Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation

Systems biology guided by XCMS Online metabolomics

(2017) Tao Huan et al.   NATURE METHODS

α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells

(2016) Tara TeSlaa et al.   Cell Metabolism

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination

(2016) Feng Mei et al.   JOURNAL OF NEUROSCIENCE

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study

(2016) Ayman Tourbah et al.   Multiple Sclerosis Journal

Oligodendrocyte regeneration: Its significance in myelin replacement and neuroprotection in multiple sclerosis

(2016) Kelly A. Chamberlain et al.   NEUROPHARMACOLOGY

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study

(2016) Ayman Tourbah et al.   Multiple Sclerosis Journal

Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes

(2015) Halina Jurkowska et al.   AMINO ACIDS

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

A new mechanism of nervous system plasticity: activity-dependent myelination

(2015) R. Douglas Fields   NATURE REVIEWS NEUROSCIENCE

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse

(2014) Gerardo Ramos-Mandujano et al.   Stem Cell Research

Potential of Urinary Metabolites for Diagnosing Multiple Sclerosis

(2013) Teklab Gebregiworgis et al.   ACS Chemical Biology

Stem cell metabolism in tissue development and aging

(2013) N. Shyh-Chang et al.   DEVELOPMENT

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Neuron-oligodendrocyte myelination co-culture derived from embryonic rat spinal cord and cerebral cortex

(2013) Yi Pang et al.   Brain and Behavior

XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data

(2012) Ralf Tautenhahn et al.   ANALYTICAL CHEMISTRY

Taurine Induces Proliferation of Neural Stem Cells and Synapse Development in the Developing Mouse Brain

(2012) Mattu Chetana Shivaraj et al.   PLoS One

Induced Pluripotent Stem Cells Show Metabolomic Differences to Embryonic Stem Cells in Polyunsaturated Phosphatidylcholines and Primary Metabolism

(2012) John K. Meissen et al.   PLoS One

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

(2011) Athanasia D Panopoulos et al.   CELL RESEARCH

Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

(2011) Marek J. Noga et al.   Metabolomics

Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells

(2011) Jeffrey K. Huang et al.   Neurotherapeutics

Metabolic oxidation regulates embryonic stem cell differentiation

(2010) Oscar Yanes et al.   Nature Chemical Biology

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

(2010) Clare E. Buckley et al.   NEUROPHARMACOLOGY

Oxidative stress disrupts oligodendrocyte maturation

(2009) Heather Morein French et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Oligodendrocyte Development and Myelin Biogenesis: Parsing Out the Roles of Glycosphingolipids

(2009) Nicole Jackman et al.   PHYSIOLOGY

From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases

(2008) M. Dubois-Dalcq et al.   BRAIN

Myelin repair strategies: a cellular view

(2008) Vittorio Gallo et al.   CURRENT OPINION IN NEUROLOGY

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE