Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

(2012) Jaroslaw Daniluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence

(2011) Carmen Guerra et al.   CANCER CELL

Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression

(2011) Akihisa Fukuda et al.   CANCER CELL

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

STAT3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis

(2011) R. B. Corcoran et al.   CANCER RESEARCH

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

(2011) Katerina Vlantis et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

(2011) Eleni Maniati et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network

(2011) Haoqiang Ying et al.   Cancer Discovery

NF-κB promotes epithelial–mesenchymal transition, migration and invasion of pancreatic carcinoma cells

(2010) Harald J. Maier et al.   CANCER LETTERS

Pancreatic Cancer

(2010) Manuel Hidalgo   NEW ENGLAND JOURNAL OF MEDICINE

Inflammation and pancreatic cancer: an evidence-based review

(2009) Julia B Greer et al.   CURRENT OPINION IN PHARMACOLOGY

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer

(2009) V. Fendrich et al.   GUT

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology