Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-12-14
DOI
10.1038/s41380-021-01394-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
- (2021) Hossam Montaser et al. DIABETES
- The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
- (2021) Ave Eesmaa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP+ in dissociated cultures from rat mesencephalon
- (2021) Juliann D. Jaumotte et al. PLoS One
- Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo
- (2021) Katrina Albert et al. MOLECULAR THERAPY
- Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
- (2020) Anni Herranen et al. Cell Death & Disease
- Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart
- (2020) Adrian Arrieta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cerebral Dopamine Neurotrophic Factor Is Essential for Enteric Neuronal Development, Maintenance and Regulation of Gastrointestinal Transit
- (2020) Alcmène Chalazonitis et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Mechanisms, regulation and functions of the unfolded protein response
- (2020) Claudio Hetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cerebral Dopamine Neurotrophic Factor Regulates Multiple Neuronal Subtypes and Behavior
- (2020) Yu-Chia Chen et al. JOURNAL OF NEUROSCIENCE
- Trophic activities of endoplasmic reticulum proteins CDNF and MANF
- (2020) Maria Jӓntti et al. CELL AND TISSUE RESEARCH
- GDNF / RET Signaling Pathway Activation Eliminates Lewy Body Pathology in Midbrain Dopamine Neurons
- (2020) Piotr Chmielarz et al. MOVEMENT DISORDERS
- Can Growth Factors Cure Parkinson’s Disease?
- (2020) Yulia A. Sidorova et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The Future of GDNF in Parkinson's Disease
- (2020) Fredric P. Manfredsson et al. Frontiers in Aging Neuroscience
- New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K‐AKT Pathway Via a Putative KDEL‐Receptor Binding
- (2020) Leonardo Maciel et al. Journal of the American Heart Association
- Neuroplastin Modulates Anti-inflammatory Effects of MANF
- (2020) Takuya Yagi et al. iScience
- The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
- (2019) G. Elif Karagöz et al. Cold Spring Harbor Perspectives in Biology
- Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy
- (2019) Emilia Galli et al. CELL TRANSPLANTATION
- Levels of glial cell line‐derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in parkinson's disease
- (2019) Sophie Virachit et al. BRAIN PATHOLOGY
- CDNF Protein Therapy in Parkinson’s Disease
- (2019) Henri J. Huttunen et al. CELL TRANSPLANTATION
- Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins – mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor
- (2019) Katrina Albert et al. CROATIAN MEDICAL JOURNAL
- MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa
- (2019) Jessica H. Hartman et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Parkinson disease and growth factors — is GDNF good enough?
- (2019) Agnete Kirkeby et al. Nature Reviews Neurology
- Linking the Endoplasmic Reticulum to Parkinson’s Disease and Alpha-Synucleinopathy
- (2019) Emanuela Colla Frontiers in Neuroscience
- Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra
- (2019) Katrina Albert et al. Frontiers in Neuroscience
- Increased Serum Levels of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Subjects With Parkinson’s Disease
- (2019) Emilia Galli et al. Frontiers in Neuroscience
- Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function
- (2019) Tatiana Danilova et al. Frontiers in Endocrinology
- Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
- (2019) Maria Lindahl et al. NEUROBIOLOGY OF DISEASE
- MANF protects human pancreatic beta cells against stress-induced cell death
- (2018) Elina Hakonen et al. DIABETOLOGIA
- XBP1 activation enhances MANF expression via binding to endoplasmic reticulum stress response elements within MANF promoter region in hepatitis B
- (2018) Dong Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway
- (2018) Geng-Lin Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
- (2018) Peng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling
- (2018) Jenny Sandmark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson’s Disease
- (2018) Antti Huotarinen et al. NEUROSCIENCE
- The Parkinson Pandemic—A Call to Action
- (2018) E. Ray Dorsey et al. JAMA Neurology
- CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress-induced cell death
- (2018) Duxan Arancibia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response
- (2018) Cory Richman et al. Frontiers in Neuroscience
- Cerebral dopamine neurotrophic factor protects microglia by combining with AKT and by regulating FoxO1/mTOR signaling during neuroinflammation
- (2018) Yayun Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic β-Cell Mass in Mice
- (2018) Tatiana Danilova et al. DIABETES
- Early Events in the Endoplasmic Reticulum Unfolded Protein Response
- (2018) Steffen Preissler et al. Cold Spring Harbor Perspectives in Biology
- Trophic Factors in Inflammation and Regeneration: The Role of MANF and CDNF
- (2018) Pedro Sousa-Victor et al. Frontiers in Physiology
- Long-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats
- (2017) Fei Hao et al. EXPERIMENTAL NEUROLOGY
- Cerebral dopamine neurotrophic factor protects H9c2 cardiomyocytes from apoptosis
- (2017) H. Liu et al. HERZ
- Recombinant AAV8-mediated intrastriatal gene delivery of CDNF protects rats against methamphetamine neurotoxicity
- (2017) Lizheng Wang et al. International Journal of Medical Sciences
- Epidemiology of Parkinson’s disease
- (2017) Ole-Bjørn Tysnes et al. JOURNAL OF NEURAL TRANSMISSION
- ER stress and the unfolded protein response in neurodegeneration
- (2017) Claudio Hetz et al. Nature Reviews Neurology
- Non-motor features of Parkinson disease
- (2017) Anthony H. V. Schapira et al. NATURE REVIEWS NEUROSCIENCE
- Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential
- (2017) Maria Lindahl et al. NEUROBIOLOGY OF DISEASE
- Therapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression
- (2017) Lizheng Wang et al. PLoS One
- Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology, and therapeutic roles
- (2017) Yeawon Kim et al. Translational Research
- An unfolded protein-induced conformational switch activates mammalian IRE1
- (2017) G Elif Karagöz et al. eLife
- Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells
- (2017) Miriam Cnop et al. Molecular Metabolism
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease
- (2016) Pia Runeberg-Roos et al. NEUROBIOLOGY OF DISEASE
- Cerebral dopamine neurotrophic factor alleviates Aβ 25-35 -induced endoplasmic reticulum stress and early synaptotoxicity in rat hippocampal cells
- (2016) Wei Zhou et al. NEUROSCIENCE LETTERS
- A Comparative Analysis of the Molecular Features of MANF and CDNF
- (2016) Junpei Norisada et al. PLoS One
- Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson’s Disease
- (2016) Enrique Garea-Rodríguez et al. PLoS One
- Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes
- (2016) Emilia Galli et al. Scientific Reports
- Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
- (2015) Susanna Kemppainen et al. BEHAVIOURAL BRAIN RESEARCH
- High diagnostic yield of clinical exome sequencing in Middle Eastern patients with Mendelian disorders
- (2015) Tarunashree Yavarna et al. HUMAN GENETICS
- The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers
- (2015) Cristiane Latge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhanced Efficacy of the CDNF/MANF Family by Combined Intranigral Overexpression in the 6-OHDA Rat Model of Parkinson's Disease
- (2015) Óscar Cordero-Llana et al. MOLECULAR THERAPY
- Trophic factors for Parkinson's disease: To live or let die
- (2015) C. Warren Olanow et al. MOVEMENT DISORDERS
- Unfolded protein response is activated in Lewy body dementias
- (2015) Jean-Ha Baek et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity
- (2015) K Mätlik et al. Cell Death & Disease
- Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
- (2014) Rasajna Nadella et al. Journal of Neuroinflammation
- Effects of engineered conserved dopamine neurotrophic factor-expressing bone marrow stromal cells on dopaminergic neurons following 6-OHDA administrations
- (2014) JIAMING MEI et al. Molecular Medicine Reports
- Transplantation of Cerebral Dopamine Neurotrophic Factor Transducted BMSCs in Contusion Spinal Cord Injury of Rats: Promotion of Nerve Regeneration by Alleviating Neuroinflammation
- (2014) Hua Zhao et al. MOLECULAR NEUROBIOLOGY
- Comparing neuroprotective effects of CDNF-expressing bone marrow derived mesenchymal stem cells via differing routes of administration utilizing an in vivo model of Parkinson’s disease
- (2014) Mei Jiaming et al. NEUROLOGICAL SCIENCES
- Effects of CDNF on 6-OHDA-induced apoptosis in PC12 cells via modulation of Bcl-2/Bax and caspase-3 activation
- (2014) Jia-ming Mei et al. NEUROLOGICAL SCIENCES
- Construction of bicistronic lentiviral vectors for tracking the expression of CDNF in transduced cells
- (2014) Anllely Fernández et al. PLASMID
- MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells
- (2014) Maria Lindahl et al. Cell Reports
- Overexpression of conserved dopamine neurotrophic factor (CDNF) in astrocytes alleviates endoplasmic reticulum stress-induced cell damage and inflammatory cytokine secretion
- (2013) Lei Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model
- (2013) Xinmiao Ren et al. EXPERIMENTAL NEUROLOGY
- Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases
- (2013) Claire L. Hartley et al. HUMAN MOLECULAR GENETICS
- Mechanisms of Anti-inflammatory Property of Conserved Dopamine Neurotrophic Factor: Inhibition of JNK Signaling in Lipopolysaccharide-Induced Microglia
- (2013) Hua Zhao et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Trophic Factor Gene Therapy for Parkinson's Disease
- (2013) Jeffrey H. Kordower et al. MOVEMENT DISORDERS
- GDNF, NGF and BDNF as therapeutic options for neurodegeneration
- (2013) Shelley J. Allen et al. PHARMACOLOGY & THERAPEUTICS
- Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
- (2013) Riitta Lindström et al. PLoS One
- An ERcentric view of Parkinson's disease
- (2013) Gabriela Mercado et al. TRENDS IN MOLECULAR MEDICINE
- Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease
- (2013) Susanne Bäck et al. Brain and Behavior
- Glial cell line-derived neurotrophic factor: Characterization of mammalian posttranslational modifications
- (2012) Elisa Piccinini et al. ANNALS OF MEDICINE
- Gene expression analysis of Drosophila Manf mutants reveals perturbations in membrane traffic and major metabolic changes
- (2012) Mari Palgi et al. BMC GENOMICS
- MANF regulates dopaminergic neuron development in larval zebrafish
- (2012) Y.-C. Chen et al. DEVELOPMENTAL BIOLOGY
- Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors
- (2012) Mark J. Henderson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion
- (2012) Christopher C. Glembotski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An efficient one-step radiosynthesis of [18F]FE-PE2I, a PET radioligand for imaging of dopamine transporters
- (2012) Vladimir Stepanov et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders
- (2012) Koichi Wakabayashi et al. MOLECULAR NEUROBIOLOGY
- GDNF fails to exert neuroprotection in a rat -synuclein model of Parkinson's disease
- (2011) M. Decressac et al. BRAIN
- CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery after MPTP Treatment in Mice
- (2011) Mikko Airavaara et al. CELL TRANSPLANTATION
- Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin
- (2011) Maxim M. Bespalov et al. JOURNAL OF CELL BIOLOGY
- Intracellular trafficking and secretion of cerebral dopamine neurotrophic factor in neurosecretory cells
- (2011) Zong-Peng Sun et al. JOURNAL OF NEUROCHEMISTRY
- Intracellular trafficking and secretion of mouse mesencephalic astrocyte-derived neurotrophic factor
- (2011) Kentaro Oh-hashi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Analysis of mutations and the association between polymorphisms in the cerebral dopamine neurotrophic factor (CDNF) gene and Parkinson disease
- (2011) Jung-Mi Choi et al. NEUROSCIENCE LETTERS
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response
- (2011) B. M. Gardner et al. SCIENCE
- Clinical progression in Parkinson disease and the neurobiology of axons
- (2010) Hsiao-Chun Cheng et al. ANNALS OF NEUROLOGY
- Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
- (2010) Merja H. Voutilainen et al. EXPERIMENTAL NEUROLOGY
- Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
- (2010) Maarit Hellman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of the Intracellular Localization, Processing, and Secretion of Two Glial Cell Line-Derived Neurotrophic Factor Splice Isoforms
- (2010) L. Lonka-Nevalaita et al. JOURNAL OF NEUROSCIENCE
- Induction Profile of MANF/ARMET by Cerebral Ischemia and its Implication for Neuron Protection
- (2009) Yong-Qiang Yu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease
- (2009) M. H. Voutilainen et al. JOURNAL OF NEUROSCIENCE
- Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
- (2009) M. Palgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
- (2009) Vimal Parkash et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart
- (2008) Archana Tadimalla et al. CIRCULATION RESEARCH
- The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
- (2008) Décio L. Eizirik et al. ENDOCRINE REVIEWS
- Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
- (2008) A APOSTOLOU et al. EXPERIMENTAL CELL RESEARCH
- The Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex
- (2008) Vimal Parkash et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain
- (2008) Päivi Lindholm et al. MOLECULAR AND CELLULAR NEUROSCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started