Mesenchymal Stem Cells and Extracellular Vesicles in Osteosarcoma Pathogenesis and Therapy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mesenchymal Stem Cells and Extracellular Vesicles in Osteosarcoma Pathogenesis and Therapy
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 20, Pages 11035
Publisher
MDPI AG
Online
2021-10-14
DOI
10.3390/ijms222011035
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Bone Marrow Mesenchymal Stem Cells-Derived Extracellular Vesicles Promote Proliferation, Invasion and Migration of Osteosarcoma Cells via the lncRNA MALAT1/miR-143/NRSN2/Wnt/β-Catenin Axis
- (2021) Fujiang Li et al. OncoTargets and Therapy
- Combination immunotherapy using G-CSF and oncolytic virotherapy reduces tumor growth in osteosarcoma
- (2021) Alvaro Morales-Molina et al. Journal for ImmunoTherapy of Cancer
- Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: “alliance” or “war” in intercellular signals
- (2021) Noemi Eiro et al. Cell and Bioscience
- New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma
- (2021) Xingyu Chang et al. Journal of Bone Oncology
- M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages
- (2021) Gowri Rangaswamy Gunassekaran et al. BIOMATERIALS
- Stem Cells in Tumour Microenvironment Aids for Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment
- (2020) Bhaskar Birru et al. CURRENT DRUG METABOLISM
- Mesenchymal stromal cells mediated delivery of photoactive nanoparticles inhibits osteosarcoma growth in vitro and in a murine in vivo ectopic model
- (2020) Stefania Lenna et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors
- (2020) David Ruano et al. MOLECULAR THERAPY
- The biology, function, and biomedical applications of exosomes
- (2020) Raghu Kalluri et al. SCIENCE
- Conditioned Medium of the Osteosarcoma Cell Line U2OS Induces hBMSCs to Exhibit Characteristics of Carcinoma-Associated Fibroblasts via Activation of IL-6/STAT3 Signaling
- (2020) Longshuai Lin et al. JOURNAL OF BIOCHEMISTRY
- The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem
- (2020) Isabelle Corre et al. Cells
- Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression
- (2020) Yan Wang et al. Frontiers in Cell and Developmental Biology
- Exosomes derived from bone marrow mesenchymal stem cells promote osteosarcoma development by activating oncogenic autophagy
- (2020) Yao Huang et al. Journal of Bone Oncology
- Tumor-Associated Macrophages in Osteosarcoma: From Mechanisms to Therapy
- (2020) Francesca Cersosimo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Bone marrow mesenchymal stem cell-derived exosomal miR-206 inhibits osteosarcoma progression by targeting TRA2B
- (2020) Hongliang Zhang et al. CANCER LETTERS
- Mesenchymal stem cell-derived exosomes carrying microRNA-150 suppresses the proliferation and migration of osteosarcoma cells via targeting IGF2BP1
- (2020) Zhengfeng Xu et al. Translational Cancer Research
- Macrophages in Osteosarcoma Immune Microenvironment: Implications for Immunotherapy
- (2020) Zhong-Wei Luo et al. Frontiers in Oncology
- Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles
- (2019) Bettina Mannerström et al. Epigenetics
- Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation
- (2019) Megan R. Showalter et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Exosome-Mediated Metastasis: Communication from a Distance
- (2019) Inbal Wortzel et al. DEVELOPMENTAL CELL
- Inhibition of M2-like macrophages by all-trans retinoic acid prevents cancer initiation and stemness in osteosarcoma cells
- (2019) Xue-jing Shao et al. ACTA PHARMACOLOGICA SINICA
- Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs
- (2019) Lavinia Raimondi et al. CARCINOGENESIS
- Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis
- (2019) Wen-Ching Shen et al. Nature Communications
- Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling
- (2019) Raquel Batlle et al. Nature Communications
- Extracellular Nanovesicles Secreted by Human Osteosarcoma Cells Promote Angiogenesis
- (2019) Francesca Perut et al. Cancers
- Long non-coding RNA PVT1 encapsulated in bone marrow mesenchymal stem cell-derived exosomes promotes osteosarcoma growth and metastasis by stabilizing ERG and sponging miR-183-5p
- (2019) Wei Zhao et al. Aging-US
- Bone marrow‐derived mesenchymal stem cell‐derived exosomal microRNA‐208a promotes osteosarcoma cell proliferation, migration, and invasion
- (2019) Fa Qin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids
- (2018) Daphne L. van der Velden et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment
- (2018) Masanori Kawano et al. Cell Communication and Signaling
- Exosomes originating from MSCs stimulated with TGF-β and IFN-γ promote Treg differentiation
- (2018) Qingyi Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition
- (2018) Laura Pietrovito et al. Molecular Oncology
- Sox2 is required for tumor development and cancer cell proliferation in osteosarcoma
- (2018) Giulia Maurizi et al. ONCOGENE
- CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis
- (2018) Lin Du et al. Cell Death & Disease
- Interaction between mesenchymal stromal cell-derived extracellular vesicles and immune cells by distinct protein content
- (2018) Soura Mardpour et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Microvesicles derived from human bone marrow mesenchymal stem cells promote U2OS cell growth under hypoxia: the role of PI3K/AKT and HIF-1α
- (2018) Shanshan Lin et al. Human Cell
- Mesenchymal Stromal Cell-Derived Exosomes Affect mRNA Expression and Function of B-Lymphocytes
- (2018) Drirh Khare et al. Frontiers in Immunology
- Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
- (2017) Sofia Avnet et al. INTERNATIONAL JOURNAL OF CANCER
- Exosomes: Key mediators of metastasis and pre-metastatic niche formation
- (2017) Richard J. Lobb et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Hypoxia Inducible Factor-1α Potentiates Jagged 1-Mediated Angiogenesis by Mesenchymal Stem Cell-Derived Exosomes
- (2017) Hernán Gonzalez-King et al. STEM CELLS
- Human adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting
- (2017) Francesca Paino et al. Cell Death & Disease
- Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis
- (2017) Min Gong et al. Oncotarget
- Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway
- (2017) Yan Wang et al. Oncotarget
- Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
- (2016) Rashmi Bharti et al. CANCER LETTERS
- Proton-sensing GPCR-YAP Signalling Promotes Cancer-associated Fibroblast Activation of Mesenchymal Stem Cells
- (2016) Hongyi Zhu et al. International Journal of Biological Sciences
- Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
- (2016) Margherita Cortini et al. PLoS One
- Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects
- (2016) Xiao-hua Jia et al. Oncotarget
- Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3
- (2016) Bing Tu et al. Oncotarget
- Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones
- (2016) Rebecca Macklin et al. Oncotarget
- Generation of Osteosarcomas from a Combination of Rb Silencing and c-Myc Overexpression in Human Mesenchymal Stem Cells
- (2016) Jir-You Wang et al. Stem Cells Translational Medicine
- Harnessing the Angiogenic Potential of Stem Cell-Derived Exosomes for Vascular Regeneration
- (2016) F. Alcayaga-Miranda et al. Stem Cells International
- Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies
- (2016) Ander Abarrategi et al. Stem Cells International
- Mesenchymal Stem/Stromal Cells under Stress Increase Osteosarcoma Migration and Apoptosis Resistance via Extracellular Vesicle Mediated Communication
- (2016) Krishna C. Vallabhaneni et al. PLoS One
- Do Mesenchymal Stromal Cells Influence Microscopic Residual or Metastatic Osteosarcoma in a Murine Model?
- (2015) Megan E. Aanstoos et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Effect of local treatment with adipose tissue-derived mesenchymal stem cells in the early tumorigenesis of osteosarcoma
- (2015) SHEEN-WOO LEE et al. ONCOLOGY REPORTS
- Mesenchymal Progenitors Expressing TRAIL Induce Apoptosis in Sarcomas
- (2015) Giulia Grisendi et al. STEM CELLS
- Mesenchymal stem cells promote tumor angiogenesis via the action of transforming growth factor β1
- (2015) GUO-CAI LI et al. Oncology Letters
- Human mesenchymal stem cells as delivery of osteoprotegerin gene: homing and therapeutic effect for osteosarcoma
- (2015) Bo Qiao et al. Drug Design Development and Therapy
- Cells of origin in osteosarcoma: Mesenchymal stem cells or osteoblast committed cells?
- (2014) Anthony J. Mutsaers et al. BONE
- Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis
- (2014) Ivy A. W. Ho et al. FASEB JOURNAL
- The roles of mesenchymal stem cells in tumor inflammatory microenvironment
- (2014) Zhao Sun et al. Journal of Hematology & Oncology
- Exosomes Derived from Mesenchymal Stem Cells Suppress Angiogenesis by Down-Regulating VEGF Expression in Breast Cancer Cells
- (2014) Jong-Kuen Lee et al. PLoS One
- Role of Signaling Pathways in Mesenchymal Stem Cell Differentiation
- (2014) Birru Bhaskar et al. Current Stem Cell Research & Therapy
- Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-β/Smad2/3 pathway
- (2013) Bing Tu et al. EXPERIMENTAL CELL RESEARCH
- Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
- (2013) Pallavi Chaturvedi et al. JOURNAL OF CLINICAL INVESTIGATION
- Mesenchymal stem cells as delivery vehicle of porphyrin loaded nanoparticles: Effective photoinduced in vitro killing of osteosarcoma
- (2013) S. Duchi et al. JOURNAL OF CONTROLLED RELEASE
- CXCR4-mediated osteosarcoma growth and pulmonary metastasis is promoted by mesenchymal stem cells through VEGF
- (2013) PENG ZHANG et al. ONCOLOGY REPORTS
- WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition
- (2013) Vickie Y. Jo et al. PATHOLOGY
- Mesenchymal Stem Cells Secrete Immunologically Active Exosomes
- (2013) Bin Zhang et al. STEM CELLS AND DEVELOPMENT
- Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2012) ANNALS OF ONCOLOGY
- STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma
- (2012) Bing Tu et al. CANCER LETTERS
- Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
- (2012) Guanglei Zhuang et al. EMBO JOURNAL
- TheMEToncogene transforms human primary bone-derived cells into osteosarcomas by targeting committed osteo-progenitors
- (2012) Nadia Dani et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Human umbilical cord wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro
- (2012) Kalamegam Gauthaman et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development
- (2012) R Rubio et al. ONCOGENE
- Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
- (2011) Jeanine M.L. Roodhart et al. CANCER CELL
- Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo
- (2011) Wei Zhu et al. CANCER LETTERS
- TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells
- (2011) Shuanhu Zhou JOURNAL OF CELLULAR BIOCHEMISTRY
- Human mesenchymal stem cells promote growth of osteosarcoma: Involvement of interleukin-6 in the interaction between human mesenchymal stem cells and Saos-2
- (2010) Zhen-Yu Bian et al. CANCER SCIENCE
- Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications
- (2010) Soufiane Ghannam et al. Stem Cell Research & Therapy
- Osteosarcoma incidence and survival rates from 1973 to 2004
- (2009) Lisa Mirabello et al. CANCER
- Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis
- (2009) Wen-ting Xu et al. CANCER LETTERS
- Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss ofCdkn2
- (2009) Alexander B Mohseny et al. JOURNAL OF PATHOLOGY
- Murine bone marrow-derived mesenchymal stem cells as vehicles for interleukin-12 gene delivery into Ewing sarcoma tumors
- (2008) Xiaoping Duan et al. CANCER
- Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
- (2008) C. R. Walkley et al. GENES & DEVELOPMENT
- Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Mediate Human Stem Cell Tropism to Malignant Solid Tumors
- (2008) Margarita Gutova et al. STEM CELLS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation