Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression

(2012) Yuan-Guo Wang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mixed lineage kinase 3 is required for matrix metalloproteinase expression and invasion in ovarian cancer cells

(2012) Yu Zhan et al.   EXPERIMENTAL CELL RESEARCH

The transmembrane chemokines CXCL16 and CX3CL1 and their receptors are expressed in human meningiomas

(2012) GU LI et al.   ONCOLOGY REPORTS

CXCR7/CXCR4 Heterodimer Constitutively Recruits β-Arrestin to Enhance Cell Migration

(2011) Fabien M. Décaillot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Chemoattractive Factors Involved in the Migration of Bone Marrow-Derived Mesenchymal Stem Cells to Brain Lesions Caused by Prions

(2011) C.-H. Song et al.   JOURNAL OF VIROLOGY

Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

(2011) Seok-Jun Kim et al.   PLoS One

Concise Review: Mesenchymal Stem Cell Tumor-Homing: Detection Methods in Disease Model Systems

(2011) Michaela R. Reagan et al.   STEM CELLS

Mesenchymal Stem Cells Overexpressing CXCR4 Attenuate Remodeling of Postmyocardial Infarction by Releasing Matrix Metalloproteinase-9

(2011) Wei Huang et al.   STEM CELLS AND DEVELOPMENT

Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt, ERK, and p38 signal transduction pathways

(2010) Chung Heon Ryu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CXCR4 and matrix metalloproteinase-2 are involved in mesenchymal stromal cell homing and engraftment to tumors

(2010) Chao Song et al.   CYTOTHERAPY

CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression

(2010) Xiaojuan Sun et al.   Molecular Cancer

SDF-1α as a therapeutic stem cell homing factor in myocardial infarction

(2010) Santhosh K. Ghadge et al.   PHARMACOLOGY & THERAPEUTICS

Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis

(2010) K. S. Carbajal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model

(2009) Toshiyuki Kitaori et al.   ARTHRITIS AND RHEUMATISM

Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis by Activating PAR1 at a Cryptic Ligand Site

(2009) Vishal Trivedi et al.   CELL

Activation of toll-like receptors 2, 3 or 5 induces matrix metalloproteinase-1 and -9 expression with the involvement of MAPKs and NF-κB in human epidermal keratinocytes

(2009) Youngae Lee et al.   EXPERIMENTAL DERMATOLOGY

Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dose-dependent manner resulting in increased susceptibility of BCR-ABL+cell to Imatinib and Nilotinib

(2009) Falk Dillmann et al.   LEUKEMIA & LYMPHOMA

CXCR4 and CXCR7 cooperate during tangential migration of facial motoneurons

(2009) Nicolas Cubedo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma-Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells

(2009) S. M. Eck et al.   MOLECULAR CANCER RESEARCH

A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

(2009) J S Blackburn et al.   ONCOGENE

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

(2009) L. S. Sasportas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix Metalloproteinase 1 Is Necessary for the Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Human Glioma

(2009) Ivy A. W. Ho et al.   STEM CELLS

SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model

(2008) Ye Wang et al.   BRAIN RESEARCH

HSV-1 amplicon viral vector-mediated gene transfer to human bone marrow-derived mesenchymal stem cells

(2008) I A W Ho et al.   CANCER GENE THERAPY

Mesenchymal Stem Cells Effectively Deliver an Oncolytic Adenovirus to Intracranial Glioma

(2008) Adam M. Sonabend et al.   STEM CELLS