- Home
- Publications
- Publication Search
- Publication Details
Title
Trophic activities of endoplasmic reticulum proteins CDNF and MANF
Authors
Keywords
-
Journal
CELL AND TISSUE RESEARCH
Volume 382, Issue 1, Pages 83-100
Publisher
Springer Science and Business Media LLC
Online
2020-08-26
DOI
10.1007/s00441-020-03263-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Decreased Circulating MANF in Women with PCOS is Elevated by Metformin Therapy and is Inversely Correlated with Insulin Resistance and Hyperandrogenism
- (2020) Jie Wei et al. HORMONE AND METABOLIC RESEARCH
- Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
- (2020) Anni Herranen et al. Cell Death & Disease
- MANF Promotes Diabetic Corneal Epithelial Wound Healing and Nerve Regeneration by Attenuating Hyperglycemia-Induced Endoplasmic Reticulum Stress
- (2020) Xiaochuan Wang et al. DIABETES
- Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart
- (2020) Adrian Arrieta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease
- (2020) Nihad Tousson-Abouelazm et al. LABORATORY INVESTIGATION
- A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome
- (2020) Jana Mahadevan et al. LABORATORY INVESTIGATION
- Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism
- (2020) Miao He et al. WORLD JOURNAL OF GASTROENTEROLOGY
- MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice
- (2020) Joana Neves et al. EXPERIMENTAL GERONTOLOGY
- Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF
- (2020) Jaakko Teppo et al. EXPERIMENTAL NEUROLOGY
- Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover
- (2020) Jili Fu et al. LIFE SCIENCES
- MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP
- (2019) Yahui Yan et al. Nature Communications
- Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress
- (2019) Shengchun Xu et al. Journal of Neuroinflammation
- Levels of glial cell line‐derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in parkinson's disease
- (2019) Sophie Virachit et al. BRAIN PATHOLOGY
- Secondary Pathology of the Thalamus after Focal Cortical Stroke in Rats is not Associated with Thermal or Mechanical Hypersensitivity and is Not Alleviated by Intra-Thalamic Post-Stroke Delivery of Recombinant CDNF or MANF
- (2019) Jenni E. Anttila et al. CELL TRANSPLANTATION
- CDNF Protein Therapy in Parkinson’s Disease
- (2019) Henri J. Huttunen et al. CELL TRANSPLANTATION
- Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins – mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor
- (2019) Katrina Albert et al. CROATIAN MEDICAL JOURNAL
- MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa
- (2019) Jessica H. Hartman et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome
- (2019) Sun-Ji Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MANF inhibits liver cancer via SUMO ylation‐related suppression of NF ‐κB/Snail signaling pathway and epithelial‐mesenchymal transition
- (2019) Jun Liu et al. HEPATOLOGY
- MANF regulates splenic macrophage differentiation in mice
- (2019) Chao Hou et al. IMMUNOLOGY LETTERS
- Increased Serum Levels of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Subjects With Parkinson’s Disease
- (2019) Emilia Galli et al. Frontiers in Neuroscience
- Circulating Mesencephalic Astrocyte-derived Neurotrophic Factor Negatively Correlates with Atrial Apoptosis in Human Chronic Atrial Fibrillation
- (2019) Changhui Wang et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice
- (2019) Emilia Galli et al. Scientific Reports
- Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function
- (2019) Tatiana Danilova et al. Frontiers in Endocrinology
- Decreased Expression of Cerebral Dopamine Neurotrophic Factor in Platelets of Stroke Patients
- (2019) Hetshree Joshi et al. Journal of Stroke & Cerebrovascular Diseases
- Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
- (2019) Maria Lindahl et al. NEUROBIOLOGY OF DISEASE
- Effects of mesencephalic astrocyte-derived neurotrophic factor on cerebral angiogenesis in a rat model of cerebral ischemia
- (2019) Baobing Gao et al. NEUROSCIENCE LETTERS
- MANF attenuates neuronal apoptosis and promotes behavioral recovery via Akt/MDM-2/p53 pathway after traumatic spinal cord injury in rats
- (2018) Liansheng Gao et al. BIOFACTORS
- MANF protects human pancreatic beta cells against stress-induced cell death
- (2018) Elina Hakonen et al. DIABETOLOGIA
- MANF protects dopamine neurons and locomotion defects from a human α-synuclein induced Parkinson's disease model in C. elegans by regulating ER stress and autophagy pathways
- (2018) Zhuoyu Zhang et al. EXPERIMENTAL NEUROLOGY
- At the crossway of ER-stress and proinflammatory responses
- (2018) Marisa Reverendo et al. FEBS Journal
- XBP1 activation enhances MANF expression via binding to endoplasmic reticulum stress response elements within MANF promoter region in hepatitis B
- (2018) Dong Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway
- (2018) Geng-Lin Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
- (2018) Timothy J. Bergmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Piperine ameliorates SCA17 neuropathology by reducing ER stress
- (2018) Jifeng Guo et al. Molecular Neurodegeneration
- MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
- (2018) Kuan-Yin Tseng et al. MOLECULAR THERAPY
- Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson’s Disease
- (2018) Antti Huotarinen et al. NEUROSCIENCE
- Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection
- (2018) Meirong Bai et al. Nature Communications
- Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Protects Against Neuronal Apoptosis via Activation of Akt/MDM2/p53 Signaling Pathway in a Rat Model of Intracerebral Hemorrhage
- (2018) Weilin Xu et al. Frontiers in Molecular Neuroscience
- Poststroke delivery of MANF promotes functional recovery in rats
- (2018) Kert Mätlik et al. Science Advances
- CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress-induced cell death
- (2018) Duxan Arancibia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mesencephalic astrocyte-derived neurotrophic factor affords neuroprotection to early brain injury induced by subarachnoid hemorrhage via activating Akt-dependent prosurvival pathway and defending blood–brain barrier integrity
- (2018) Tao Li et al. FASEB JOURNAL
- C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response
- (2018) Cory Richman et al. Frontiers in Neuroscience
- Cerebral dopamine neurotrophic factor protects microglia by combining with AKT and by regulating FoxO1/mTOR signaling during neuroinflammation
- (2018) Yayun Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis
- (2018) P. A. Bell et al. CELL STRESS & CHAPERONES
- KDEL Receptors Are Differentially Regulated to Maintain the ER Proteome under Calcium Deficiency
- (2018) Kathleen A. Trychta et al. Cell Reports
- Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage via ROS-AMPK/mTOR mediated autophagic inhibition
- (2017) Jingxing Zhang et al. EXPERIMENTAL GERONTOLOGY
- Cerebral dopamine neurotrophic factor protects H9c2 cardiomyocytes from apoptosis
- (2017) H. Liu et al. HERZ
- Characterization of aromatic residue–controlled protein retention in the endoplasmic reticulum ofSaccharomyces cerevisiae
- (2017) Meng Mei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)
- (2017) Daniel A. Cunha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression
- (2017) Lizheng Wang et al. PLoS One
- MANF regulates hypothalamic control of food intake and body weight
- (2017) Su Yang et al. Nature Communications
- Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells
- (2017) Hui Sun et al. Translational Neurodegeneration
- Mesencephalic astrocyte-derived neurotrophic factor attenuates inflammatory responses in lipopolysaccharide-induced neural stem cells by regulating NF-κB and phosphorylation of p38-MAPKs pathways
- (2016) Wei Zhu et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Mesencephalic Astrocyte-Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress-Related Kidney Diseases
- (2016) Y. Kim et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cerebral dopamine neurotrophic factor alleviates Aβ 25-35 -induced endoplasmic reticulum stress and early synaptotoxicity in rat hippocampal cells
- (2016) Wei Zhou et al. NEUROSCIENCE LETTERS
- Immune modulation by MANF promotes tissue repair and regenerative success in the retina
- (2016) J. Neves et al. SCIENCE
- Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson’s Disease
- (2016) Enrique Garea-Rodríguez et al. PLoS One
- Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes
- (2016) Emilia Galli et al. Scientific Reports
- Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
- (2015) Susanna Kemppainen et al. BEHAVIOURAL BRAIN RESEARCH
- Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease
- (2015) Merja H. Voutilainen et al. FEBS LETTERS
- ER stress-inducible protein MANF selectively expresses in human spleen
- (2015) Jun Liu et al. HUMAN IMMUNOLOGY
- The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers
- (2015) Cristiane Latge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhanced Efficacy of the CDNF/MANF Family by Combined Intranigral Overexpression in the 6-OHDA Rat Model of Parkinson's Disease
- (2015) Óscar Cordero-Llana et al. MOLECULAR THERAPY
- Tunicamycin-induced unfolded protein response in the developing mouse brain
- (2015) Haiping Wang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity
- (2015) K Mätlik et al. Cell Death & Disease
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Involved in Inflammation by Negatively Regulating the NF-κB Pathway
- (2015) Lijian Chen et al. Scientific Reports
- Deficiency of IRE1 and PERK Signal Pathways in Systemic Lupus Erythematosus
- (2014) Qiyao Cheng et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
- (2014) Rasajna Nadella et al. Journal of Neuroinflammation
- Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis
- (2014) Wen Yang et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis
- (2014) Mark J. Henderson et al. MOLECULAR BIOLOGY OF THE CELL
- Proteostasis in endoplasmic reticulum—new mechanisms in kidney disease
- (2014) Reiko Inagi et al. Nature Reviews Nephrology
- Conserved Dopamine Neurotrophic Factor-Transduced Mesenchymal Stem Cells Promote Axon Regeneration and Functional Recovery of Injured Sciatic Nerve
- (2014) Yi Liu et al. PLoS One
- MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells
- (2014) Maria Lindahl et al. Cell Reports
- Overexpression of conserved dopamine neurotrophic factor (CDNF) in astrocytes alleviates endoplasmic reticulum stress-induced cell damage and inflammatory cytokine secretion
- (2013) Lei Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model
- (2013) Xinmiao Ren et al. EXPERIMENTAL NEUROLOGY
- Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases
- (2013) Claire L. Hartley et al. HUMAN MOLECULAR GENETICS
- UPR Signal Activation by Luminal Sensor Domains
- (2013) Marta Carrara et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Inhibits Oxygen–Glucose Deprivation-Induced Cell Damage and Inflammation by Suppressing Endoplasmic Reticulum Stress in Rat Primary Astrocytes
- (2013) Hua Zhao et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Mechanisms of Anti-inflammatory Property of Conserved Dopamine Neurotrophic Factor: Inhibition of JNK Signaling in Lipopolysaccharide-Induced Microglia
- (2013) Hua Zhao et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
- (2013) Riitta Lindström et al. PLoS One
- Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
- (2013) Matthew D. Shoulders et al. Cell Reports
- Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease
- (2013) Susanne Bäck et al. Brain and Behavior
- 1H-, 13C- and 15N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF)
- (2012) Cristiane Latgé et al. Biomolecular NMR Assignments
- Gene expression analysis of Drosophila Manf mutants reveals perturbations in membrane traffic and major metabolic changes
- (2012) Mari Palgi et al. BMC GENOMICS
- Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors
- (2012) Mark J. Henderson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion
- (2012) Christopher C. Glembotski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation
- (2012) Yujun Shen et al. Journal of Neuroinflammation
- CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery after MPTP Treatment in Mice
- (2011) Mikko Airavaara et al. CELL TRANSPLANTATION
- Intracellular trafficking and secretion of mouse mesencephalic astrocyte-derived neurotrophic factor
- (2011) Kentaro Oh-hashi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Transcriptional Profiling of Chondrodysplasia Growth Plate Cartilage Reveals Adaptive ER-Stress Networks That Allow Survival but Disrupt Hypertrophy
- (2011) Trevor L. Cameron et al. PLoS One
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction
- (2011) Esteban N. Gurzov et al. TRENDS IN CELL BIOLOGY
- 1H, 13C and 15N resonance assignments of the human mesencephalic astrocyte-derived neurotrophic factor
- (2010) Maarit Hellman et al. Biomolecular NMR Assignments
- An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia
- (2010) Seema Nundlall et al. CELL STRESS & CHAPERONES
- Widespread cortical expression of MANF by AAV serotype 7: Localization and protection against ischemic brain injury
- (2010) Mikko Airavaara et al. EXPERIMENTAL NEUROLOGY
- Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
- (2010) Merja H. Voutilainen et al. EXPERIMENTAL NEUROLOGY
- Induction Profile of MANF/ARMET by Cerebral Ischemia and its Implication for Neuron Protection
- (2009) Yong-Qiang Yu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats
- (2009) Mikko Airavaara et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease
- (2009) M. H. Voutilainen et al. JOURNAL OF NEUROSCIENCE
- The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
- (2009) Vimal Parkash et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart
- (2008) Archana Tadimalla et al. CIRCULATION RESEARCH
- Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
- (2008) A APOSTOLOU et al. EXPERIMENTAL CELL RESEARCH
- MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain
- (2008) Päivi Lindholm et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The human PDI family: Versatility packed into a single fold
- (2007) Christian Appenzeller-Herzog et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More