Premyelinating Oligodendrocytes: Mechanisms Underlying Cell Survival and Integration

Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor

(2021) Amin Sherafat et al.   Nature Communications

Prolonged Environmental Enrichment Promotes Developmental Myelination

(2021) Evan Z. Goldstein et al.   Frontiers in Cell and Developmental Biology

The mechanistic target of rapamycin pathway downregulates bone morphogenetic protein signaling to promote oligodendrocyte differentiation

(2020) Isis M. Ornelas et al.   GLIA

Preservation of a remote fear memory requires new myelin formation

(2020) Simon Pan et al.   NATURE NEUROSCIENCE

Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory

(2020) Fei Wang et al.   NATURE NEUROSCIENCE

Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery

(2020) Thomas A. Forbes et al.   Nature Communications

Astrocyte Support for Oligodendrocyte Differentiation can be Conveyed via Extracellular Vesicles but Diminishes with Age

(2020) Cory M. Willis et al.   Scientific Reports

Motor learning promotes remyelination via new and surviving oligodendrocytes

(2020) Clara M. Bacmeister et al.   NATURE NEUROSCIENCE

Neuron-oligodendroglia interactions: Activity-dependent regulation of cellular signaling

(2020) Michael A. Thornton et al.   NEUROSCIENCE LETTERS

Microglia phagocytose myelin sheaths to modify developmental myelination

(2020) Alexandria N. Hughes et al.   NATURE NEUROSCIENCE

Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis

(2020) Karl E. Carlström et al.   Nature Communications

Fractalkine-Dependent Microglial Pruning of Viable Oligodendrocyte Progenitor Cells Regulates Myelination

(2020) Ashley D. Nemes-Baran et al.   Cell Reports

Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury

(2020) Elisa M. Floriddia et al.   Nature Communications

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Dynamics of oligodendrocyte generation in multiple sclerosis

(2019) Maggie S. Y. Yeung et al.   NATURE

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment

(2019) Anna C. Geraghty et al.   NEURON

Myelin in the Central Nervous System: Structure, Function, and Pathology

(2019) Christine Stadelmann et al.   PHYSIOLOGICAL REVIEWS

Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

(2019) Björn Neumann et al.   Cell Stem Cell

Oligodendrocytes express synaptic proteins that modulate myelin sheath formation

(2019) Alexandria N. Hughes et al.   Nature Communications

Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS

(2019) Minou Djannatian et al.   Nature Communications

Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS

(2019) Anna Klingseisen et al.   DEVELOPMENTAL CELL

The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function

(2018) Oladapo E. Olaniru et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Catalpol Inhibits Ischemia-Induced Premyelinating Oligodendrocyte Damage through Regulation of Intercellular Calcium Homeostasis via Na+/Ca2+ Exchanger 3

(2018) Qiyan Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activity-Dependent Myelination of Parvalbumin Interneurons Mediated by Axonal Morphological Plasticity

(2018) Jeffrey Stedehouder et al.   JOURNAL OF NEUROSCIENCE

Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex

(2018) Ethan G. Hughes et al.   NATURE NEUROSCIENCE

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner

(2018) Stanislaw Mitew et al.   Nature Communications

Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells

(2018) Stefanie Giera et al.   eLife

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development

(2018) Sueli Marques et al.   DEVELOPMENTAL CELL

Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis

(2018) Lu O. Sun et al.   CELL

Axoglial Adhesion by Cadm4 Regulates CNS Myelination

(2018) Nimrod Elazar et al.   NEURON

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial

(2017) Ari J Green et al.   LANCET

Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation

(2017) Brittney A Beyer et al.   Nature Chemical Biology

Ca2+ activity signatures of myelin sheath formation and growth in vivo

(2017) Marion Baraban et al.   NATURE NEUROSCIENCE

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

(2017) Maryam K. Fard et al.   Science Translational Medicine

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

(2017) Qinjie Weng et al.   Scientific Reports

Remarkable Stability of Myelinating Oligodendrocytes in Mice

(2017) Richa B. Tripathi et al.   Cell Reports

Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation

(2017) Kazuya Kuboyama et al.   PLoS One

Progressive multiple sclerosis: from pathogenic mechanisms to treatment

(2016) Jorge Correale et al.   BRAIN

Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study

(2016) Caryl J. Schwartzbach et al.   JOURNAL OF NEUROLOGY

Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination

(2016) Z. Ou et al.   JOURNAL OF NEUROSCIENCE

Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

(2016) Lin Xiao et al.   NATURE NEUROSCIENCE

Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

(2016) Stephanie A. Redmond et al.   NEURON

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes

(2016) Minqing Jiang et al.   Nature Communications

An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

(2016) Michael B. Keough et al.   Nature Communications

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

(2016) Hyun-Jeong Yang et al.   Nature Communications

Control of adult neurogenesis by programmed cell death in the mammalian brain

(2016) Jae Ryun Ryu et al.   Molecular Brain

Pathological differences between white and grey matter multiple sclerosis lesions

(2015) Marloes Prins et al.   Annals of the New York Academy of Sciences

Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor

(2015) N. Miyamoto et al.   JOURNAL OF NEUROSCIENCE

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo

(2015) Sigrid Mensch et al.   NATURE NEUROSCIENCE

Neuronal activity biases axon selection for myelination in vivo

(2015) Jacob H Hines et al.   NATURE NEUROSCIENCE

Oligodendrocyte Development and Plasticity

(2015) Dwight E. Bergles et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

(2015) Ben Emery et al.   Cold Spring Harbor Perspectives in Biology

Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis

(2015) Juan Zhang et al.   Biomed Research International

Temporal oligodendrocyte lineage progression: In vitro models of proliferation, differentiation and myelination

(2014) Andreia Barateiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis

(2014) Tracy J. Yuen et al.   CELL

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

(2014) Maggie S.Y. Yeung et al.   CELL

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

(2014) Robert A Hill et al.   NATURE NEUROSCIENCE

Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

(2014) E. M. Gibson et al.   SCIENCE

High-Frequency Stimulation Induces Gradual Immediate Early Gene Expression in Maturing Adult-Generated Hippocampal Granule Cells

(2013) Tassilo Jungenitz et al.   CEREBRAL CORTEX

Inhibitors of myelination: ECM changes, CSPGs and PTPs

(2013) Danielle E. Harlow et al.   EXPERIMENTAL NEUROLOGY

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Same players, different game: AMPA receptor regulation in oligodendrocyte progenitors

(2011) Lindsay M De Biase et al.   NATURE NEUROSCIENCE

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

The Fate of Synaptic Input to NG2 Glial Cells: Neurons Specifically Downregulate Transmitter Release onto Differentiating Oligodendroglial Cells

(2010) M. Kukley et al.   JOURNAL OF NEUROSCIENCE

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

The Extracellular Matrix Molecule Hyaluronic Acid Regulates Hippocampal Synaptic Plasticity by Modulating Postsynaptic L-Type Ca2+ Channels

(2010) Gaga Kochlamazashvili et al.   NEURON

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

(2010) J. A. Sloane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice

(2010) Klaus Fabel   Frontiers in Neuroscience

Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK

(2009) Kumi Kawai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination

(2009) Ying Chen et al.   NATURE NEUROSCIENCE

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE