An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury

(2014) Bradley T. Lang et al.   NATURE

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Screening for Inhibitors of Microglia to Reduce Neuroinflammation

(2013) Shazia Samanani et al.   CNS & Neurological Disorders-Drug Targets

Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix

(2013) Rowena C. Cua et al.   GLIA

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Pathophysiology of the brain extracellular matrix: a new target for remyelination

(2013) Lorraine W. Lau et al.   NATURE REVIEWS NEUROSCIENCE

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Protocol to Isolate a Large Amount of Functional Oligodendrocyte Precursor Cells from the Cerebral Cortex of Adult Mice and Humans

(2013) Eva María Medina-Rodríguez et al.   PLoS One

Combination treatment with chondroitinase ABC in spinal cord injury—breaking the barrier

(2013) Rong-Rong Zhao et al.   Neuroscience Bulletin

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

Alterations in sulfated chondroitin glycosaminoglycans following controlled cortical impact injury in mice

(2012) Jae-Hyuk Yi et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Remyelination Therapy for Multiple Sclerosis

(2012) Michael B. Keough et al.   Neurotherapeutics

Enhancing remyelination in disease--can we wrap it up?

(2011) M. R. Kotter et al.   BRAIN

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire ofN- andO-Glycans without Direct Incorporation

(2011) Steven R. Barthel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis

(2011) Ani Grigorian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes

(2011) Justin R. Siebert et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of CNS Remyelination by the Presence of Semaphorin 3A

(2011) Y. A. Syed et al.   JOURNAL OF NEUROSCIENCE

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

(2010) J. A. Sloane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Regulation of Heparan Sulfate and Chondroitin Sulfate Glycosaminoglycan Biosynthesis by 4-Fluoro-glucosamine in Murine Airway Smooth Muscle Cells

(2009) Julie Nigro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Remyelination protects axons from demyelination-associated axon degeneration

(2008) K. A. Irvine et al.   BRAIN

Localization of chondroitin sulfate proteoglycan versican in adult brain with special reference to large projection neurons

(2008) Noriko Horii-Hayashi et al.   CELL AND TISSUE RESEARCH

Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3

(2007) James M. Massey et al.   EXPERIMENTAL NEUROLOGY