Antioxidant and bioenergetic coupling between neurons and astrocytes

Antioxidants in Central Nervous System Diseases: Preclinical Promise and Translational Challenges

(2017) Chandrashekhar D. Kamat et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses

(2011) Aude Panatier et al.   CELL

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

Levodopa Activates Apoptosis Signaling Kinase 1 (ASK1) and Promotes Apoptosis in a Neuronal Model: Implications for the Treatment of Parkinson's Disease

(2011) Elizabeth A. Sabens Liedhegner et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioenergetic dysfunction in Huntington's disease human cybrids

(2011) I. Luisa Ferreira et al.   EXPERIMENTAL NEUROLOGY

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lactate Transport and Metabolism in the Human Brain: Implications for the Astrocyte-Neuron Lactate Shuttle Hypothesis

(2011) C. R. Figley   JOURNAL OF NEUROSCIENCE

Fast and Reversible Stimulation of Astrocytic Glycolysis by K+ and a Delayed and Persistent Effect of Glutamate

(2011) C. X. Bittner et al.   JOURNAL OF NEUROSCIENCE

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Alterations in glutathione S-transferase pi expression following exposure to MPP+-induced oxidative stress in the blood of Parkinson’s disease patients

(2011) Ane Korff et al.   PARKINSONISM & RELATED DISORDERS

Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis

(2011) P. Diaz-Amarilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons

(2010) Manuel Garrido et al.   ACTA NEUROPATHOLOGICA

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

A Comparison of Thiol Peroxidase Mechanisms

(2010) Leopold Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Neuronal Oxidative and Nitrosative Stress by Endogenous Protective Pathways and Disease Processes

(2010) Giles E. Hardingham et al.   ANTIOXIDANTS & REDOX SIGNALING

Levodopa Deactivates Enzymes That Regulate Thiol−Disulfide Homeostasis and Promotes Neuronal Cell Death: Implications for Therapy of Parkinson’s Disease

(2010) Elizabeth A. Sabens et al.   BIOCHEMISTRY

Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease

(2010) Shankar J. Chinta et al.   FREE RADICAL RESEARCH

Should the word ‘dementia’ be forgotten?

(2010) Kurt A. Jellinger   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Vitamin E, Ascorbate, Glutathione, Glutathicne Disulfide, and Enzymes of Glutathione Metabolism in Cultures of Chick Astrocytes and Neurons: Evidence that Astrocytes Play an Important Role in Antioxidative Processes in the Brain

(2010) Tapas K. Makar et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons

(2010) Guy C. Brown et al.   MOLECULAR NEUROBIOLOGY

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

(2010) K. F. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

(2010) R. E. Haskew-Layton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications☆

(2009) Juan P. Bolaños et al.   ADVANCED DRUG DELIVERY REVIEWS

A Disruption in Iron-Sulfur Center Biogenesis via Inhibition of Mitochondrial Dithiol Glutaredoxin 2 May Contribute to Mitochondrial and Cellular Iron Dysregulation in Mammalian Glutathione-Depleted Dopaminergic Cells: Implications for Parkinson's Disease

(2009) Donna W. Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking

(2009) Johannes Hirrlinger et al.   BRAIN RESEARCH REVIEWS

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Simultaneous single neuron recording of O2consumption, [Ca2+]iand mitochondrial membrane potential in glutamate toxicity

(2009) Marc Gleichmann et al.   JOURNAL OF NEUROCHEMISTRY

Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure

(2009) Sung W. Choi et al.   JOURNAL OF NEUROCHEMISTRY

Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity

(2009) Arvind Shakya et al.   NATURE CELL BIOLOGY

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review

(2008) M. M. C. Wamelink et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Role of retinal glial cells in neurotransmitter uptake and metabolism

(2008) Andreas Bringmann et al.   NEUROCHEMISTRY INTERNATIONAL

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Neurobiology and treatment of Parkinson's disease

(2008) Anthony H.V. Schapira   TRENDS IN PHARMACOLOGICAL SCIENCES