et al.   ADVANCED FUNCTIONAL MATERIALS

In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship

(2021) Francesco Crudo et al.   ARCHIVES OF TOXICOLOGY

Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23

(2021) Zhengxiang He et al.   Cell Metabolism

Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria, E. coli and E. faecalis

(2021) Aparna Shil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Towards a mechanistic understanding of reciprocal drug–microbiome interactions

(2021) Michael Zimmermann et al.   Molecular Systems Biology

Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation

(2021) Md Masud Parvez et al.   DRUG METABOLISM AND DISPOSITION

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

(2021) Shuo Han et al.   NATURE

Bioaccumulation of therapeutic drugs by human gut bacteria

(2021) Martina Klünemann et al.   NATURE

“Waste Not, Want Not” — Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical Monitoring

(2021) Timothy B. Erickson et al.   Journal of Medical Toxicology

Unravelling the collateral damage of antibiotics on gut bacteria

(2021) Lisa Maier et al.   NATURE

Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

(2020) Arnau Vich Vila et al.   Nature Communications

Insights into the Role of Human Gut Microbiota in Clostridioides difficile Infection

(2020) Melina Kachrimanidou et al.   Microorganisms

Low-concentration of dichloroacetonitrile (DCAN) in drinking water perturbs the health-associated gut microbiome and metabolic profile in rats

(2020) Bin Xue et al.   CHEMOSPHERE

Interaction between drugs and the gut microbiome

(2020) Rinse K Weersma et al.   GUT

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

(2020) Sara Vieira-Silva et al.   NATURE

The Impact of Environmental Chemicals on the Gut Microbiome

(2020) Karen Chiu et al.   TOXICOLOGICAL SCIENCES

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

(2020) Elizabeth M. Grimsey et al.   mBio

Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics

(2020) Nehal Adel Abdelsalam et al.   Frontiers in Pharmacology

Metabolome–Microbiome Crosstalk and Human Disease

(2020) Kathleen A. Lee-Sarwar et al.   Metabolites

Personalized Mapping of Drug Metabolism by the Human Gut Microbiome

(2020) Bahar Javdan et al.   CELL

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses

(2020) David A. Hughes et al.   Nature Microbiology

Gut microbial metabolites as multi-kingdom intermediates

(2020) Kimberly A. Krautkramer et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

(2020) Emilie Viennois et al.   Cell Reports

Prevalent Human Gut Bacteria Hydrolyse and Metabolise Important Food-Derived Mycotoxins and Masked Mycotoxins

(2020) Noshin Daud et al.   Toxins

The gut microbiome and antipsychotic treatment response

(2020) Mary V. Seeman   BEHAVIOURAL BRAIN RESEARCH

Drug–Exposome Interactions: The Next Frontier in Precision Medicine

(2020) Manuel Pristner et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Pre‐treatment Gut Microbiome is Associated with Lack of Response to Methotrexate in New Onset Rheumatoid Arthritis

(2020) Alejandro Artacho et al.   Arthritis & Rheumatology

Separating host and microbiome contributions to drug pharmacokinetics and toxicity

(2019) Michael Zimmermann et al.   SCIENCE

Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites

(2019) Xuanji Li et al.   ENVIRONMENT INTERNATIONAL

Consumption of drinking water N-Nitrosamines mixture alters gut microbiome and increases the obesity risk in young male rats

(2019) Jianqiang Zhu et al.   ENVIRONMENTAL POLLUTION

Gut microbiota: An underestimated and unintended recipient for pesticide-induced toxicity

(2019) Xianling Yuan et al.   CHEMOSPHERE

Mapping human microbiome drug metabolism by gut bacteria and their genes

(2019) Michael Zimmermann et al.   NATURE

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

(2019) Vayu Maini Rekdal et al.   SCIENCE

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

(2019) Rosina Pryor et al.   CELL

Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited ‘FAO estimate’ of 25%

(2019) Mari Eskola et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Translating the gut microbiome: ready for the clinic?

(2019) Susan V. Lynch et al.   Nature Reviews Gastroenterology & Hepatology

Diet–microbiota interactions and personalized nutrition

(2019) Aleksandra A. Kolodziejczyk et al.   NATURE REVIEWS MICROBIOLOGY

The gut microbiome in neurological disorders

(2019) John F Cryan et al.   LANCET NEUROLOGY

Current explorations of nutrition and the gut microbiome: a comprehensive evaluation of the review literature

(2019) Leigh A Frame et al.   NUTRITION REVIEWS

Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice

(2018) Cécile Vignal et al.   ARCHIVES OF TOXICOLOGY

Critical review of major sources of human exposure to N -nitrosamines

(2018) Adam J. Gushgari et al.   CHEMOSPHERE

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

(2018) Alexander Rodriguez-Palacios et al.   INFLAMMATORY BOWEL DISEASES

Trigonelline inhibits intestinal microbial metabolism of choline and its associated cardiovascular risk

(2018) Siraj Anwar et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The fecal metabolome as a functional readout of the gut microbiome

(2018) Jonas Zierer et al.   NATURE GENETICS

Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice

(2018) Yassine Aitbali et al.   NEUROTOXICOLOGY AND TERATOLOGY

An ingestible bacterial-electronic system to monitor gastrointestinal health

(2018) Mark Mimee et al.   SCIENCE

OUP accepted manuscript

(2018)   Advances in Nutrition

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

(2018) Jotham Suez et al.   CELL

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

Dietary trehalose enhances virulence of epidemic Clostridium difficile

(2018) J. Collins et al.   NATURE

Species-specific activity of antibacterial drug combinations

(2018) Ana Rita Brochado et al.   NATURE

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

Long-term impact of oral vancomycin, ciprofloxacin and metronidazole on the gut microbiota in healthy humans

(2018) Bastiaan W Haak et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Translating microbiome futures

(2018) Gaspar Taroncher-Oldenburg et al.   NATURE BIOTECHNOLOGY

The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

(2018) Michael Coryell et al.   Nature Communications

Recovery of gut microbiota of healthy adults following antibiotic exposure

(2018) Albert Palleja et al.   Nature Microbiology

Gut microbiome structure and metabolic activity in inflammatory bowel disease

(2018) Eric A. Franzosa et al.   Nature Microbiology

Saccharin induced liver inflammation in mice by altering the gut microbiota and its metabolic functions

(2017) Xiaoming Bian et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation

(2017) Benoit Chassaing et al.   GUT

Prebiotic Potential and Chemical Composition of Seven Culinary Spice Extracts

(2017) Qing-Yi Lu et al.   JOURNAL OF FOOD SCIENCE

The modulatory effect of polyphenols from green tea, oolong tea and black tea on human intestinal microbiota in vitro

(2017) Hanyang Sun et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Food additives, contaminants and other minor components: effects on human gut microbiota—a review

(2017) Paula Roca-Saavedra et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Masked trichothecene and zearalenone mycotoxins withstand digestion and absorption in the upper GI tract but are efficiently hydrolyzed by human gut microbiota in vitro

(2017) Silvia W. Gratz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Ménage à trois in the human gut: interactions between host, bacteria and phages

(2017) Mohammadali Khan Mirzaei et al.   NATURE REVIEWS MICROBIOLOGY

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

(2017) Leore T. Geller et al.   SCIENCE

Chemical transformation of xenobiotics by the human gut microbiota

(2017) Nitzan Koppel et al.   SCIENCE

Occurrence, Toxicity, and Analysis of Major Mycotoxins in Food

(2017) Ahmad Alshannaq et al.   International Journal of Environmental Research and Public Health

Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice

(2017) Qixiao Zhai et al.   Science Bulletin

Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

(2016) Emilie Viennois et al.   CANCER RESEARCH

The complex interplay of diet, xenobiotics, and microbial metabolism in the gut: Implications for clinical outcomes

(2016) M Taguer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection

(2016) Joseph P Zackular et al.   NATURE MEDICINE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats

(2016) Julie Reygner et al.   PLoS One

Determining the Long-term Effect of Antibiotic Administration on the Human Normal Intestinal Microbiota Using Culture and Pyrosequencing Methods

(2015) Mamun-Ur Rashid et al.   CLINICAL INFECTIOUS DISEASES

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Antibiotics and the gut microbiota

(2014) Sheetal R. Modi et al.   JOURNAL OF CLINICAL INVESTIGATION

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Combination of Metagenomics and Culture-Based Methods to Study the Interaction Between Ochratoxin A and Gut Microbiota

(2014) Mingzhang Guo et al.   TOXICOLOGICAL SCIENCES

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

(2013) Filipe Cabreiro et al.   CELL

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Control of pathogens and pathobionts by the gut microbiota

(2013) Nobuhiko Kamada et al.   NATURE IMMUNOLOGY

Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta

(2013) H. J. Haiser et al.   SCIENCE

Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria

(2012) Hongmiao Pan et al.   ANAEROBE

The microbiome as a human organ

(2012) F. Baquero et al.   CLINICAL MICROBIOLOGY AND INFECTION

Isolation, identification and characterization of human intestinal bacteria with the ability to utilize chloramphenicol as the sole source of carbon and energy

(2012) Zhao Xin et al.   FEMS MICROBIOLOGY ECOLOGY

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Efficiency of the intestinal bacteria in the degradation of the toxic pesticide, chlorpyrifos

(2012) M. K. Harishankar et al.   3 Biotech

Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women

(2011) William H. Goodson et al.   CARCINOGENESIS

Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity

(2010) Maya A. Farha et al.   CHEMISTRY & BIOLOGY

Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract

(2009) Haiyan Xu et al.   ANAEROBE