CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis
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Title
CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis
Authors
Keywords
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Journal
Cell Death & Disease
Volume 9, Issue 7, Pages -
Publisher
Springer Nature
Online
2018-06-18
DOI
10.1038/s41419-018-0745-0
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Note: Only part of the references are listed.- Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
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- CXCR1 knockdown improves the sensitivity of osteosarcoma to cisplatin
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- Osteosarcoma
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- Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis
- (2009) Wen-ting Xu et al. CANCER LETTERS
- The PKB/AKT Pathway in Cancer
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- Primary Osteogenic Sarcoma with Pulmonary Metastasis: Clinical Results and Prognostic Factors in 91 Patients
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- Anoikis resistance and tumor metastasis
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- The Interleukin-8 Pathway in Cancer
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- The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase
- (2008) Sachie Hiratsuka et al. NATURE CELL BIOLOGY
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