Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks

Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake

(2021) Kevin D. Hall et al.   NATURE MEDICINE

Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data

(2021) Joshua Z Goldenberg et al.   BMJ-British Medical Journal

Response: Commentary: Consumer Reports of “Keto Flu” Associated With the Ketogenic Diet

(2021) Emmanuelle C. S. Bostock et al.   Frontiers in Nutrition

Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes

(2020) Rainer J. Klement et al.   MEDICAL ONCOLOGY

Resistant Starch Content in Foods Commonly Consumed in the United States: A Narrative Review

(2020) Mindy A. Patterson et al.   Journal of the Academy of Nutrition and Dietetics

Association of Low-Carbohydrate and Low-Fat Diets With Mortality Among US Adults

(2020) Zhilei Shan et al.   JAMA Internal Medicine

A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise

(2020) Ida A. Heikura et al.   Frontiers in Endocrinology

Are ketogenic diets promising for Alzheimer’s disease? A translational review

(2020) Matthieu Lilamand et al.   Alzheimers Research & Therapy

The Effect of Low-Fat and Low-Carbohydrate Diets on Weight Loss and Lipid Levels: A Systematic Review and Meta-Analysis

(2020) Shreya Chawla et al.   Nutrients

Effect of the ketogenic diet on glycemic control, insulin resistance, and lipid metabolism in patients with T2DM: a systematic review and meta-analysis

(2020) Xiaojie Yuan et al.   Nutrition & Diabetes

Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)

(2019) Dariusz Włodarek   Nutrients

The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy

(2019) Marie Lindefeldt et al.   npj Biofilms and Microbiomes

Ketogenic Diet and Epilepsy: What We Know So Far

(2019) Isabella D’Andrea Meira et al.   Frontiers in Neuroscience

Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: an open-label, non-randomised controlled study

(2019) Eduardo Vilar-Gomez et al.   BMJ Open

Impact of Nutritional Changes on Nonalcoholic Fatty Liver Disease

(2019) Carolina M. Perdomo et al.   Nutrients

Dietary patterns and abnormal glucose tolerance among Japanese: findings from the National Health and Nutrition Survey, 2012

(2019) Emiko Okada et al.   PUBLIC HEALTH NUTRITION

Oxidative Stress and Antioxidant Biomarkers in Clinical and Experimental Models of Non-Alcoholic Fatty Liver Disease

(2019) Ayokanmi Ore et al.   Medicina-Lithuania

Women's periconceptional lowered carbohydrate intake and NTD-affected pregnancy risk in the era of prefortification with folic acid

(2019) Gary M. Shaw et al.   Birth Defects Research

A ketogenic diet for reducing obesity and maintaining capacity for physical activity

(2019) E. Angela Murphy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet

(2019) Michael Rosenbaum et al.   Obesity

Association Between Plant-Based Dietary Patterns and Risk of Type 2 Diabetes

(2019) Frank Qian et al.   JAMA Internal Medicine

The Ketogenic Diet for Obesity and Diabetes—Enthusiasm Outpaces Evidence

(2019) Shivam Joshi et al.   JAMA Internal Medicine

Ketogenic Diet and Microbiota: Friends or Enemies?

(2019) Antonio Paoli et al.   Genes

Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial

(2019) Shaminie J. Athinarayanan et al.   Frontiers in Endocrinology

Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force

(2019) C.F. Kirkpatrick et al.   Journal of Clinical Lipidology

A Prospective Study of Dietary Meat Intake and Risk of Incident Chronic Kidney Disease

(2019) Parvin Mirmiran et al.   JOURNAL OF RENAL NUTRITION

Unintended pregnancy and interpregnancy interval by maternal age, National Survey of Family Growth

(2018) Katherine A. Ahrens et al.   CONTRACEPTION

The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia

(2018) Z. Z. X. Leow et al.   DIABETIC MEDICINE

Overweight and diabetes prevention: is a low-carbohydrate–high-fat diet recommendable?

(2018) Fred Brouns   EUROPEAN JOURNAL OF NUTRITION

Pattern of polyphenol intake and the long-term risk of dementia in older persons

(2018) Sophie Lefèvre-Arbogast et al.   NEUROLOGY

Risk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses

(2018) Vanesa Bellou et al.   PLoS One

Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study

(2018) Sarah J. Hallberg et al.   Diabetes Therapy

Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study

(2018) Sarah J. Hallberg et al.   Diabetes Therapy

Low carbohydrate diets may increase risk of neural tube defects

(2018) Tania A. Desrosiers et al.   Birth Defects Research

Low-carbohydrate-diet score and risk of type 2 diabetes in women

(2018) Thomas L Halton et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Association of dietary macronutrient composition and non-alcoholic fatty liver disease in an ageing population: the Rotterdam Study

(2018) Louise JM Alferink et al.   GUT

Can a ketogenic diet be safely used to improve glycaemic control in a child with type 1 diabetes?

(2018) Anne-Marie McClean et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Effect of diet protein restriction on progression of chronic kidney disease: A systematic review and meta-analysis

(2018) Bingjuan Yan et al.   PLoS One

The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease

(2018) Gina M. Broom et al.   NUTRITION

Association of whole grain intake with all-cause, cardiovascular, and cancer mortality: a systematic review and dose–response meta-analysis from prospective cohort studies

(2017) B Zhang et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies

(2017) Dagfinn Aune et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Treatment of NAFLD with diet, physical activity and exercise

(2017) Manuel Romero-Gómez et al.   JOURNAL OF HEPATOLOGY

An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial

(2017) Laura R Saslow et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Dietary Patterns and Type 2 Diabetes: A Systematic Literature Review and Meta-Analysis of Prospective Studies

(2017) Franziska Jannasch et al.   JOURNAL OF NUTRITION

Dietary Protein Sources and Risk for Incident Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study

(2017) Bernhard Haring et al.   JOURNAL OF RENAL NUTRITION

Nutritional Management of Chronic Kidney Disease

(2017) Kamyar Kalantar-Zadeh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dietary patterns are associated with type 2 diabetes mellitus among middle-aged adults in Zhejiang Province, China

(2017) Long Shu et al.   Nutrition Journal

Dietary Composition Independent of Weight Loss in the Management of Non-Alcoholic Fatty Liver Disease

(2017) Tannaz Eslamparast et al.   Nutrients

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies

(2017) Christophe Kosinski et al.   Nutrients

Practice Paper of the Academy of Nutrition and Dietetics: Classic and Modified Ketogenic Diets for Treatment of Epilepsy

(2017) Kelly Roehl et al.   Journal of the Academy of Nutrition and Dietetics

Detrimental Impact of Microbiota-Accessible Carbohydrate-Deprived Diet on Gut and Immune Homeostasis: An Overview

(2017) Claire Immediato Daïen et al.   Frontiers in Immunology

Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men

(2016) Kevin D Hall et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes

(2016) Preeti Kanikarla-Marie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice

(2016) Giulio Marchesini et al.   HEPATOLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease

(2016) William B. Grant   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Red Meat Intake and Risk of ESRD

(2016) Quan-Lan Jasmine Lew et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prevalence and incidence of epilepsy

(2016) Kirsten M. Fiest et al.   NEUROLOGY

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus

(2016) A Goday et al.   Nutrition & Diabetes

MIND diet associated with reduced incidence of Alzheimer's disease

(2015) Martha Clare Morris et al.   Alzheimers & Dementia

High Dietary Acid Load Predicts ESRD among Adults with CKD

(2015) T. Banerjee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Carcinogenicity of consumption of red and processed meat

(2015) Véronique Bouvard et al.   LANCET ONCOLOGY

Prepregnancy low-carbohydrate dietary pattern and risk of gestational diabetes mellitus: a prospective cohort study

(2014) Wei Bao et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adolescent meat intake and breast cancer risk

(2014) Maryam S. Farvid et al.   INTERNATIONAL JOURNAL OF CANCER

Animal Protein and the Risk of Kidney Stones: A Comparative Metabolic Study of Animal Protein Sources

(2014) Chad R. Tracy et al.   JOURNAL OF UROLOGY

Do ketogenic diets really suppress appetite? A systematic review and meta-analysis

(2014) A. A. Gibson et al.   Obesity Reviews

Dietary protein sources in early adulthood and breast cancer incidence: prospective cohort study

(2014) M. S. Farvid et al.   BMJ-British Medical Journal

Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials

(2013) Nassib Bezerra Bueno et al.   BRITISH JOURNAL OF NUTRITION

Association of Apolipoprotein B and Nuclear Magnetic Resonance Spectroscopy-Derived LDL Particle Number with Outcomes in 25 Clinical Studies: Assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices

(2013) T. G. Cole et al.   CLINICAL CHEMISTRY

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

(2013) L. E. Hebert et al.   NEUROLOGY

Low-Carbohydrate Diets and All-Cause Mortality: A Systematic Review and Meta-Analysis of Observational Studies

(2013) Hiroshi Noto et al.   PLoS One

Diet-Microbiota Interactions and Their Implications for Healthy Living

(2013) Ian Jeffery et al.   Nutrients

Health-Promoting Components of Fruits and Vegetables in the Diet

(2013) Rui Hai Liu   Advances in Nutrition

Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease

(2012) Rebecca C. Schugar et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

What Is the Role of Advanced Lipoprotein Analysis in Practice?

(2012) Jennifer G. Robinson   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes

(2012) Talib A. Hussain et al.   NUTRITION

Health Benefits of Fruits and Vegetables

(2012) Joanne L. Slavin et al.   Advances in Nutrition

Low-carbohydrate diet scores and risk of type 2 diabetes in men

(2011) Lawrence de Koning et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects

(2011) Sven Haufe et al.   HEPATOLOGY

Associations of Diet with Albuminuria and Kidney Function Decline

(2010) J. Lin et al.   Clinical Journal of the American Society of Nephrology

Dietary ketosis enhances memory in mild cognitive impairment

(2010) Robert Krikorian et al.   NEUROBIOLOGY OF AGING

Lipoprotein Particle Profiles by Nuclear Magnetic Resonance Compared With Standard Lipids and Apolipoproteins in Predicting Incident Cardiovascular Disease in Women

(2009) Samia Mora et al.   CIRCULATION

Dietary Fat and Carbohydrates Differentially Alter Insulin Sensitivity During Caloric Restriction

(2009) Erik Kirk et al.   GASTROENTEROLOGY

Empiric Use of Potassium Citrate Reduces Kidney-Stone Incidence With the Ketogenic Diet

(2009) M. A. McNally et al.   PEDIATRICS

The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus

(2008) Eric C Westman et al.   Nutrition & Metabolism

An Overview of the Ketogenic Diet for Pediatric Epilepsy

(2008) Beth A. Zupec-Kania et al.   NUTRITION IN CLINICAL PRACTICE