Overview of a bioremediation tool: organophosphorus hydrolase and its significant application in the food, environmental, and therapy fields

In-depth biochemical identification of a novel methyl parathion hydrolase from Azohydromonas australica and its high effectiveness in the degradation of various organophosphorus pesticides

(2021) Sumao Zhao et al.   BIORESOURCE TECHNOLOGY

Engineering organophosphate hydrolase for enhanced biocatalytic performance: A review

(2021) Lijie Wang et al.   BIOCHEMICAL ENGINEERING JOURNAL

Roles and applications of enzymes for resistant pollutants removal in wastewater treatment

(2021) Siran Feng et al.   BIORESOURCE TECHNOLOGY

Catalytic and structural effects of flexible loop deletion in organophosphorus hydrolase enzyme: A thermostability improvement mechanism

(2020) Gholamreza Farnoosh et al.   JOURNAL OF BIOSCIENCES

Biodegradation of organophosphorus insecticides by two organophosphorus hydrolase genes (opdA and opdE) from isolated Leuconostoc mesenteroides WCP307 of kimchi origin

(2020) Azizul Md. Haque et al.   PROCESS BIOCHEMISTRY

Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents

(2019) Peng Zhang et al.   Science Translational Medicine

A newly emerging trend of chitosan-based sensing platform for the organophosphate pesticide detection using Acetylcholinesterase- a review

(2019) Hitika Patel et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Advances in detection of hazardous organophosphorus compounds using organophosphorus hydrolase based biosensors

(2019) Monika Jain et al.   CRITICAL REVIEWS IN TOXICOLOGY

Organophosphate hydrolase conjugated UiO-66-NH2 MOF based highly sensitive optical detection of methyl parathion

(2019) Jyotsana Mehta et al.   ENVIRONMENTAL RESEARCH

The evolution of phosphotriesterase for decontamination and detoxification of organophosphorus chemical warfare agents

(2019) Andrew N. Bigley et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Efficacy of an organophosphorus hydrolase enzyme (OpdA) in human serum and minipig models of organophosphorus insecticide poisoning

(2019) Michael Eddleston et al.   CLINICAL TOXICOLOGY

Microbial Phosphotriesterase: Structure, Function, and Biotechnological Applications

(2019) Wahhida Latip et al.   Catalysts

Simple Purification and Immobilization of His-Tagged Organophosphohydrolase from Cell Culture Supernatant by Metal Organic Frameworks for Degradation of Organophosphorus Pesticides

(2019) Saiguang Xue et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Enzymatic Bioremediation of Organophosphate Compounds—Progress and Remaining Challenges

(2019) Meghna Thakur et al.   Frontiers in Bioengineering and Biotechnology

A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds

(2019) Laura Job et al.   TOXICOLOGY LETTERS

Ozone as a novel emerging technology for the dissipation of pesticide residues in foods–a review

(2019) R. Pandiselvam et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Identifying and engineering a critical amino acid residue to enhance the catalytic efficiency of Pseudomonas sp. methyl parathion hydrolase

(2018) Yingnan Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Mechanisms of acetylcholinesterase protection against sarin and soman by adenosine A 1 receptor agonist N 6 -cyclopentyladenosine

(2018) Ariana Beste et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Biodegradation of organophosphorus insecticides with P S bonds by two Sphingobium sp. strains

(2018) Jae-Hyung Ahn et al.   INTERNATIONAL BIODETERIORATION & BIODEGRADATION

Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

(2018) Adi Goldenzweig et al.   MOLECULAR CELL

Covalent immobilization of organophosphorus hydrolase enzyme on chemically modified cellulose microfibers: Statistical optimization and characterization

(2018) Meisam Sharifi et al.   REACTIVE & FUNCTIONAL POLYMERS

Detection of oxidative stress and DNA damage in freshwater snail Lymnea leuteola exposed to profenofos

(2018) Daoud Ali et al.   Frontiers of Environmental Science & Engineering

Organophosphorus hydrolase-poly-β-cyclodextrin as a stable self-decontaminating bio-catalytic material for sorption and degradation of organophosphate pesticide

(2018) Youngkwang Moon et al.   JOURNAL OF HAZARDOUS MATERIALS

Efficient Degradation of Malathion in the Presence of Detergents Using an Engineered Organophosphorus Hydrolase Highly Expressed by Pichia pastoris without Methanol Induction

(2017) Yun-Peng Bai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers

(2017) Moshe Goldsmith et al.   PROTEIN ENGINEERING DESIGN & SELECTION

High-level extracellular secretion of organophosphorous hydrolase ofFlavobacteriumsp. inEscherichia coliBL21(DE3)pLysS

(2016) Soudeh Khanamani Falahati-Pour et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Organophosphate-degrading metallohydrolases: Structure and function of potent catalysts for applications in bioremediation

(2016) Gerhard Schenk et al.   COORDINATION CHEMISTRY REVIEWS

Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes

(2016) Pauline Jacquet et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Engineering and introduction of de novo disulphide bridges in organophosphorus hydrolase enzyme for thermostability improvement

(2016) Gholamreza Farnoosh et al.   JOURNAL OF BIOSCIENCES

High level expression of organophosphorus hydrolase in Pichia pastoris by multicopy ophcM assembly

(2016) Wei Shen et al.   PROTEIN EXPRESSION AND PURIFICATION

Recent approaches to improving selectivity and sensitivity of enzyme-based biosensors for organophosphorus pesticides: A review

(2016) Everlyne A. Songa et al.   TALANTA

Biosensor based on electrospun blended chitosan-poly (vinyl alcohol) nanofibrous enzymatically sensitized membranes for pirimiphos-methyl detection in olive oil

(2016) A.Y. El-Moghazy et al.   TALANTA

Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection

(2016) Timo Wille et al.   TOXICOLOGY LETTERS

Enzymatic technologies for remediation of hydrophobic organic pollutants in soil

(2015) G. Eibes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro

(2015) Moshe Goldsmith et al.   ARCHIVES OF TOXICOLOGY

In VivoSelf-Assembly of Stable Green Fluorescent Protein Fusion Particles and Their Uses in Enzyme Immobilization

(2014) Mark Venning-Slater et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rational design of organophosphorus hydrolase with high catalytic efficiency for detoxifying a V-type nerve agent

(2014) Young-Su Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp

(2014) Xiao-Jing Luo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Improved Stability and Half-Life of Fluorinated Phosphotriesterase Using Rosetta

(2014) Ching-Yao Yang et al.   CHEMBIOCHEM

Cloning and expression of ophB gene encoding organophosphorus hydrolase from endophytic Pseudomonas sp. BF1-3 degrades organophosphorus pesticide chlorpyrifos

(2014) Dhirendra Nath Barman et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH)

(2014) Marcelo M. Pedroso et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis

(2014) Tatheer Naqvi et al.   PLoS One

Expression pattern of recombinant organophosphorus hydrolase from Flavobacterium sp. ATCC 27551 in Escherichia coli

(2012) Yunyoung Kwak et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improving the thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 using a computationally aided method

(2012) Jian Tian et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Hydrolysis of organophosphorus pesticides in soil: New opportunities with ecocompatible immobilized His6-OPH

(2012) M. Sirotkina et al.   INTERNATIONAL BIODETERIORATION & BIODEGRADATION

High-throughput screening system based on phenolics-responsive transcription activator for directed evolution of organophosphate-degrading enzymes

(2012) Y.-S. Jeong et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Enhanced Refoldability and Thermoactivity of Fluorinated Phosphotriesterase

(2011) Peter James Baker et al.   CHEMBIOCHEM

Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA)

(2011) Fernanda Ely et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents

(2011) Marie Trovaslet-Leroy et al.   TOXICOLOGY LETTERS

An intramolecular disulfide bond is required for the thermostability of methyl parathion hydrolase, OPHC2

(2010) Xiao-yu Chu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The organophosphate-degrading enzyme fromAgrobacterium radiobacterdisplays mechanistic flexibility for catalysis

(2010) Fernanda Ely et al.   BIOCHEMICAL JOURNAL

Pharmacokinetics of OpdA, an organophosphorus hydrolase, in the African green monkey

(2010) Colin J. Jackson et al.   BIOCHEMICAL PHARMACOLOGY

Review on the use of enzymes for the detection of organochlorine, organophosphate and carbamate pesticides in the environment

(2010) J. Susan Van Dyk et al.   CHEMOSPHERE

Twin-Arginine Translocation of Methyl Parathion Hydrolase inBacillus subtilis

(2010) Chao Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation

(2010) Jian Tian et al.   FEBS Journal

Organophosphorus Hydrolase (OpdB) of Lactobacillus brevis WCP902 from Kimchi Is Able To Degrade Organophosphorus Pesticides

(2010) Shah Md. Asraful Islam et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Generation of a mutagenized organophosphorus hydrolase for the biodegradation of the organophosphate pesticides malathion and demeton-S

(2010) D.A. Schofield et al.   JOURNAL OF APPLIED MICROBIOLOGY

A free-enzyme catalyst for the bioremediation of environmental atrazine contamination

(2010) Colin Scott et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Structure-Based Rational Design of a Phosphotriesterase

(2009) C. J. Jackson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structure-Based and Random Mutagenesis Approaches Increase the Organophosphate-Degrading Activity of a Phosphotriesterase Homologue from Deinococcus radiodurans

(2009) Renda Hawwa et al.   JOURNAL OF MOLECULAR BIOLOGY

Soil genomics

(2009) Brajesh K. Singh et al.   NATURE REVIEWS MICROBIOLOGY

Overexpression of methyl parathion hydrolase and its application in detoxification of organophosphates

(2008) Jijian Yang et al.   BIODEGRADATION

Impact assessment of pesticide residues in fish of Ganga river around Kolkata in West Bengal

(2008) Md. Wasim Aktar et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Functional Assembly of a Microbial Consortium with Autofluorescent and Mineralizing Activity for the Biodegradation of Organophosphates

(2008) Heng Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Degradation of nerve agents by an organophosphate-degrading agent (OpdA)

(2008) R.M. Dawson et al.   JOURNAL OF HAZARDOUS MATERIALS

In Crystallo Capture of a Michaelis Complex and Product-binding Modes of a Bacterial Phosphotriesterase

(2007) Colin J. Jackson et al.   JOURNAL OF MOLECULAR BIOLOGY