Astilbin ameliorates oxidative stress and apoptosis in D-galactose-induced senescence by regulating the PI3K/Akt/m-TOR signaling pathway in the brains of mice

Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice

(2020) Xin Li et al.   Clinical Interventions in Aging

Polyphenols as Caloric-Restriction Mimetics and Autophagy Inducers in Aging Research

(2020) Assylzhan Yessenkyzy et al.   Nutrients

Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish

(2020) Mounir El Maï et al.   eLife

Shikonin ameliorates D-galactose-induced oxidative stress and cognitive impairment in mice via the MAPK and nuclear factor-κB signaling pathway

(2020) Junjie Zhong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

ASTILBIN: A PROMISING UNEXPLORED COMPOUND WITH MULTIDIMENSIONAL MEDICINAL AND HEALTH BENEFITS

(2020) Abhishek Sharma et al.   PHARMACOLOGICAL RESEARCH

Preventive effect of small‐leaved Kuding tea ( Ligustrum robustum ) on high‐diet‐induced obesity in C57BL/6J mice

(2020) Ya Wu et al.   Food Science & Nutrition

Partially saturated canthaxanthin alleviates aging-associated oxidative stress in d-galactose administered male wistar rats

(2020) Ahila Mathimaran et al.   BIOGERONTOLOGY

Protective effects of Coreopsis tinctoria buds extract against cognitive impairment and brain aging induced by d-galactose

(2020) Xiaoqin He et al.   Journal of Functional Foods

Protective effect of walnut on d ‐galactose‐induced aging mouse model

(2019) Ji Liu et al.   Food Science & Nutrition

Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence

(2019) Bo Liu et al.   NEUROCHEMICAL RESEARCH

Effects of Guilingji on Aging Rats and Its Underlying Mechanisms

(2019) Si-jun Zhao et al.   REJUVENATION RESEARCH

l-histidine and l-carnosine accelerate wound healing via regulation of corticosterone and PI3K/Akt phosphorylation in d-galactose-induced aging models in vitro and in vivo

(2019) Yerin Kim et al.   Journal of Functional Foods

Reactive Oxygen Species as Potential Drivers of the Seed Aging Process

(2019) Katarzyna Kurek et al.   Plants-Basel

d-Galactose-induced accelerated aging model: an overview

(2019) Khairunnuur Fairuz Azman et al.   BIOGERONTOLOGY

Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice

(2019) Ji-yue Sha et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates d-Galactose-Induced Brain Aging in Mice

(2019) Peng Chen et al.   Neurotherapeutics

Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor (BDNF)

(2019) Eman Y. Khairy et al.   NUTRITIONAL NEUROSCIENCE

The effect of a glyphosate-based herbicide on acetylcholinesterase (AChE) activity, oxidative stress, and antioxidant status in freshwater amphipod: Gammarus pulex (Crustacean)

(2019) Ayşegül Pala   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effect of Ginkgo biloba Extract EGb761 on Hippocampal Neuronal Injury and Carbonyl Stress of D-show="" $132#?=""Gal-Induced Aging Rats

(2019) Juan Li et al.   Evidence-based Complementary and Alternative Medicine

Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability

(2019) Liyang Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lycium barbarum polysaccharide protects against oxygen glucose deprivation/reoxygenation-induced apoptosis and autophagic cell death via the PI3K/Akt/mTOR signaling pathway in primary cultured hippocampal neurons

(2018) Yang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Onjisaponin B prevents cognitive impairment in a rat model of D -galactose-induced aging

(2018) Gaowen Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Smilax aristolochiifolia Root Extract and Its Compounds Chlorogenic Acid and Astilbin Inhibit the Activity of α-Amylase and α-Glucosidase Enzymes

(2018) Viridiana Candelaria Pérez-Nájera et al.   Evidence-based Complementary and Alternative Medicine

20( R )-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis

(2018) Yan-dan Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Astilbin Inhibits High Glucose-Induced Inflammation and Extracellular Matrix Accumulation by Suppressing the TLR4/MyD88/NF-κB Pathway in Rat Glomerular Mesangial Cells

(2018) Fang Chen et al.   Frontiers in Pharmacology

Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway

(2017) Bing Han et al.   PHYTOMEDICINE

Post-translational Modification of Caspases: The Other Side of Apoptosis Regulation

(2017) Alexey V. Zamaraev et al.   TRENDS IN CELL BIOLOGY

Brain Aging: Uncovering Cortical Characteristics of Healthy Aging in Young Adults

(2017) Sahil Bajaj et al.   Frontiers in Aging Neuroscience

Ethnic and diet-related differences in the healthy infant microbiome

(2017) Jennifer C. Stearns et al.   Genome Medicine

Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats

(2016) Josiane Budni et al.   BEHAVIOURAL BRAIN RESEARCH

Anthocyanins Reversed D-Galactose-Induced Oxidative Stress and Neuroinflammation Mediated Cognitive Impairment in Adult Rats

(2016) Shafiq Ur Rehman et al.   MOLECULAR NEUROBIOLOGY

Allicin inhibits oxidative stress-induced mitochondrial dysfunction and apoptosis by promoting PI3K/AKT and CREB/ERK signaling in osteoblast cells

(2016) GUOLIANG DING et al.   Experimental and Therapeutic Medicine

Fibroblast growth factor 21 protects mouse brain against d-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation

(2015) Yinhang Yu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Significance of apoptosis related proteins on malignant transformation of ovarian tumors: A comparison between Bcl-2/Bax ratio and p53 immunoreactivity

(2014) Tamer Zeren et al.   ACTA HISTOCHEMICA

Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice

(2014) Chen Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginsenoside Rb1 improves postoperative fatigue syndrome by reducing skeletal muscle oxidative stress through activation of the PI3K/Akt/Nrf2 pathway in aged rats

(2014) Cheng-Le Zhuang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of Akt/mTOR Attenuates Age-Related Changes in Mesenchymal Stem Cells

(2014) Borzo Gharibi et al.   STEM CELLS

Mussel oligopeptides ameliorate cognition deficit and attenuate brain senescence in d-galactose-induced aging mice

(2013) Yue Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Regulation and Function of Autophagy during Cell Survival and Cell Death

(2012) G. Das et al.   Cold Spring Harbor Perspectives in Biology

Isolation and Characterization of Two Flavonoids, Engeletin and Astilbin, from the Leaves of Engelhardia roxburghiana and Their Potential Anti-inflammatory Properties

(2011) Haiqiu Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Aging, frailty and age-related diseases

(2010) T. Fulop et al.   BIOGERONTOLOGY

Acetaminophen reduces mitochondrial dysfunction during early cerebral postischemic reperfusion in rats

(2010) Sunanda S. Baliga et al.   BRAIN RESEARCH

Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging?

(2009) Adam B. Salmon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant activity of Rhizoma Smilacis Glabrae extracts and its key constituent-astilbin

(2008) Qing-Feng Zhang et al.   FOOD CHEMISTRY