The rich pharmacological activities of Magnolia officinalis and secondary effects based on significant intestinal contributions

Sirtuin 3 Activation by Honokiol Decreases Unilateral Ureteral Obstruction-Induced Renal Inflammation and Fibrosis via Regulation of Mitochondrial Dynamics and the Renal NF-κB-TGF-β1/Smad Signaling Pathway

(2020) Yi Quan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Traditional Chinese Medicine for COVID-19 Treatment

(2020) Jun-ling Ren et al.   PHARMACOLOGICAL RESEARCH

Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo

(2020) Gauthami Pulivendala et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Suppression of PKCδ/NF-κB Signaling and Apoptosis Induction through Extrinsic/Intrinsic Pathways Are Associated with Magnolol-Inhibited Tumor Progression in Colorectal Cancer In Vitro and In Vivo

(2020) Chun-Min Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The potential insights of Traditional Chinese Medicine on treatment of COVID-19

(2020) Tong Tong et al.   Chinese Medicine

Accelerated, severe lupus nephritis benefits from treatment with honokiol by immunoregulation and differentially regulating NF‐κB/NLRP3 inflammasome and sirtuin 1/autophagy axis

(2020) Shin‐Ruen Yang et al.   FASEB JOURNAL

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

(2020) Dâmaris Silveira et al.   Frontiers in Pharmacology

Honokiol Protects the Kidney from Renal Ischemia and Reperfusion Injury by Upregulating the Glutathione Biosynthetic Enzymes

(2020) Eun Jung Park et al.   Biomedicines

Inhibition of Herpes Simplex Virus-1 Replication by Natural Compound Honokiol

(2019) Shuai Liu et al.   VIROLOGICA SINICA

Protective effect of magnolol on oxaliplatin-induced intestinal injury in mice

(2019) Ting Xia et al.   PHYTOTHERAPY RESEARCH

Obesity: global epidemiology and pathogenesis

(2019) Matthias Blüher   Nature Reviews Endocrinology

Honokiol induces endoplasmic reticulum stress-mediated apoptosis in human lung cancer cells

(2019) Jianfei Zhu et al.   LIFE SCIENCES

Honokiol Attenuates Sepsis-Associated Acute Kidney Injury via the Inhibition of Oxidative Stress and Inflammation

(2019) Shilin Xia et al.   INFLAMMATION

Honokiol Improves Insulin Resistance, Hepatic Steatosis, and Inflammation in Type 2 Diabetic db/db Mice

(2019) Young-Je Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A review of the phytochemistry and pharmacological activities of Magnoliae officinalis cortex

(2019) Hanyan Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model

(2019) Bo Zhang et al.   MOLECULES

The Protective Effect of Magnolol in Osteoarthritis: In vitro and in vivo Studies

(2019) Zhi-Chao Hu et al.   Frontiers in Pharmacology

Metabolism, Obesity, and Diabetes Mellitus

(2019) Henry H. Ruiz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Suppression of TRPV1 and P2Y nociceptors by honokiol isolated from Magnolia officinalis in 3rd degree burn mice by inhibiting inflammatory mediators

(2019) Sidra Khalid et al.   BIOMEDICINE & PHARMACOTHERAPY

Magmenthanes A-H: Eight new meroterpenoids from the bark of Magnolia officinalis var. Biloba

(2019) Chuan Li et al.   BIOORGANIC CHEMISTRY

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets

(2019) Kishore Banik et al.   PHARMACOLOGICAL RESEARCH

Magnolol inhibits growth and induces apoptosis in esophagus cancer KYSE-150 cell lines via the MAP kinase pathway

(2019) Yu Chen et al.   Journal of Thoracic Disease

Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKKβ pathways

(2019) Tzyy-Bin Tsay et al.   Journal of Translational Medicine

An orally administered magnoloside A ameliorates functional dyspepsia by modulating brain-gut peptides and gut microbiota

(2019) Zhenzhen Xue et al.   LIFE SCIENCES

Honokiol, magnolol and its monoacetyl derivative show strong anti-fungal effect on Fusarium isolates of clinical relevance

(2019) Safa Oufensou et al.   PLoS One

Mechanisms controlling hormone secretion in human gut and its relevance to metabolism

(2019) Alyce M Martin et al.   JOURNAL OF ENDOCRINOLOGY

Baicalin Protects Against Hypertension-Associated Intestinal Barrier Impairment in Part Through Enhanced Microbial Production of Short-Chain Fatty Acids

(2019) Dandan Wu et al.   Frontiers in Pharmacology

Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosis

(2019) Hung-Ting Liu et al.   Antioxidants

Honokiol Ameliorates High-Fat-Diet-Induced Obesity of Different Sexes of Mice by Modulating the Composition of the Gut Microbiota

(2019) Yanan Ding et al.   Frontiers in Immunology

Honokiol: A Review of Its Anticancer Potential and Mechanisms

(2019) Chon Phin Ong et al.   Cancers

Serotonergic regulation of insulin secretion

(2018) L. R. Cataldo Bascuñan et al.   Acta Physiologica

Honokiol protects pancreatic β cell against high glucose and intermittent hypoxia-induced injury by activating Nrf2/ARE pathway in vitro and in vivo

(2018) Chen-guang Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

(2018) Allison Agus et al.   Cell Host & Microbe

Atherosclerosis and inflammation: overview and updates

(2018) Glaucylara Reis Geovanini et al.   CLINICAL SCIENCE

Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy

(2018) Kao-Jean Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Enhancement of oral bioavailability of magnolol by encapsulation in mixed micelles containing pluronic F127 and L61

(2018) Hongxue Shen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Magnolol treatment attenuates dextran sulphate sodium-induced murine experimental colitis by regulating inflammation and mucosal damage

(2018) Peng Shen et al.   LIFE SCIENCES

Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

(2018) Chul-Hwan Lee et al.   MOLECULAR CELL

Magterpenoids A–C, Three Polycyclic Meroterpenoids with PTP1B Inhibitory Activity from the Bark of Magnolia officinalis var. biloba

(2018) Chuan Li et al.   ORGANIC LETTERS

Potent anti-inflammatory effects of honokiol in human fetal membranes and myometrium

(2018) Yasaswi Kaumadha Wijesuriya et al.   PHYTOMEDICINE

Safety and Toxicology of Magnolol and Honokiol

(2018) Andrea Sarrica et al.   PLANTA MEDICA

Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice

(2018) Chun-Kai Chang et al.   PLoS One

Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling

(2018) Sidra Khalid et al.   Frontiers in Pharmacology

Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation

(2018) Ye Tian et al.   Frontiers in Immunology

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome

(2018) Jane M. Natividad et al.   Cell Metabolism

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer

(2018) Abhishek Ranaware et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries

(2018) Margaret E Kruk et al.   LANCET

Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS partially via the Sirt3/AMPK signaling axis

(2018) Lan Chen et al.   LIFE SCIENCES

Improved oral bioavailability of magnolol by using a binary mixed micelle system

(2018) Pinggang Ding et al.   Artificial Cells Nanomedicine and Biotechnology

Magnolol ameliorates pneumonectomy and monocrotaline-induced pulmonary arterial hypertension in rats through inhibition of angiotensin II and endothelin-1 expression

(2018) Hung Chang et al.   PHYTOMEDICINE

Da-Cheng-Qi Decoction Combined with Conventional Treatment for Treating Postsurgical Gastrointestinal Dysfunction

(2017) Wei Jin et al.   Evidence-based Complementary and Alternative Medicine

Mechanisms of curcumin-induced gastroprotection against ethanol-induced gastric mucosal lesions

(2017) Renata Czekaj et al.   JOURNAL OF GASTROENTEROLOGY

Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota

(2017) Jun Xu et al.   MEDICINAL RESEARCH REVIEWS

The natural compound magnolol affects growth, biofilm formation, and ultrastructure of oral Candida isolates

(2017) Jawad Behbehani et al.   MICROBIAL PATHOGENESIS

Beneficial effect of magnolol on lupus nephritis in MRL/lpr mice by attenuating the NLRP3 inflammasome and NF-κB signaling pathway: A mechanistic analysis

(2017) Feng Huang et al.   Molecular Medicine Reports

Magnolol, a Natural Polyphenol, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice

(2017) Ling Zhao et al.   MOLECULES

Inhibitory Effects of Honokiol on the Voltage-Gated Potassium Channels in Freshly Isolated Mouse Dorsal Root Ganglion Neurons

(2017) Anqi Sheng et al.   NEUROCHEMICAL RESEARCH

Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells

(2017) Chieh-Hsiang Lu et al.   PHARMACOLOGICAL RESEARCH

Obesity and hypertension

(2017) Gino Seravalle et al.   PHARMACOLOGICAL RESEARCH

In vitro inhibitory activities of magnolol against Candida spp.

(2017) Peiru Zhou et al.   Drug Design Development and Therapy

Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts

(2017) Lizhen Huang et al.   Scientific Reports

Magnolol inhibits venous remodeling in mice

(2017) Hanna Kuk et al.   Scientific Reports

Magnolia officinalis L. Fortified Gum Improves Resistance of Oral Epithelial Cells Against Inflammation

(2016) Jessica Walker et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon

(2016) Ying Xia et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease

(2016) William Herrington et al.   CIRCULATION RESEARCH

Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum

(2016) Hsiao-Jou Cortina Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1

(2016) Samuel Bertin et al.   GUT

TRPA1, substance P, histamine and 5-hydroxytryptamine interact in an interdependent way to induce nociception

(2016) Luana Fischer et al.   INFLAMMATION RESEARCH

Anti-biofilm and bactericidal effects of magnolia bark-derived magnolol and honokiol on Streptococcus mutans

(2016) Yuuki Sakaue et al.   MICROBIOLOGY AND IMMUNOLOGY

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats

(2016) Honglin Sun et al.   Obesity Facts

The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

(2016) Karolina Pytka et al.   Pharmacological Reports

Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer

(2016) Yuting Liu et al.   PHARMACOLOGICAL RESEARCH

Antifibrotic Therapies: Where Are We Now?

(2016) Young Yoon et al.   SEMINARS IN LIVER DISEASE

Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment

(2015) Samira Goldar et al.   Asian Pacific Journal of Cancer Prevention

In vitro synergism of magnolol and honokiol in combination with antibacterial agents against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA)

(2015) Guo-Ying Zuo et al.   BMC Complementary and Alternative Medicine

Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway

(2015) Maolan Li et al.   CANCER SCIENCE

The cytokines of pulmonary fibrosis: Much learned, much more to learn

(2015) Irina G. Luzina et al.   CYTOKINE

Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice

(2015) Yanli Deng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inflammation and clinical response to treatment in depression: A meta-analysis

(2015) R. Strawbridge et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Honokiol, magnolol, and a combination of both compounds improve glucose metabolism in high-fat diet-induced obese mice

(2015) Young-Sil Lee et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-kB activation

(2015) Ming-Hsien Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Magnolia Bioactive Constituent 4-O-Methylhonokiol Prevents the Impairment of Cardiac Insulin Signaling and the Cardiac Pathogenesis in High-Fat Diet-Induced Obese Mice

(2015) Zhiguo Zhang et al.   International Journal of Biological Sciences

Honokiol for the Treatment of Neonatal Pain and Prevention of Consequent Neurobehavioral Disorders

(2015) Anna Woodbury et al.   JOURNAL OF NATURAL PRODUCTS

Antioxidant Activity of Magnolol and Honokiol: Kinetic and Mechanistic Investigations of Their Reaction with Peroxyl Radicals

(2015) Riccardo Amorati et al.   JOURNAL OF ORGANIC CHEMISTRY

Vasoactive intestinal peptide is a local mediator in a gut-brain neural axis activating intestinal gluconeogenesis

(2015) F. De Vadder et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effects of Magnolol and Honokiol on Adhesion, Yeast-Hyphal Transition, and Formation of Biofilm by Candida albicans

(2015) Lingmei Sun et al.   PLoS One

Honokiol, a Lignan Biphenol Derived from the Magnolia Tree, Inhibits Dengue Virus Type 2 Infection

(2015) Chih-Yeu Fang et al.   Viruses-Basel

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Anti-Obesity and Anti-Hyperglycemic Effects of Cinnamaldehyde via altered Ghrelin Secretion and Functional impact on Food Intake and Gastric Emptying

(2015) Susana Camacho et al.   Scientific Reports

Magnolia officinalisExtract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

(2015) Jing Sun et al.   Biomed Research International

Magnolol Administration in Normotensive Young Spontaneously Hypertensive Rats Postpones the Development of Hypertension: Role of Increased PPAR Gamma, Reduced TRB3 and Resultant Alleviative Vascular Insulin Resistance

(2015) Xiangyan Liang et al.   PLoS One

Magnolol Reduced TNF-α-Induced Vascular Cell Adhesion Molecule-1 Expression in Endothelial Cells via JNK/p38 and NF-κB Signaling Pathways

(2014) Chan-Jung Liang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Non-coronary atherosclerosis

(2014) A. Gallino et al.   EUROPEAN HEART JOURNAL

Role of magnolol in the proliferation of vascular smooth muscle cells

(2014) L. Wu et al.   HERZ

Magnolol Inhibits Tumor Necrosis Factor-α-Induced ICAM-1 Expression via Suppressing NF-κB And MAPK Signaling Pathways in Human Lung Epithelial Cells

(2014) Wu Chunlian et al.   INFLAMMATION

Effects of Honokiol on Sepsis-Induced Acute Kidney Injury in an Experimental Model of Sepsis in Rats

(2014) Nan Li et al.   INFLAMMATION

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

MagnoliaExtract (BL153) Protection of Heart from Lipid Accumulation Caused Cardiac Oxidative Damage, Inflammation, and Cell Death in High-Fat Diet Fed Mice

(2014) Weixia Sun et al.   Oxidative Medicine and Cellular Longevity

BL153 Partially Prevents High-Fat Diet Induced Liver Damage Probably via Inhibition of Lipid Accumulation, Inflammation, and Oxidative Stress

(2014) Jian Wang et al.   Oxidative Medicine and Cellular Longevity

TheMagnoliaBioactive Constituent 4-O-Methylhonokiol Protects against High-Fat Diet-Induced Obesity and Systemic Insulin Resistance in Mice

(2014) Zhiguo Zhang et al.   Oxidative Medicine and Cellular Longevity

Neuroprotective glucosides of magnolol and honokiol from microbial-specific glycosylation

(2014) Lin Yang et al.   TETRAHEDRON

Apoptosis and Molecular Targeting Therapy in Cancer

(2014) Mohamed Hassan et al.   Biomed Research International

The effect of exogenous GLP-1 on food intake is lost in male truncally vagotomized subjects with pyloroplasty

(2013) Astrid Plamboeck et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Magnolol inhibits migration of vascular smooth muscle cells via cytoskeletal remodeling pathway to attenuate neointima formation

(2013) Rajendra Karki et al.   EXPERIMENTAL CELL RESEARCH

Magnolol Pretreatment Prevents Sepsis-Induced Intestinal Dysmotility by Maintaining Functional Interstitial Cells of Cajal

(2013) Bin Miao et al.   INFLAMMATION

Pharmacokinetic and Pharmacodynamic Studies of Four Major Phytochemical Components of Da-Cheng-Qi Decoction to Treat Acute Pancreatitis

(2013) Jianlei Zhao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice

(2013) Young-Je Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats

(2013) Man Zhang et al.   PHYTOMEDICINE

Mitochondrial DNA Damage and Dysfunction, and Oxidative Stress Are Associated with Endoplasmic Reticulum Stress, Protein Degradation and Apoptosis in High Fat Diet-Induced Insulin Resistance Mice

(2013) Larysa V. Yuzefovych et al.   PLoS One

The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy

(2013) Ying Liu et al.   Scientific Reports

The antiplatelet activity of magnolol is mediated by PPAR-β/γ

(2012) Ching-Yu Shih et al.   BIOCHEMICAL PHARMACOLOGY

Magnolol attenuates neointima formation by inducing cell cycle arrest via inhibition of ERK1/2 and NF-κB activation in vascular smooth muscle cells

(2012) Rajendra Karki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity

(2012) NJ Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

The absorption and transport of magnolol in Caco-2 cell model

(2012) An-guo Wu et al.   Chinese Journal of Integrative Medicine

Piecewise nonlinear mixed-effects models for modeling cardiac function and assessing treatment effects

(2012) Hyejeong Jang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Protective Effect of Magnolol on Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2012) Yun Feng Ni et al.   INFLAMMATION

Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways

(2012) Yunhe Fu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Apoptosis-inducing and Antitumor Activity of Neolignans Isolated fromMagnolia officinalisin HeLa Cancer Cells

(2012) Ui Joung Youn et al.   PHYTOTHERAPY RESEARCH

Calpain/SHP-1 Interaction by Honokiol Dampening Peritoneal Dissemination of Gastric Cancer in nu/nu Mice

(2012) Shing Hwa Liu et al.   PLoS One

Honokiol Attenuates Torsion/Detorsion-induced Testicular Injury in Rat Testis by Way of Suppressing Endoplasmic Reticulum Stress-related Apoptosis

(2012) Kuo-How Huang et al.   UROLOGY

Potent and selective inhibition of magnolol on catalytic activities of UGT1A7 and 1A9

(2012) Liangliang Zhu et al.   XENOBIOTICA

Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55

(2012) Viktor Rempel et al.   ACS Medicinal Chemistry Letters

Comparison of antioxidant abilities of magnolol and honokiol to scavenge radicals and to protect DNA

(2011) Chao Zhao et al.   BIOCHIMIE

Effects of magnolol on UVB-induced skin cancer development in mice and its possible mechanism of action

(2011) Chandeshwari Chilampalli et al.   BMC CANCER

Glutamate NMDA receptor dysregulation in Parkinson’s disease with dyskinesias

(2011) Imtiaz Ahmed et al.   BRAIN

Honokiol ameliorates renal fibrosis by inhibiting extracellular matrix and pro-inflammatory factors in vivo and in vitro

(2011) Chih-Kang Chiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antimetastatic activity of honokiol in osteosarcoma

(2011) Patrick Steinmann et al.   CANCER

Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells

(2011) Chandeshwari Chilampalli et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Modulation of GABAA-Receptors by Honokiol and Derivatives: Subtype Selectivity and Structure–Activity Relationship

(2011) Barbara Taferner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Honokiol produces anti-neoplastic effects on melanoma cells in vitro

(2011) Patrick W. Mannal et al.   JOURNAL OF SURGICAL ONCOLOGY

Magnolol Attenuates the Lung Injury in Hypertonic Saline Treatment from Mesenteric Ischemia Reperfusion through Diminishing iNOS

(2011) Hsin-Chin Shih et al.   JOURNAL OF SURGICAL RESEARCH

Antimicrobial effect of Magnolia officinaliss extract against Staphylococcus aureus

(2011) Yongjin Hu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Multiple effects of honokiol on the life cycle of hepatitis C virus

(2011) Keng-Hsin Lan et al.   LIVER INTERNATIONAL

Pharmacokinetics, Bioavailability, and Tissue Distribution of Magnolol Following Single and Repeated Dosing of Magnolol to Rats

(2011) Shiuan-Pey Lin et al.   PLANTA MEDICA

Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ

(2011) Haitao Zhang et al.   PLoS One

Increased expression of bFGF is associated with carotid atherosclerotic plaques instability engaging the NF-κB pathway

(2010) Fragiska Sigala et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Interleukin-1β induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of ERK, JNK, AP-1, and NF-κB

(2010) Chuen-Mao Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protective effect of a polyphenolic rich extract from Magnolia officinalis bark on influenza virus-induced pneumonia in mice

(2010) Xiao-ning Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-Inflammatory Effects of the Neurotransmitter Agonist Honokiol in a Mouse Model of Allergic Asthma

(2010) M. E. Munroe et al.   JOURNAL OF IMMUNOLOGY

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells

(2010) Chu Peng Hoi et al.   PHYTOTHERAPY RESEARCH

The Expanded Biology of Serotonin

(2009) Miles Berger et al.   Annual Review of Medicine

Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats

(2009) Li-Qin Qiang et al.   ARCHIVES OF PHARMACAL RESEARCH

Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats

(2009) Yung-Hsiang Chen et al.   ARCHIVES OF PHARMACAL RESEARCH

Antiplatelet Actions of Statins and Fibrates Are Mediated by PPARs

(2009) Ferhana Y. Ali et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Anti-gastritic Effects of Magnolol and Honokiol from the Stem Bark of Magnolia obovata

(2009) So-Yean Cho et al.   Biomolecules & Therapeutics

Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice

(2009) Nobuaki Matsui et al.   BRAIN RESEARCH

Magnolol Inhibits Human Glioblastoma Cell Proliferation through Upregulation of p21/Cip1

(2009) Li-Ching Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells

(2009) Sun-Sil Choi et al.   LIFE SCIENCES

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833

(2009) Bing Hu et al.   PAIN

Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice

(2009) Li-Tao Yi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Synergistic and additive actions of a psychosocial stressor and endotoxin challenge: Circulating and brain cytokines, plasma corticosterone and behavioral changes in mice

(2008) Julie Gibb et al.   BRAIN BEHAVIOR AND IMMUNITY

Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-κB, JNK and p38 MAPK inactivation

(2008) Hong Yu Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain

(2008) A Akbar et al.   GUT

Regulation of contractile activity by magnolol in the rat isolated gastrointestinal tracts

(2008) Seung Il Jeong et al.   PHARMACOLOGICAL RESEARCH

Inhibitory effects of the aqueous extract ofMagnolia officinalison the responses of human urinary bladder cancer 5637 cellsin vitroand mouse urinary bladder tumors induced byN-Butyl-N-(4-hydroxybutyl) nitrosaminein vivo

(2008) Se-Jung Lee et al.   PHYTOTHERAPY RESEARCH

Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents

(2007) Qun Xu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY