Current Understandings of Core Pathways for the Activation of Mammalian Primordial Follicles

Validation study of the Access AMH antimüllerian hormone assay for the prediction of poor ovarian response to controlled ovarian stimulation

(2021) Valerie L. Baker et al.   FERTILITY AND STERILITY

In Vitro Activation Early Follicles: From the Basic Science to the Clinical Perspectives

(2021) Kim Cat Tuyen Vo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HucMSC-Derived Exosomes Mitigate the Age-Related Retardation of Fertility in Female Mice

(2020) Weijie Yang et al.   MOLECULAR THERAPY

Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing

(2020) Mila Maidarti et al.   Cells

Hippo signaling disruption and ovarian follicle activation in infertile patients

(2020) Aaron J.W. Hsueh et al.   FERTILITY AND STERILITY

In vivo and in vitro activation of dormant primordial follicles by EGF treatment in mouse and human

(2020) Jiawei Zhang et al.   Clinical and Translational Medicine

The effect of bpV(HOpic) on in vitro activation of primordial follicles in cultured swine ovarian cortical strips

(2019) Natalie Raffel et al.   REPRODUCTION IN DOMESTIC ANIMALS

Advances in human primordial follicle activation and premature ovarian insufficiency

(2019) Emmalee Ford et al.   REPRODUCTION

Drug-free In Vitro Activation (IVA) of follicles for infertility treatment in poor ovarian response patients with decreased ovarian reserve

(2019) Kazuhiro Kawamura et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Biopsying, fragmentation and autotransplantation of fresh ovarian cortical tissue in infertile women with diminished ovarian reserve

(2019) Stine Aagaard Lunding et al.   HUMAN REPRODUCTION

Drug- free in vitro activation of follicles and fresh tissue autotransplantation as a therapeutic option in primary ovarian insufficiency patients

(2019) Janisse Ferreri et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Current approaches for the treatment of premature ovarian failure with stem cell therapy

(2018) Golshan Sheikhansari et al.   BIOMEDICINE & PHARMACOTHERAPY

CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

(2018) Hao Yan et al.   BMC BIOLOGY

Biomechanics and mechanical signaling in the ovary: a systematic review

(2018) Jaimin S. Shah et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Insulin-like growth factor-1 (IGF-1) promotes primordial follicle growth and reduces DNA fragmentation through the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signalling pathway

(2018) Maria �. S. Bezerra et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Transplantation of UC-MSCs on collagen scaffold activates follicles in dormant ovaries of POF patients with long history of infertility

(2018) Lijun Ding et al.   Science China-Life Sciences

Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor

(2018) Chenyue Ding et al.   Stem Cell Research & Therapy

Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function

(2018) Yin Hu et al.   Theranostics

Pregnancy after drug-free in vitro activation of follicles and fresh tissue autotransplantation in primary ovarian insufficiency patient: a case report and literature review

(2018) F. Fabregues et al.   Journal of Ovarian Research

Inhibition of PTEN activates bovine non-growing follicles in vitro but increases DNA damage and reduces DNA repair response

(2018) Mila Maidarti et al.   HUMAN REPRODUCTION

Low expression of SEMA6C accelerates the primordial follicle activation in the neonatal mouse ovary

(2017) Su Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MAPK3/1 participates in the activation of primordial follicles through mTORC1-KITL signaling

(2017) Yu Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats

(2017) Hongqi Xin et al.   STROKE

Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism

(2017) Jia Li et al.   Stem Cell Research & Therapy

MiRNA-Sequence Indicates That Mesenchymal Stem Cells and Exosomes Have Similar Mechanism to Enhance Cardiac Repair

(2017) Lianbo Shao et al.   Biomed Research International

Spatial Characterization of Bioenergetics and Metabolism of Primordial to Preovulatory Follicles in Whole Ex Vivo Murine Ovary

(2016) R. Cinco et al.   BIOLOGY OF REPRODUCTION

Activation of dormant follicles

(2016) Kazuhiro Kawamura et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

In Vitro Activation of Follicles and Fresh Tissue Auto-transplantation in Primary Ovarian Insufficiency Patients

(2016) Jun Zhai et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis

(2016) Bo Wang et al.   MOLECULAR THERAPY

In Vitro Activation

(2016) Christina N. Cordeiro et al.   Reproductive Sciences

Sirtuins Link Inflammation and Metabolism

(2016) Vidula T. Vachharajani et al.   Journal of Immunology Research

New strategy for in vitro activation of primordial follicles with mTOR and PI3K stimulators

(2015) Xinhui Sun et al.   CELL CYCLE

Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy

(2015) Dah-Ching Ding et al.   CELL TRANSPLANTATION

Successful fertility preservation following ovarian tissue vitrification in patients with primary ovarian insufficiency

(2015) Nao Suzuki et al.   HUMAN REPRODUCTION

Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood

(2015) Hua Zhang et al.   HUMAN REPRODUCTION UPDATE

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

(2015) Jung-Soon Mo et al.   NATURE CELL BIOLOGY

Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells

(2015) Hua Zhang et al.   NATURE MEDICINE

LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool

(2015) Zong-Zhe Jiang et al.   Oncotarget

Short-Term PTEN Inhibition Improves In Vitro Activation of Primordial Follicles, Preserves Follicular Viability, and Restores AMH Levels in Cryopreserved Ovarian Tissue From Cancer Patients

(2015) Edurne Novella-Maestre et al.   PLoS One

Somatic Cells Initiate Primordial Follicle Activation and Govern the Development of Dormant Oocytes in Mice

(2014) Hua Zhang et al.   CURRENT BIOLOGY

Transforming Growth Factor-β Signaling Participates in the Maintenance of the Primordial Follicle Pool in the Mouse Ovary

(2014) Zheng-Pin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but compromises development of growing follicles

(2014) M. McLaughlin et al.   MOLECULAR HUMAN REPRODUCTION

The two classes of primordial follicles in the mouse ovary: their development, physiological functions and implications for future research

(2014) W. Zheng et al.   MOLECULAR HUMAN REPRODUCTION

mTORC1 Signaling in Oocytes Is Dispensable for the Survival of Primordial Follicles and for Female Fertility

(2014) Nagaraju Gorre et al.   PLoS One

Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain

(2014) N. Uesaka et al.   SCIENCE

Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions

(2013) Wenjing Zheng et al.   HUMAN MOLECULAR GENETICS

IGF-I Signaling Is Essential for FSH Stimulation of AKT and Steroidogenic Genes in Granulosa Cells

(2013) Ping Zhou et al.   MOLECULAR ENDOCRINOLOGY

Pharmacological Inhibition of mTORC1 Prevents Over-Activation of the Primordial Follicle Pool in Response to Elevated PI3K Signaling

(2013) Deepak Adhikari et al.   PLoS One

Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment

(2013) K. Kawamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ways and means that fine tune Sirt1 activity

(2013) Javier R. Revollo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mammalian Hippo signalling: a kinase network regulated by protein–protein interactions: Figure 1

(2012) Alexander Hergovich   BIOCHEMICAL SOCIETY TRANSACTIONS

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries

(2012) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways

(2012) Xiao-Yu Du et al.   Reproductive Biology and Endocrinology

Semaphorins in the development, homeostasis and disease of hormone systems

(2012) Paolo Giacobini et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Measuring anti-Müllerian hormone for the assessment of ovarian reserve: When and for whom is it indicated?

(2011) R.A. Anderson et al.   MATURITAS

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Functional roles of the phosphatidylinositol 3-kinases (PI3Ks) signaling in the mammalian ovary

(2011) Wenjing Zheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The IGF system

(2010) Marta Annunziata et al.   ACTA DIABETOLOGICA

Correlation of ovarian reserve tests with histologically determined primordial follicle number

(2010) Karl R. Hansen et al.   FERTILITY AND STERILITY

Proto-oncogene c-erbB2 initiates rat primordial follicle growth via PKC and MAPK pathways

(2010) Zheng Li-Ping et al.   Reproductive Biology and Endocrinology

Molecular Mechanisms Underlying the Activation of Mammalian Primordial Follicles

(2009) Deepak Adhikari et al.   ENDOCRINE REVIEWS

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

(2009) D. Adhikari et al.   HUMAN MOLECULAR GENETICS

Disruption of Tsc2 in oocytes leads to overactivation of the entire pool of primordial follicles

(2009) D. Adhikari et al.   MOLECULAR HUMAN REPRODUCTION

Production of offspring from a germline stem cell line derived from neonatal ovaries

(2009) Kang Zou et al.   NATURE CELL BIOLOGY

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility

(2009) H.-Y. Fan et al.   SCIENCE

The Interplay of Insulin-Like Growth Factors, Gonadotropins, and Endocrine Disruptors in Ovarian Follicular Development and Function

(2009) Jakub Kwintkiewicz et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Mechanisms maintaining the dormancy and survival of mammalian primordial follicles

(2009) Pradeep Reddy et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Tenets of PTEN Tumor Suppression

(2008) Leonardo Salmena et al.   CELL

The many faces of semaphorins: from development to pathology

(2008) L. Roth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

(2008) George B. John et al.   DEVELOPMENTAL BIOLOGY

LKB1; linking cell structure and tumor suppression

(2008) A F Hezel et al.   ONCOGENE

Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer

(2008) T. Boutros et al.   PHARMACOLOGICAL REVIEWS

Expression and activity of the 5'-adenosine monophosphate-activated protein kinase pathway in selected tissues during chicken embryonic development

(2008) M. Proszkowiec-Weglarz et al.   POULTRY SCIENCE

Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool

(2008) P. Reddy et al.   SCIENCE

Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep

(2008) Kate E Ryan et al.   Journal of Ovarian Research