Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
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Title
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-08-14
DOI
10.1038/s41467-020-17942-7
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Note: Only part of the references are listed.- Aged murine hematopoietic stem cells drive aging-associated immune remodeling
- (2018) Hanna Leins et al. BLOOD
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- (2017) Y Mei et al. LEUKEMIA
- MultiQC: summarize analysis results for multiple tools and samples in a single report
- (2016) Philip Ewels et al. BIOINFORMATICS
- Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions
- (2016) Jeffrey M. Bernitz et al. CELL
- Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing
- (2016) Roy Drissen et al. NATURE IMMUNOLOGY
- Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
- (2016) Amit Grover et al. Nature Communications
- Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias
- (2016) Alexandra Rundberg Nilsson et al. PLoS One
- Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors
- (2015) Curtis J. Henry et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2015) Melania Tesio et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Single-gene negative binomial regression models for RNA-Seq data with higher-order asymptotic inference
- (2015) Yanming Di Statistics and Its Interface
- Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal
- (2014) Deqiang Sun et al. Cell Stem Cell
- Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis
- (2014) Nina Cabezas-Wallscheid et al. Cell Stem Cell
- Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate
- (2014) Amit Grover et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells
- (2014) Meng Zhao et al. NATURE MEDICINE
- An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia
- (2014) Michael Dussiot et al. NATURE MEDICINE
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing
- (2013) Maria Carolina Florian et al. NATURE
- Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
- (2013) Alejandra Sanjuan-Pla et al. NATURE
- Smart-seq2 for sensitive full-length transcriptome profiling in single cells
- (2013) Simone Picelli et al. NATURE METHODS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
- (2012) A. V. Ergen et al. BLOOD
- Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs
- (2012) Claudia Benz et al. Cell Stem Cell
- B cell maintenance and function in aging
- (2012) Igor Kogut et al. SEMINARS IN IMMUNOLOGY
- FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
- (2011) Elena Mancini et al. EMBO JOURNAL
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- (2011) Brad Dykstra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells
- (2010) Y. Nakamura et al. BLOOD
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Relationship between anaemia and cognitive functions in elderly people
- (2009) Hakan M. Terekeci et al. European Journal of Internal Medicine
- Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow
- (2009) Satoru Morikawa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of the TGF- receptor I kinase promotes hematopoiesis in MDS
- (2008) L. Zhou et al. BLOOD
- A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
- (2008) R. H. Cho et al. BLOOD
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
- (2008) Anne Wilson et al. CELL
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