- Home
- Publications
- Publication Search
- Publication Details
Title
Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer
Authors
Keywords
-
Journal
Cellular and Molecular Gastroenterology and Hepatology
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-07-23
DOI
10.1016/j.jcmgh.2021.07.006
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis
- (2020) Yaqing Zhang et al. Cancer Discovery
- Tumor-derived prostaglandin E2 promotes p50 NF-κB-dependent differentiation of monocytic MDSC
- (2020) Chiara Porta et al. CANCER RESEARCH
- Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells’ heterogeneity
- (2020) Yehuda Schlesinger et al. Nature Communications
- Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer
- (2020) Sara A. Väyrynen et al. CLINICAL CANCER RESEARCH
- Hepatocytes direct the formation of a pro-metastatic niche in the liver
- (2019) Jae W. Lee et al. NATURE
- Immunotherapy of melanoma: facts and hopes
- (2019) Sarah A Weiss et al. CLINICAL CANCER RESEARCH
- Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes
- (2019) Deborah B Doroshow et al. CLINICAL CANCER RESEARCH
- Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
- (2019) Christopher J. Halbrook et al. Cell Metabolism
- The role of macrophages in the resolution of inflammation
- (2019) Satoshi Watanabe et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
- (2019) Marcus Noel et al. INVESTIGATIONAL NEW DRUGS
- Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies
- (2019) Roheena Z. Panni et al. Science Translational Medicine
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
- (2019) Ela Elyada et al. Cancer Discovery
- Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3
- (2019) Rosalinda Trovato et al. Journal for ImmunoTherapy of Cancer
- Genome-Wide Somatic Copy Number Alterations and Mutations in High-Grade Pancreatic Intraepithelial Neoplasia
- (2018) Tatsuo Hata et al. AMERICAN JOURNAL OF PATHOLOGY
- Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy
- (2018) Jinyang Li et al. IMMUNITY
- Myeloid-derived suppressor cells coming of age
- (2018) Filippo Veglia et al. NATURE IMMUNOLOGY
- CSF1R + Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype
- (2018) Juliana B. Candido et al. Cell Reports
- FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
- (2018) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting both tumour-associated CXCR2+neutrophils and CCR2+macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
- (2017) Timothy M Nywening et al. GUT
- Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
- (2017) Yu Zhu et al. IMMUNITY
- Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance
- (2017) Kristen B. Long et al. MOLECULAR IMMUNOLOGY
- Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
- (2017) Vinod P. Balachandran et al. NATURE
- Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
- (2017) Peter Storz Nature Reviews Gastroenterology & Hepatology
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
- (2017) Julienne L. Carstens et al. Nature Communications
- Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis
- (2017) Takahiro Tsujikawa et al. Cell Reports
- Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice
- (2017) Yaqing Zhang et al. eLife
- T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal Adenocarcinoma
- (2017) Ingunn M. Stromnes et al. Cancer Immunology Research
- CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma
- (2016) Colin W. Steele et al. CANCER CELL
- Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
- (2016) Yaqing Zhang et al. GUT
- Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer
- (2016) Heidi Griesmann et al. GUT
- Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
- (2016) Timothy M Nywening et al. LANCET ONCOLOGY
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
- (2016) Sebastian R. Nielsen et al. NATURE CELL BIOLOGY
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma
- (2016) T. Chao et al. Cancer Immunology Research
- Pancreatic cancer
- (2016) Jorg Kleeff et al. Nature Reviews Disease Primers
- Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
- (2015) S. Takeuchi et al. CANCER RESEARCH
- Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6Clow F4/80+ Extratumoral Macrophages
- (2015) Gregory L. Beatty et al. GASTROENTEROLOGY
- Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
- (2015) Douglas Marvel et al. JOURNAL OF CLINICAL INVESTIGATION
- nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancer: Long-Term Survival From a Phase III Trial
- (2015) D. Goldstein et al. JNCI-Journal of the National Cancer Institute
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- (2015) Bruno Costa-Silva et al. NATURE CELL BIOLOGY
- nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancer: Long-Term Survival From a Phase III Trial
- (2015) D. Goldstein et al. JNCI-Journal of the National Cancer Institute
- Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma
- (2015) R. Winograd et al. Cancer Immunology Research
- Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy
- (2014) Michelle N. Messmer et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models
- (2014) Y. Zhu et al. CANCER RESEARCH
- Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity
- (2014) Ingunn M Stromnes et al. GUT
- Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
- (2014) J.-I. Youn et al. JOURNAL OF IMMUNOLOGY
- Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy
- (2014) S. L. Highfill et al. Science Translational Medicine
- Mutant KRAS–Induced Expression of ICAM-1 in Pancreatic Acinar Cells Causes Attraction of Macrophages to Expedite the Formation of Precancerous Lesions
- (2014) Geou-Yarh Liou et al. Cancer Discovery
- Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
- (2014) Gregory L Beatty OncoImmunology
- NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription
- (2013) Susan J. Burke et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
- (2013) Y Ino et al. BRITISH JOURNAL OF CANCER
- CD40 immunotherapy for pancreatic cancer
- (2013) Robert H. Vonderheide et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis
- (2013) D. E. Sanford et al. CLINICAL CANCER RESEARCH
- MAPK Signaling Is Required for Dedifferentiation of Acinar Cells and Development of Pancreatic Intraepithelial Neoplasia in Mice
- (2013) Meredith A. Collins et al. GASTROENTEROLOGY
- Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
- (2013) Geou-Yarh Liou et al. JOURNAL OF CELL BIOLOGY
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
- (2013) Daniel D. Von Hoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
- (2012) Janel L. Kopp et al. CANCER CELL
- Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer
- (2012) Lauren J. Bayne et al. CANCER CELL
- Oncogenic Kras-Induced GM-CSF Production Promotes the Development of Pancreatic Neoplasia
- (2012) Yuliya Pylayeva-Gupta et al. CANCER CELL
- KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma
- (2012) Jianhua Ling et al. CANCER CELL
- EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis
- (2012) Christine M. Ardito et al. CANCER CELL
- Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth
- (2012) Matthew R. Porembka et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses
- (2012) J. B. Mitchem et al. CANCER RESEARCH
- EMT and Dissemination Precede Pancreatic Tumor Formation
- (2012) Andrew D. Rhim et al. CELL
- Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives
- (2012) Patrick Raber et al. IMMUNOLOGICAL INVESTIGATIONS
- Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
- (2012) Meredith A. Collins et al. JOURNAL OF CLINICAL INVESTIGATION
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas
- (2012) H J Maier et al. ONCOGENE
- Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma
- (2011) Hideaki Ijichi et al. JOURNAL OF CLINICAL INVESTIGATION
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
- (2011) G. L. Beatty et al. SCIENCE
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Small Molecule-Mediated Activation of the Integrin CD11b/CD18 Reduces Inflammatory Disease
- (2011) D. Maiguel et al. Science Signaling
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
- (2009) Hiroshi Kurahara et al. JOURNAL OF SURGICAL RESEARCH
- The IKK Complex, a Central Regulator of NF- B Activation
- (2009) A. Israel Cold Spring Harbor Perspectives in Biology
- Pancreatic Cancer
- (2008) Anirban Maitra et al. Annual Review of Pathology-Mechanisms of Disease
- Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
- (2008) Paulo C. Rodríguez et al. IMMUNOLOGICAL REVIEWS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started