Dynamic Changes of the Bone Marrow Niche: Mesenchymal Stromal Cells and Their Progeny During Aging and Leukemia

Integrated decoding hematopoiesis and leukemogenesis using single-cell sequencing and its medical implication

(2021) Pengfei Qin et al.   Cell Discovery

Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging

(2021) Peng Deng et al.   Cell Stem Cell

Symmetric and asymmetric activation of hematopoietic stem cells

(2021) Dirk Loeffler et al.   CURRENT OPINION IN HEMATOLOGY

Remodeling of Bone Marrow Niches and Roles of Exosomes in Leukemia

(2021) Takanori Yamaguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity

(2021) Igor Dolgalev et al.   Frontiers in Cell and Developmental Biology

CircRNA hsa_circ_0006215 promotes osteogenic differentiation of BMSCs and enhances osteogenesis–angiogenesis coupling by competitively binding to miR-942-5p and regulating RUNX2 and VEGF

(2021) Houlin Ji et al.   Aging-US

Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course

(2021) Giulia Borella et al.   BLOOD

Identification of CXCL12‐abundant reticular cells in human adult bone marrow

(2021) Kazunari Aoki et al.   BRITISH JOURNAL OF HAEMATOLOGY

Translational Animal Models Provide Insight Into Mesenchymal Stromal Cell (MSC) Secretome Therapy

(2021) Rebecca M. Harman et al.   Frontiers in Cell and Developmental Biology

Non-Coding RNAs Steering the Senescence-Related Progress, Properties, and Application of Mesenchymal Stem Cells

(2021) Jingyi Cai et al.   Frontiers in Cell and Developmental Biology

The elevated level of IL-1α in the bone marrow of aged mice leads to MSC senescence partly by down-regulating Bmi-1

(2021) Xueling Zheng et al.   EXPERIMENTAL GERONTOLOGY

Human, mouse, and dog bone marrow show similar mesenchymal stromal cells within a distinctive microenvironment

(2021) Berenice Meza-León et al.   EXPERIMENTAL HEMATOLOGY

A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia

(2020) Prithviraj Bose et al.   LEUKEMIA

Editorial: Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies

(2020) Guido Moll et al.   Frontiers in Immunology

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy

(2020) Abdelkrim Hmadcha et al.   Frontiers in Bioengineering and Biotechnology

Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway

(2020) Mahmoud Al-Azab et al.   Aging-US

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

(2020) Leilei Zhong et al.   eLife

Celastrol regulates bone marrow mesenchymal stem cell fate and bone-fat balance in osteoporosis and skeletal aging by inducing PGC-1α signaling

(2020) Li Li et al.   Aging-US

Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

(2020) Luis A. Costa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipocalin-2 counteracts metabolic dysregulation in obesity and diabetes

(2020) Ioanna Mosialou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

(2020) Xiaomo Wu et al.   Stem Cell Research & Therapy

Human Aging Alters the Spatial Organization between CD34+ Hematopoietic Cells and Adipocytes in Bone Marrow

(2020) Alicia G. Aguilar-Navarro et al.   Stem Cell Reports

Shattering barriers toward clinically meaningful MSC therapies

(2020) Oren Levy et al.   Science Advances

microRNA‐146a controls age‐related bone loss

(2020) Victoria Saferding et al.   AGING CELL

Unraveling Hematopoiesis through the Lens of Genomics

(2020) L. Alexander Liggett et al.   CELL

Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing

(2020) Simona Valletta et al.   Nature Communications

Senescent mesenchymal stem/stromal cells and restoring their cellular functions

(2020) Qing-Shu Meng et al.   World Journal of Stem Cells

Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence

(2020) Ha-Neui Kim et al.   JCI Insight

Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

(2020) Nils B. Leimkühler et al.   Cell Stem Cell

Microfluidics and organ-on-a-chip technologies: A systematic review of the methods used to mimic bone marrow

(2020) Gabriel Santos Rosalem et al.   PLoS One

Sirt3 Attenuates Oxidative Stress Damage and Rescues Cellular Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Superoxide Dismutase 2

(2020) Cao Ma et al.   Frontiers in Cell and Developmental Biology

Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing

(2020) Patrick S. Stumpf et al.   Communications Biology

Mobilization of leukemic cells using plerixafor as part of a myeloablative preparative regimen for patients with AML undergoing allografting: assessment of safety and tolerability

(2019) Fotios V. Michelis et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome

(2019) Flavia Ribezzo et al.   LEUKEMIA

Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells

(2019) Eliane Antonioli et al.   PLoS One

Haematopoietic stem cell activity and interactions with the niche

(2019) Sandra Pinho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mesenchymal stem cells in suppression or progression of hematologic malignancy: current status and challenges

(2019) Myoung Woo Lee et al.   LEUKEMIA

Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture

(2019) Shutong Liu et al.   Journal of Translational Medicine

Single-Cell Profiles and Clinically Useful Properties of Human Mesenchymal Stem Cells of Adipose and Bone Marrow Origin

(2019) Wenyan Zhou et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

(2019) Ninib Baryawno et al.   CELL

The bone marrow microenvironment at single-cell resolution

(2019) Anastasia N. Tikhonova et al.   NATURE

Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells

(2019) Fumio Nakahara et al.   NATURE CELL BIOLOGY

FGF21 Mediates Mesenchymal Stem Cell Senescence via Regulation of Mitochondrial Dynamics

(2019) Xin Li et al.   Oxidative Medicine and Cellular Longevity

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

(2019) Ya-Hsuan Ho et al.   Cell Stem Cell

Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation

(2019) Laetitia Boutin et al.   HAEMATOLOGICA

Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths

(2019) Samuel L. Wolock et al.   Cell Reports

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche

(2019) Yuko Kato et al.   EXPERIMENTAL HEMATOLOGY

Chemokines in Physiological and Pathological Bone Remodeling

(2019) Laura J. Brylka et al.   Frontiers in Immunology

A Revised Perspective of Skeletal Stem Cell Biology

(2019) Thomas H. Ambrosi et al.   Frontiers in Cell and Developmental Biology

Clonal hematopoiesis as a model for premalignant changes during aging

(2019) David P. Steensma et al.   EXPERIMENTAL HEMATOLOGY

Mapping and targeting of the leukemic microenvironment

(2019) Matthew T. Witkowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization

(2019) Chiara Baccin et al.   NATURE CELL BIOLOGY

Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

(2019) Patrick M. Helbling et al.   Cell Reports

A phase I–II study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia

(2018) David Martínez-Cuadrón et al.   ANNALS OF HEMATOLOGY

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

(2018) Delfim Duarte et al.   Cell Stem Cell

Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia

(2018) Gail J Roboz et al.   HAEMATOLOGICA

Dexamethasone in hyperleukocytic acute myeloid leukemia

(2018) Sarah Bertoli et al.   HAEMATOLOGICA

Niches for Hematopoietic Stem Cells and Their Progeny

(2018) Qiaozhi Wei et al.   IMMUNITY

Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation

(2018) Thomas Vogl et al.   JOURNAL OF CLINICAL INVESTIGATION

Associations of myeloid hematological diseases of the elderly with osteoporosis: A longitudinal analysis of routine health care data

(2018) Thomas Datzmann et al.   LEUKEMIA RESEARCH

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

(2018) Maria Maryanovich et al.   NATURE MEDICINE

Bone loss and hematological malignancies in adults: a pilot study

(2018) Rosa Ruchlemer et al.   SUPPORTIVE CARE IN CANCER

The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussion

(2018) Tiziano Barbui et al.   Blood Cancer Journal

Regulation of Bone Remodeling by Parathyroid Hormone

(2018) Marc N. Wein et al.   Cold Spring Harbor Perspectives in Medicine

Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia

(2018) Gail J Roboz et al.   HAEMATOLOGICA

Dexamethasone in hyperleukocytic acute myeloid leukemia

(2018) Sarah Bertoli et al.   HAEMATOLOGICA

Application of Mesenchymal Stem Cells for Therapeutic Agent Delivery in Anti-tumor Treatment

(2018) Daria S. Chulpanova et al.   Frontiers in Pharmacology

Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging

(2018) Chang-Jun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Wharton's Jelly Mesenchymal Stem Cells Show Unique Gene Expression Compared with Bone Marrow Mesenchymal Stem Cells Using Single-Cell RNA-Sequencing

(2018) Angela N. Barrett et al.   STEM CELLS AND DEVELOPMENT

Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice

(2017) Linh Ho et al.   ENDOCRINOLOGY

Bone–Fat Interaction

(2017) Elizabeth Rendina-Ruedy et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool

(2017) Rialnat A Lawal et al.   JOURNAL OF BONE AND MINERAL RESEARCH

LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment

(2017) Delfina Costa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Versatile humanized niche model enables study of normal and malignant human hematopoiesis

(2017) Ander Abarrategi et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion

(2017) B Kumar et al.   LEUKEMIA

DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia

(2017) Hakan Ozdogan et al.   LEUKEMIA RESEARCH

HSC Niche Biology and HSC Expansion Ex Vivo

(2017) Sachin Kumar et al.   TRENDS IN MOLECULAR MEDICINE

Parathyroid hormone 1-34 and skeletal anabolic action

(2017) L. Osagie-Clouard et al.   Bone & Joint Research

Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Sirt1

(2017) Cao Ma et al.   PLoS One

Human Primary Bone Marrow Mesenchymal Stromal Cells and Their in vitro Progenies Display Distinct Transcriptional Profile Signatures

(2017) Roshanak Ghazanfari et al.   Scientific Reports

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

(2016) Q Chen et al.   CELL DEATH AND DIFFERENTIATION

Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia

(2016) Noemi A. Zambetti et al.   Cell Stem Cell

Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-κB activity

(2016) Tzu-hua Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Extended time-lapse in vivo imaging of tibia bone marrow to visualize dynamic hematopoietic stem cell engraftment

(2016) S Kim et al.   LEUKEMIA

Exosomes derived from human mesenchymal stem cells promote gastric cancer cell growth and migration via the activation of the Akt pathway

(2016) Hongbing Gu et al.   Molecular Medicine Reports

Distinct bone marrow blood vessels differentially regulate haematopoiesis

(2016) Tomer Itkin et al.   NATURE

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment

(2016) Lei Dong et al.   NATURE

Enhanced Hematopoietic Stem Cell Self-Renewal-Promoting Ability of Clonal Primary Mesenchymal Stromal/Stem cells Versus Their Osteogenic Progeny

(2016) Qiling He et al.   STEM CELLS

Marrow Adipose Tissue: Trimming the Fat

(2016) Erica L. Scheller et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow

(2016) Vionnie W.C. Yu et al.   Stem Cell Reports

Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia

(2015) Jin-A Kim et al.   CANCER RESEARCH

Skeletal stem cells

(2015) P. Bianco et al.   DEVELOPMENT

Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia

(2015) S Geyh et al.   LEUKEMIA

Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells

(2015) Wenzheng Xia et al.   Stem Cell Research & Therapy

Leukemia Propagating Cells Rebuild an Evolving Niche in Response to Therapy

(2014) Cai-Wen Duan et al.   CANCER CELL

Leptin Receptor Makes Its Mark on MSCs

(2014) Yumi Matsuzaki et al.   Cell Stem Cell

Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche

(2014) Maher Hanoun et al.   Cell Stem Cell

Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit

(2014) Hind Medyouf et al.   Cell Stem Cell

Lipocalin 2 decreases senescence of bone marrow-derived mesenchymal stem cells under sub-lethal doses of oxidative stress

(2014) Bahareh Bahmani et al.   CELL STRESS & CHAPERONES

Lipocalin 2 Regulates Brown Fat Activation via a Nonadrenergic Activation Mechanism

(2014) Yuanyuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms

(2014) Lorena Arranz et al.   NATURE

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

(2014) Aruna Kode et al.   NATURE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

SMAD Signaling Regulates CXCL12 Expression in the Bone Marrow Niche, Affecting Homing and Mobilization of Hematopoietic Progenitors

(2014) Satish Khurana et al.   STEM CELLS

Parathyroid Hormone Enhances Hematopoietic Expansion Via Upregulation of Cadherin-11 in Bone Marrow Mesenchymal Stromal Cells

(2014) Hisayuki Yao et al.   STEM CELLS

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

(2013) Georg Siegel et al.   BMC Medicine

Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs

(2013) Borhane Guezguez et al.   Cell Stem Cell

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

(2013) Koen Schepers et al.   Cell Stem Cell

Lipocalin-2-mediated upregulation of various antioxidants and growth factors protects bone marrow-derived mesenchymal stem cells against unfavorable microenvironments

(2013) Raheleh Halabian et al.   CELL STRESS & CHAPERONES

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

(2013) Fabienne Brenet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PDGFRα and CD51 mark human Nestin+sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

(2013) Sandra Pinho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells

(2013) S Geyh et al.   LEUKEMIA

Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model

(2013) Ruizhu Lin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Differential stem- and progenitor-cell trafficking by prostaglandin E2

(2013) Jonathan Hoggatt et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Lipocalin-2 increases fat oxidation in vitro and is correlated with energy expenditure in normal weight but not obese women

(2013) Chad M. Paton et al.   Obesity

IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation

(2013) Anna Caselli et al.   STEM CELLS

PTH expands short-term murine hemopoietic stem cells through T cells

(2012) J.-Y. Li et al.   BLOOD

Myelopoiesis is regulated by osteocytes through Gs -dependent signaling

(2012) K. Fulzele et al.   BLOOD

Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells

(2012) L. M. Calvi et al.   BLOOD

BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies

(2012) M. R. Kuhne et al.   CLINICAL CANCER RESEARCH

Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients

(2012) C. Santamaria et al.   HAEMATOLOGICA

Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling

(2012) Bing Yu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Differential Regulation of CXCL5 by FGF2 in Osteoblastic and Endothelial Niche Cells Supports Hematopoietic Stem Cell Migration

(2012) Kyung-Ae Yoon et al.   STEM CELLS AND DEVELOPMENT

Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells

(2012) Andre F Steinert et al.   ARTHRITIS RESEARCH & THERAPY

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model

(2012) Y Zhang et al.   Cell Death & Disease

p38 MAPK Contributes to the Growth Inhibition of Leukemic Tumor Cells Mediated by Human Umbilical Cord Mesenchymal Stem Cells

(2011) Kun Tian et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lipocalin-2 Deficiency Impairs Thermogenesis and Potentiates Diet-Induced Insulin Resistance in Mice

(2010) H. Guo et al.   DIABETES

Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells

(2010) Jennifer R Stevens et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

BMP4 regulates the hematopoietic stem cell niche

(2009) D. C. Goldman et al.   BLOOD

Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation

(2009) J. Hoggatt et al.   BLOOD

In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells

(2009) B. J. Frisch et al.   BLOOD

Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis

(2009) Wen-ting Xu et al.   CANCER LETTERS

Human bone marrow mesenchymal cells express NG2: possible increase in discriminative ability of flow cytometry during mesenchymal stromal cell identification

(2009) Ilknur Kozanoglu et al.   CYTOTHERAPY

Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

(2009) Satoru Morikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a bone marrow-derived mesenchymal progenitor cell subset that can contribute to the gastric epithelium

(2009) Tomoyuki Okumura et al.   LABORATORY INVESTIGATION

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Effects of human bone marrow stromal cell line (HFCL) on the proliferation, differentiation and apoptosis of acute myeloid leukemia cell lines U937, HL-60 and HL-60/VCR

(2008) Rong Liang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Osteoblastic regulation of B lymphopoiesis is mediated by Gs -dependent signaling pathways

(2008) J. Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic Stem Cells Regulate Mesenchymal Stromal Cell Induction into Osteoblasts Thereby Participating in the Formation of the Stem Cell Niche

(2008) Younghun Jung et al.   STEM CELLS

Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells

(2007) Kenichi Miharada et al.   JOURNAL OF CELLULAR PHYSIOLOGY