Microbial Phosphotriesterase: Structure, Function, and Biotechnological Applications

Printed Graphene Electrochemical Biosensors Fabricated by Inkjet Maskless Lithography for Rapid and Sensitive Detection of Organophosphates

(2018) John A. Hondred et al.   ACS Applied Materials & Interfaces

The Effect of N-Terminal Domain Removal towards the Biochemical and Structural Features of a Thermotolerant Lipase from an Antarctic Pseudomonas sp. Strain AMS3

(2018) Wahhida Latip et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enzymatic detoxification: a sustainable means of degrading toxic organophosphate pesticides and chemical warfare nerve agents

(2018) Giuseppe Manco et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Enzymatic detoxification of organophosphorus pesticides and related toxicants

(2018) Karla Alejo-González et al.   JOURNAL OF PESTICIDE SCIENCE

Microbial Degradation of Organophosphate Pesticides: A Review

(2018) Shardendu KUMAR et al.   PEDOSPHERE

Innovative Biocatalysts as Tools to Detect and Inactivate Nerve Agents

(2018) Elena Porzio et al.   Scientific Reports

Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase

(2017) Pauline Jacquet et al.   Scientific Reports

Molecular Docking, Metal Substitution and Hydrolysis Reaction of Chiral Substrates of Phosphotriesterase

(2016) Alexandre A. de Castro et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Development of a Biosensor Based on Phosphotriesterase and n-Channel ISFET for Detection of Pesticides

(2016) M. S. Andrianova et al.   ELECTROANALYSIS

Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

(2016) Andrew N. Bigley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organophosphate-Hydrolyzing Enzymes as First-Line of Defence Against Nerve Agent-Poisoning: Perspectives and the Road Ahead

(2016) A. R. Satvik Iyengar et al.   PROTEIN JOURNAL

Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection

(2016) Timo Wille et al.   TOXICOLOGY LETTERS

Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR

(2015) Andrew N. Bigley et al.   BIOCHEMISTRY

An efficient thermostable organophosphate hydrolase and its application in pesticide decontamination

(2015) Immacolata Del Giudice et al.   BIOTECHNOLOGY AND BIOENGINEERING

Rational design of organophosphorus hydrolase with high catalytic efficiency for detoxifying a V-type nerve agent

(2014) Young-Su Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH)

(2014) Marcelo M. Pedroso et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Progress in the development of enzyme-based nerve agent bioscavengers

(2013) Florian Nachon et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis

(2013) Andrew N. Bigley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and Enzymatic Characterization of the Phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenes

(2013) Guillaume Gotthard et al.   PLoS One

Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents

(2012) Ping-Chuan Tsai et al.   BIOCHEMISTRY

A colorimetric assay for determination of methyl parathion using recombinant methyl parathion hydrolase

(2011) Dau Hung Anh et al.   Biotechnology Journal

Hydrolysis of organophosphorus compounds by microbial enzymes

(2010) Casey M. Theriot et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structural Determinants for the Stereoselective Hydrolysis of Chiral Substrates by Phosphotriesterase

(2010) Ping-Chuan Tsai et al.   BIOCHEMISTRY

Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus

(2009) Renda Hawwa et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Structural Insights into the Dual Activities of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase

(2009) Nand K. Vyas et al.   BIOCHEMISTRY

Biosensor-controlled degradation of chlorpyrifos and chlorfenvinfos using a phosphotriesterase-based detoxification column

(2009) Georges Istamboulie et al.   CHEMOSPHERE

Update on biochemical properties of recombinantPseudomonas diminutaphosphotriesterase

(2009) Eugénie Carletti et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Organophosphorus-degrading bacteria: ecology and industrial applications

(2008) Brajesh K. Singh   NATURE REVIEWS MICROBIOLOGY

Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities

(2008) T.E. Reeves et al.   PROTEIN ENGINEERING DESIGN & SELECTION