Imbalance of Systemic Redox Biomarkers in Children with Epilepsy: Role of Ferroptosis

Combination of serum and CSF neurofilament-light and neuroinflammatory biomarkers to evaluate ALS

(2021) Alexandre Brodovitch et al.   Scientific Reports

The Role of NADPH Oxidase in Neuronal Death and Neurogenesis after Acute Neurological Disorders

(2021) Song Hee Lee et al.   Antioxidants

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease

(2020) Lisa Mayr et al.   Nature Communications

Approaches for Reactive Oxygen Species and Oxidative Stress Quantification in Epilepsy

(2020) Rhoda Olowe et al.   Antioxidants

Antioxidants Targeting Mitochondrial Oxidative Stress: Promising Neuroprotectants for Epilepsy

(2020) Nan Yang et al.   Oxidative Medicine and Cellular Longevity

GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis

(2019) Giovanni C. Forcina et al.   PROTEOMICS

Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration: The role of vitamin E

(2019) Patrizia Ambrogini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activation of nicotinamide adenine dinucleotide phosphate oxidase is the primary trigger of epileptic seizures in rodent models

(2019) Anton Malkov et al.   ANNALS OF NEUROLOGY

Increased Serum S100B Levels in Patients With Epilepsy: A Systematic Review and Meta-Analysis Study

(2019) Kai-Ge Liang et al.   Frontiers in Neuroscience

Redox-Related Neuronal Death and Crosstalk as Drug Targets: Focus on Epilepsy

(2019) Xiao-Yuan Mao et al.   Frontiers in Neuroscience

Reactive oxygen species in status epilepticus

(2019) T. Shekh-Ahmad et al.   EPILEPSY & BEHAVIOR

Ferroptosis Induction in Pentylenetetrazole Kindling and Pilocarpine-Induced Epileptic Seizures in Mice

(2019) Xiao-Yuan Mao et al.   Frontiers in Neuroscience

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy

(2019) Tawfeeq Shekh-Ahmad et al.   Redox Biology

Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators

(2019) Kajarabille et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy

(2018) Tawfeeq Shekh-Ahmad et al.   BRAIN

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

Oxidative stress in status epilepticus: A clinical-radiological correlation

(2018) Jayantee Kalita et al.   BRAIN RESEARCH

Synergistic protection against acute flurothyl-induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone

(2017) Timothy A. Simeone et al.   EPILEPSIA

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology

(2017) Ingrid E. Scheffer et al.   EPILEPSIA

WONOEP appraisal: Molecular and cellular biomarkers for epilepsy

(2016) Lauren E. Walker et al.   EPILEPSIA

NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy

(2015) A. Pecorelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Antioxidants as a Preventive Treatment for Epileptic Process: A Review of the Current Status

(2015) Bostjan Martinc et al.   Current Neuropharmacology

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

(2015) Liuji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Flavonoids on Oxidative Stress in Epilepsy

(2015) Tâmara Coimbra Diniz et al.   Oxidative Medicine and Cellular Longevity

Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia

(2014) Amanda C Smith et al.   JOURNAL OF MEDICAL GENETICS

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Baicalein ameliorates cognitive deficits in epilepsy-like tremor rat

(2014) Xiaoyuan Mao et al.   NEUROLOGICAL SCIENCES

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Biomarkers of lipid peroxidation in clinical material

(2013) Etsuo Niki   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Post-treatment of an NADPH oxidase inhibitor prevents seizure-induced neuronal death

(2013) Jin Hee Kim et al.   BRAIN RESEARCH

Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure

(2013) Wei Wang et al.   BRAIN RESEARCH

Modulation of Antioxidant Enzymatic Activities by Certain Antiepileptic Drugs (Valproic Acid, Oxcarbazepine, and Topiramate): Evidence in Humans and Experimental Models

(2013) Noemí Cárdenas-Rodríguez et al.   Oxidative Medicine and Cellular Longevity

Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal

(2012) Ying Huang et al.   Cell and Bioscience

Interactions of glutathione transferases with 4-hydroxynonenal

(2011) Larissa M. Balogh et al.   DRUG METABOLISM REVIEWS

Role of oxidative stress in epileptic seizures

(2011) Eun-Joo Shin et al.   NEUROCHEMISTRY INTERNATIONAL

Lipid peroxidation of poly-unsaturated fatty acids in normal and obese adipose tissues

(2011) G. Cohen et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Anticonvulsant potential of the peroxisome proliferator-activated receptor gamma agonist pioglitazone in pentylenetetrazole-induced acute seizures and kindling in mice

(2010) Dalaal M. Abdallah   BRAIN RESEARCH

Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy

(2010) Rafaela R.F. Pestana et al.   NEUROSCIENCE LETTERS

Oxidative Stress in The Hippocampus During Experimental Seizures Can Be Ameliorated With The Antioxidant Ascorbic Acid

(2010) Ítala Mônica Sales Santos et al.   Oxidative Medicine and Cellular Longevity

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

(2009) Patrick Kwan et al.   EPILEPSIA

Effects of epilepsy and valproic acid on oxidant status in children with idiopathic epilepsy

(2009) Uluç Yiş et al.   EPILEPSY RESEARCH

Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients

(2008) Wei Shang et al.   BMC NEUROSCIENCE