Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling
Authors
Keywords
Mutant huntingtin, Mitochondria, Respiration, Calcium uptake, Permeability transition pore
Journal
MOLECULAR NEUROBIOLOGY
Volume 53, Issue 5, Pages 2944-2953
Publisher
Springer Nature
Online
2015-05-04
DOI
10.1007/s12035-015-9188-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain
- (2014) N. K. H. Lim et al. HUMAN MOLECULAR GENETICS
- Impaired Brain Energy Metabolism in the BACHD Mouse Model of Huntington's Disease: Critical Role of Astrocyte–Neuron Interactions
- (2014) Lydie Boussicault et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Inhibition of mitochondrial protein import by mutant huntingtin
- (2014) Hiroko Yano et al. NATURE NEUROSCIENCE
- A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
- (2013) Maria Damiano et al. HUMAN MOLECULAR GENETICS
- Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease
- (2013) Rodrigo A Quintanilla et al. Molecular Neurodegeneration
- Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease
- (2013) Caroline Gouarné et al. PLoS One
- Mitochondrial DNA damage Is associated with reduced mitochondrial bioenergetics in Huntington's disease
- (2012) Almas Siddiqui et al. FREE RADICAL BIOLOGY AND MEDICINE
- Defective mitochondrial disulfide relay system, altered mitochondrial morphology and function in Huntington's disease
- (2012) Eleonora Napoli et al. HUMAN MOLECULAR GENETICS
- Dysregulation of Mitochondrial Calcium Signaling and Superoxide Flashes Cause Mitochondrial Genomic DNA Damage in Huntington Disease
- (2012) Jiu-Qiang Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Homeostatic Adaptations in Brain Energy Metabolism in Mouse Models of Huntington Disease
- (2012) Ivan Tkac et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A Novel BACHD Transgenic Rat Exhibits Characteristic Neuropathological Features of Huntington Disease
- (2012) L. Yu-Taeger et al. JOURNAL OF NEUROSCIENCE
- Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
- (2011) U. Shirendeb et al. HUMAN MOLECULAR GENETICS
- Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
- (2011) U. P. Shirendeb et al. HUMAN MOLECULAR GENETICS
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
- (2011) Wenjun Song et al. NATURE MEDICINE
- Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli
- (2010) Veronica Costa et al. EMBO Molecular Medicine
- Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease
- (2010) Giselle M. Perry et al. HUMAN MOLECULAR GENETICS
- Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
- (2010) J. Kim et al. HUMAN MOLECULAR GENETICS
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
- (2010) Chiara Zuccato et al. PHYSIOLOGICAL REVIEWS
- The metabolic profile of early Huntington's disease- a combined human and transgenic mouse study
- (2008) Anna O.G. Goodman et al. EXPERIMENTAL NEUROLOGY
- Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice
- (2008) Judit Oláh et al. FEBS Journal
- Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse
- (2008) T. B. Brown et al. HUMAN MOLECULAR GENETICS
- Impaired Regulation of Brain Mitochondria by Extramitochondrial Ca2+in Transgenic Huntington Disease Rats
- (2008) Frank N. Gellerich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice
- (2008) M. Gray et al. JOURNAL OF NEUROSCIENCE
- N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking
- (2008) A. L. Orr et al. JOURNAL OF NEUROSCIENCE
- Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease
- (2008) Hua Zhang et al. NEUROBIOLOGY OF DISEASE
- Rodent genetic models of Huntington disease
- (2008) Mary Y. Heng et al. NEUROBIOLOGY OF DISEASE
- Increased metabolism in the R6/2 mouse model of Huntington’s disease
- (2007) Jorien M.M. van der Burg et al. NEUROBIOLOGY OF DISEASE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started