Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells

New Insights Into Blood-Brain Barrier Maintenance: The Homeostatic Role of β-Amyloid Precursor Protein in Cerebral Vasculature

(2020) Emma Ristori et al.   Frontiers in Physiology

N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165-dependent neovascularization

(2019) Federico Corti et al.   Nature Communications

Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells

(2018) Ruohan Sun et al.   Aging-US

The Vascular Hypothesis of Alzheimer’s Disease: A Key to Preclinical Prediction of Dementia Using Neuroimaging

(2018) Jack de la Torre   JOURNAL OF ALZHEIMERS DISEASE

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties

(2018) G. Nannelli et al.   Oxidative Medicine and Cellular Longevity

β1-integrin–matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability

(2017) Yoshikane Izawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Endothelium-specific amyloid precursor protein deficiency causes endothelial dysfunction in cerebral arteries

(2017) Livius V d’Uscio et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system

(2017) Lucas J. Sosa et al.   JOURNAL OF NEUROCHEMISTRY

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

(2016) Julien Chapuis et al.   ACTA NEUROPATHOLOGICA

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

The kindlin family: functions, signaling properties and implications for human disease

(2016) Emanuel Rognoni et al.   JOURNAL OF CELL SCIENCE

Efficacy of AdipoDren® in Reducing Interleukin-1-Induced Lymphatic Endothelial Hyperpermeability

(2016) Valerio Ciccone et al.   JOURNAL OF VASCULAR RESEARCH

Impaired Integrin β3 Delays Endothelial Cell Regeneration and Contributes to Arteriovenous Graft Failure in MiceSignificance

(2015) Ming Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Review of Cell Adhesion Studies for Biomedical and Biological Applications

(2015) Amelia Khalili et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

(2015) Olga Tornavaca et al.   JOURNAL OF CELL BIOLOGY

Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease

(2014) Edgar Dawkins et al.   JOURNAL OF NEUROCHEMISTRY

Antagonism of Bradykinin B2 Receptor Prevents Inflammatory Responses in Human Endothelial Cells by Quenching the NF-kB Pathway Activation

(2014) Erika Terzuoli et al.   PLoS One

Redundancy and divergence in the amyloid precursor protein family

(2013) S. Ali M. Shariati et al.   FEBS LETTERS

Soluble amyloid-  precursor protein binds its cell surface receptor in a cooperative fashion with glypican and syndecan proteoglycans

(2013) C. Reinhard et al.   JOURNAL OF CELL SCIENCE

Endothelial adherens junctions at a glance

(2013) E. Dejana et al.   JOURNAL OF CELL SCIENCE

The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110

(2013) Frances Corrigan et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid Precursor Protein Is an Autonomous Growth Cone Adhesion Molecule Engaged in Contact Guidance

(2013) Lucas J. Sosa et al.   PLoS One

Amyloid-β and APP Deficiencies Cause Severe Cerebrovascular Defects: Important Work for an Old Villain

(2013) Salvadore Luna et al.   PLoS One

APP Knockout Mice Experience Acute Mortality as the Result of Ischemia

(2012) Maya A. Koike et al.   PLoS One

The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains

(2011) Frances Corrigan et al.   BRAIN RESEARCH

Selective Interaction of Amyloid Precursor Protein with Different Isoforms of Neural Cell Adhesion Molecule

(2011) Ke-ping Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis

(2009) Payaningal R. Somanath et al.   ANGIOGENESIS

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth

(2009) H.-S. Hoe et al.   JOURNAL OF NEUROSCIENCE

Expression of amyloid precursor protein after rat traumatic brain injury

(2009) Tatsuki Itoh et al.   NEUROLOGICAL RESEARCH

The Integrin Antagonist Cilengitide Activates αVβ3, Disrupts VE-Cadherin Localization at Cell Junctions and Enhances Permeability in Endothelial Cells

(2009) Gian Carlo Alghisi et al.   PLoS One

Sodium-deoxycholate-assisted tryptic digestion and identification of proteolytically resistant proteins

(2008) Yong Lin et al.   ANALYTICAL BIOCHEMISTRY

Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees

(2008) Elisabetta Dejana et al.   CELL AND TISSUE RESEARCH

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning

(2007) Yann Senechal et al.   BEHAVIOURAL BRAIN RESEARCH

The effect of stress on the expression of the amyloid precursor protein in rat brain

(2007) Rachel Sayer et al.   NEUROSCIENCE LETTERS