Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study

MTR recovery in brain lesions in the BECOME study of glatiramer acetate vs interferon β-1b

(2016) Robert A. Brown et al.   NEUROLOGY

In vivoquantitative magnetization transfer imaging correlates with histology during de- and remyelination in cuprizone-treated mice

(2015) Laura Turati et al.   NMR IN BIOMEDICINE

A Phase II study of a histamine H3 receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy

(2015) L. Fredrik Jarskog et al.   SCHIZOPHRENIA RESEARCH

A Randomized, Double-Blind, Placebo-Controlled, 16-Week Study of the H3 Receptor Antagonist, GSK239512 as a Monotherapy in Subjects with Mild-to-Moderate Alzheimer’s Disease

(2014) Richard Grove et al.   Current Alzheimer Research

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Imaging of repeated episodes of demyelination and remyelination in multiple sclerosis

(2014) Robert A. Brown et al.   NeuroImage-Clinical

Unexpectedly high affinity of a novel histamine H3receptor antagonist, GSK239512,in vivoin human brain, determined using PET

(2013) S Ashworth et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer’s Disease: A Preliminary Investigation

(2013) Pradeep J. Nathan et al.   Current Alzheimer Research

World Medical Association Declaration of Helsinki

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Segmentation of magnetization transfer ratio lesions for longitudinal analysis of demyelination and remyelination in multiple sclerosis

(2012) Robert A. Brown et al.   NEUROIMAGE

Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions

(2011) María I. Gaitán et al.   ANNALS OF NEUROLOGY

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Improving Test–Retest Variability of Visual-Evoked Responses in Multiple Sclerosis

(2010) Eva Thomae et al.   JOURNAL OF CLINICAL NEUROPHYSIOLOGY

Lesional magnetization transfer ratio: a feasible outcome for remyelinating treatment trials in multiple sclerosis

(2010) IJ van den Elskamp et al.   Multiple Sclerosis Journal

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis

(2010) Ranjan Dutta et al.   PROGRESS IN NEUROBIOLOGY

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Quantitative magnetic resonance of postmortem multiple sclerosis brain before and after fixation

(2008) Klaus Schmierer et al.   MAGNETIC RESONANCE IN MEDICINE

Outcome measures for trials of remyelinating agents in multiple sclerosis: retrospective longitudinal analysis of visual evoked potential latency

(2008) A Niklas et al.   Multiple Sclerosis Journal