MAPK3/1 participates in the activation of primordial follicles through mTORC1-KITL signaling

Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis

(2016) Reinhard Zech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood

(2015) Hua Zhang et al.   HUMAN REPRODUCTION UPDATE

ERK1/2 Activities Are Dispensable for Oocyte Growth but Are Required for Meiotic Maturation and Pronuclear Formation in Mouse

(2015) Yin-Li Zhang et al.   Journal of Genetics and Genomics

Somatic Cells Initiate Primordial Follicle Activation and Govern the Development of Dormant Oocytes in Mice

(2014) Hua Zhang et al.   CURRENT BIOLOGY

Transforming Growth Factor-β Signaling Participates in the Maintenance of the Primordial Follicle Pool in the Mouse Ovary

(2014) Zheng-Pin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC1 Signaling in Oocytes Is Dispensable for the Survival of Primordial Follicles and for Female Fertility

(2014) Nagaraju Gorre et al.   PLoS One

Epidermal Growth Factor Receptor Signaling-Dependent Calcium Elevation in Cumulus Cells Is Required for NPR2 Inhibition and Meiotic Resumption in Mouse Oocytes

(2013) Yakun Wang et al.   ENDOCRINOLOGY

Rapamycin-sensitive mTORC1 signaling is involved in physiological primordial follicle activation in mouse ovary

(2013) Yuanyuan Tong et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Pharmacological Inhibition of mTORC1 Prevents Over-Activation of the Primordial Follicle Pool in Response to Elevated PI3K Signaling

(2013) Deepak Adhikari et al.   PLoS One

Incorporation of Phosphatase Inhibitor in Culture Prompts Growth Initiation of Isolated Non-Growing Oocytes

(2013) Kanako Morohaku et al.   PLoS One

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The Safe Use of a PTEN Inhibitor for the Activation of Dormant Mouse Primordial Follicles and Generation of Fertilizable Eggs

(2012) Deepak Adhikari et al.   PLoS One

The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways

(2012) Xiao-Yu Du et al.   Reproductive Biology and Endocrinology

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

(2011) Brian Magnuson et al.   BIOCHEMICAL JOURNAL

Functional roles of the phosphatidylinositol 3-kinases (PI3Ks) signaling in the mammalian ovary

(2011) Wenjing Zheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Consequences of RAS and MAPK activation in the ovary: The good, the bad and the ugly

(2011) Heng-Yu Fan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Follicular assembly: mechanisms of action

(2011) Melissa E Pepling   REPRODUCTION

Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia

(2010) Camilla Evangelisti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Activation of dormant ovarian follicles to generate mature eggs

(2010) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proto-oncogene c-erbB2 initiates rat primordial follicle growth via PKC and MAPK pathways

(2010) Zheng Li-Ping et al.   Reproductive Biology and Endocrinology

Molecular Mechanisms Underlying the Activation of Mammalian Primordial Follicles

(2009) Deepak Adhikari et al.   ENDOCRINE REVIEWS

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

(2009) D. Adhikari et al.   HUMAN MOLECULAR GENETICS

MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility

(2009) H.-Y. Fan et al.   SCIENCE

Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries

(2009) Aileen F. Keating et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

(2008) George B. John et al.   DEVELOPMENTAL BIOLOGY

Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool

(2008) P. Reddy et al.   SCIENCE