C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response

Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection

(2018) Meirong Bai et al.   Nature Communications

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating GRP78 in SH-SY5Y cells

(2016) Jingwei Huang et al.   CELL BIOLOGY INTERNATIONAL

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster

(2016) Riitta Lindström et al.   PLoS One

Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease

(2015) Merja H. Voutilainen et al.   FEBS LETTERS

Analysis of the conserved neurotrophic factor MANF in the Drosophila adult brain

(2015) Vassilis Stratoulias et al.   GENE EXPRESSION PATTERNS

The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers

(2015) Cristiane Latge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer

(2014) Tamar Hashimshony et al.   NATURE

Conservation of mRNA and Protein Expression during Development of C. elegans

(2014) Dominic Grün et al.   Cell Reports

Developmental Milestones Punctuate Gene Expression in the Caenorhabditis Embryo

(2012) Michal Levin et al.   DEVELOPMENTAL CELL

Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors

(2012) Mark J. Henderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER stress response plays an important role in aggregation of α-synuclein

(2011) Peizhou Jiang et al.   Molecular Neurodegeneration

Solution structure and dynamics of mouse ARMET

(2010) Jun Hoseki et al.   FEBS LETTERS

Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons

(2010) Maarit Hellman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction Profile of MANF/ARMET by Cerebral Ischemia and its Implication for Neuron Protection

(2009) Yong-Qiang Yu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats

(2009) Mikko Airavaara et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease

(2009) M. H. Voutilainen et al.   JOURNAL OF NEUROSCIENCE

Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons

(2009) M. Palgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional

(2009) Vimal Parkash et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Age-related behaviors have distinct transcriptional profiles inCaenorhabditis elegans

(2008) Tamara R. Golden et al.   AGING CELL

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart

(2008) Archana Tadimalla et al.   CIRCULATION RESEARCH

Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death

(2008) A APOSTOLOU et al.   EXPERIMENTAL CELL RESEARCH

MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain

(2008) Päivi Lindholm et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

(2008) S. Hamamichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging

(2008) Tjakko J. van Ham et al.   PLoS Genetics