Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model

Safety and Toxicology of Magnolol and Honokiol

(2018) Andrea Sarrica et al.   PLANTA MEDICA

Calcium-Dependent Desensitization of NMDA Receptors

(2018) D. A. Sibarov et al.   BIOCHEMISTRY-MOSCOW

The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders

(2017) Yajin Liao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents

(2017) Mélanie Poivre et al.   Journal of Zhejiang University-SCIENCE B

Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis

(2017) Cristiano A. Köhler et al.   MOLECULAR NEUROBIOLOGY

Cancer Chemoprevention by Phytochemicals: Nature’s Healing Touch

(2017) Haseeb Zubair et al.   MOLECULES

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

(2017) Michael D. Lovelace et al.   NEUROPHARMACOLOGY

Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice

(2016) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

New in vitro insights on a cell death pathway induced by magnolol and honokiol in aristolochic acid tubulotoxicity

(2016) Valérian Bunel et al.   FOOD AND CHEMICAL TOXICOLOGY

Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum

(2016) Hsiao-Jou Cortina Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Preclinical effects of honokiol on treating glioblastoma multiforme via G1 phase arrest and cell apoptosis

(2016) Chien-Ju Lin et al.   PHYTOMEDICINE

Inflammation and clinical response to treatment in depression: A meta-analysis

(2015) R. Strawbridge et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice

(2015) Kunjbihari Sulakhiya et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder

(2015) Christoph U. Correll et al.   World Psychiatry

Cytokines, prostaglandins and nitric oxide in the regulation of stress-response systems

(2014) Anna Gądek-Michalska et al.   Pharmacological Reports

Does tryptophan degradation along the kynurenine pathway mediate the association between pro-inflammatory immune activity and depressive symptoms?

(2014) Jacqueline Quak et al.   PSYCHONEUROENDOCRINOLOGY

IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase

(2013) Ling Ye et al.   JOURNAL OF NEUROCHEMISTRY

Network beyond IDO in psychiatric disorders: Revisiting neurodegeneration hypothesis

(2013) Aye-Mu Myint et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway

(2012) J.-W. Lin et al.   NEURO-ONCOLOGY

Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells

(2012) Peng Zhang et al.   NEUROSCIENCE LETTERS

Depressive-like behavior induced by tumor necrosis factor-α in mice

(2011) Manuella P. Kaster et al.   NEUROPHARMACOLOGY

The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis

(2011) Jonas Hannestad et al.   NEUROPSYCHOPHARMACOLOGY

Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways

(2011) Ching-Shu Lai et al.   Journal of Functional Foods

Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophan-kynurenine metabolism

(2010) Gregory F. Oxenkrug   Annals of the New York Academy of Sciences

The pharmacological properties of antidepressants

(2010) Giorgio Racagni et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

The possible role of the kynurenine pathway in adolescent depression with melancholic features

(2010) Vilma Gabbay et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Honokiol and Magnolol as Multifunctional Antioxidative Molecules for Dermatologic Disorders

(2010) Jui-Lung Shen et al.   MOLECULES

Nuclear factor- B is a critical mediator of stress-impaired neurogenesis and depressive behavior

(2010) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression

(2009) Byung Hun Kim et al.   ACTA PHARMACOLOGICA SINICA

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

Calcium Pumps in Health and Disease

(2009) Marisa Brini et al.   PHYSIOLOGICAL REVIEWS

Indoleamine 2,3-dioxygenase activation and depressive symptoms in patients with coronary artery disease

(2009) Walter Swardfager et al.   PSYCHONEUROENDOCRINOLOGY

Honokiol is a potent scavenger of superoxide and peroxyl radicals

(2008) Sergey Dikalov et al.   BIOCHEMICAL PHARMACOLOGY

Synergistic and additive actions of a psychosocial stressor and endotoxin challenge: Circulating and brain cytokines, plasma corticosterone and behavioral changes in mice

(2008) Julie Gibb et al.   BRAIN BEHAVIOR AND IMMUNITY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer

(2008) Hongyu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE