Proteomics, Personalized Medicine and Cancer

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

(2021) Peter Kalev et al.   CANCER CELL

Extending the Depth of Human Plasma Proteome Coverage Using Simple Fractionation Techniques

(2021) Gurjeet Kaur et al.   JOURNAL OF PROTEOME RESEARCH

Cancer Moonshot 2.0

(2021) David B Agus et al.   LANCET ONCOLOGY

Cancer research needs a better map

(2021) Jesse S. Boehm et al.   NATURE

Application of Radiomics and Artificial Intelligence for Lung Cancer Precision Medicine

(2021) Ilke Tunali et al.   Cold Spring Harbor Perspectives in Medicine

Exploring the Emerging Role of the Gut Microbiota and Tumor Microenvironment in Cancer Immunotherapy

(2021) Qin Qiu et al.   Frontiers in Immunology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

(2021) Diwakar Davar et al.   SCIENCE

Adaptive Mechanisms of Tumor Therapy Resistance Driven by Tumor Microenvironment

(2021) Peijie Wu et al.   Frontiers in Cell and Developmental Biology

The Role of Artificial Intelligence in the Diagnosis and Prognosis of Renal Cell Tumors

(2021) Matteo Giulietti et al.   Diagnostics

Proteomic Profiling and Artificial Intelligence for Hepatocellular Carcinoma Translational Medicine

(2021) Nurbubu Moldogazieva et al.   Biomedicines

Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications

(2021) Hui Ming et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

(2020) Haopeng Xiao et al.   CELL

Review of Three-Dimensional Liquid Chromatography Platforms for Bottom-Up Proteomics

(2020) Van-An Duong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer

(2020) Abdullah Saleh Al-wajeeh et al.   PLoS One

Beyond mass spectrometry, the next step in proteomics

(2020) Winston Timp et al.   Science Advances

Comprehensive Review of Web Servers and Bioinformatics Tools for Cancer Prognosis Analysis

(2020) Hong Zheng et al.   Frontiers in Oncology

Single-cell analysis targeting the proteome

(2020) Mahmoud Labib et al.   Nature Reviews Chemistry

Bioinformatics combined with quantitative proteomics analyses and identification of potential biomarkers in cholangiocarcinoma

(2020) Zijian Da et al.   Cancer Cell International

Identification of noninvasive diagnostic biomarkers for hepatocellular carcinoma by urinary proteomics

(2020) Yinghua Zhao et al.   Journal of Proteomics

Proteomic and transcriptomic profiling of Pten gene‐knockout mouse model of prostate cancer

(2020) Jinhui Zhang et al.   PROSTATE

Data‐Independent Acquisition Mass Spectrometry‐Based Proteomics and Software Tools: A Glimpse in 2020

(2020) Fangfei Zhang et al.   PROTEOMICS

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Metaproteomics characterizes human gut microbiome function in colorectal cancer

(2020) Shuping Long et al.   npj Biofilms and Microbiomes

The status of proteomics as we enter the 2020s: Towards personalised/precision medicine

(2020) Edouard C. Nice   ANALYTICAL BIOCHEMISTRY

Using two peptide isotopologues as internal standards for the streamlined quantification of low-abundance proteins by immuno-MRM and immuno-MALDI

(2020) Sahar Ibrahim et al.   ANALYTICAL CHEMISTRY

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

(2020) Michael A. Gillette et al.   CELL

Integrative Proteomic Characterization of Human Lung Adenocarcinoma

(2020) Jun-Yu Xu et al.   CELL

A Comprehensive Proteomic SWATH-MS Workflow for Profiling Blood Extracellular Vesicles: A New Avenue for Glioma Tumour Surveillance

(2020) Susannah Hallal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Probiotic‑derived ferrichrome inhibits the growth of refractory pancreatic cancer cells

(2020) Akemi Kita et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Probing SWATH‐MS as a tool for proteome level quantification in a nonmodel fish

(2020) Alison A. Monroe et al.   Molecular Ecology Resources

Redox homeostasis maintained by GPX4 facilitates STING activation

(2020) Mutian Jia et al.   NATURE IMMUNOLOGY

Bacterial invaders drive CRC progression

(2020) Matthew Meyerson   Science Signaling

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

Strategies to enable large-scale proteomics for reproducible research

(2020) Rebecca C. Poulos et al.   Nature Communications

The Separation Sciences, the Front End to Proteomics. An Historical Perspective

(2020) Edouard C. Nice   BIOMEDICAL CHROMATOGRAPHY

Clinical trial design: Past, present, and future in the context of big data and precision medicine

(2020) Allen Li et al.   CANCER

LOXL4 Fosters an Immunosuppressive Microenvironment During Hepatocarcinogenesis

(2020) Hor‐Yue Tan et al.   HEPATOLOGY

Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin

(2020) Valentina Pagliara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project

(2020) Gilbert S. Omenn et al.   JOURNAL OF PROTEOME RESEARCH

Health-care inequality could deepen with precision oncology

(2020) Jyoti Madhusoodanan   NATURE

DIALib-QC an assessment tool for spectral libraries in data-independent acquisition proteomics

(2020) Mukul K. Midha et al.   Nature Communications

A high-stringency blueprint of the human proteome

(2020) Subash Adhikari et al.   Nature Communications

Integration of Online Omics-Data Resources for Cancer Research

(2020) Tonmoy Das et al.   Frontiers in Genetics

An Integrated Quantitative Proteomics Workflow for Cancer Biomarker Discovery and Validation in Plasma

(2020) Vipin Kumar et al.   Frontiers in Oncology

Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

(2020) Wei Zhao et al.   CANCER CELL

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

(2020) Francesca Petralia et al.   CELL

Surmounting cancer drug resistance: New insights from the perspective of N6-methyladenosine RNA modification

(2020) Bowen Li et al.   DRUG RESISTANCE UPDATES

Top-down proteomics: challenges, innovations, and applications in basic and clinical research

(2020) Kyle A. Brown et al.   Expert Review of Proteomics

‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures

(2020) Ewen Callaway   NATURE

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

(2020) Erez N. Baruch et al.   SCIENCE

TGF-β Mediated Immune Evasion in Cancer—Spotlight on Cancer-Associated Fibroblasts

(2020) Parisa Ghahremanifard et al.   Cancers

Proteomics of Colorectal Cancer: Tumors, Organoids, and Cell Cultures—A Minireview

(2020) Philip H. Lindhorst et al.   Frontiers in Molecular Biosciences

Translating proteomics big data into biomedical applications with computational modeling

(2020) Yudong Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

(2019) Kirsten L. Bryant et al.   NATURE MEDICINE

New clinical trial designs in the era of precision medicine

(2019) Elena Garralda et al.   Molecular Oncology

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

(2019) Mara Roxana Rubinstein et al.   EMBO REPORTS

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

(2019) Chengcheng Jin et al.   CELL

Targeted Proteomics Comes to the Benchside and the Bedside: Is it Ready for Us?

(2019) Anjali Arora et al.   BIOESSAYS

Optimization and Comparison of Information-Dependent Acquisition (IDA) to Sequential Window Acquisition of All Theoretical Fragment Ion Spectra (SWATH) for High-Resolution Mass Spectrometry in Clinical Toxicology

(2019) Jeffrey D. Whitman et al.   CLINICAL CHEMISTRY

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

(2019) Mark A. Eckert et al.   NATURE

Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning

(2019) Siegfried Gessulat et al.   NATURE METHODS

Effects of Intestinal Microbial–Elaborated Butyrate on Oncogenic Signaling Pathways

(2019) Jiezhong Chen et al.   Nutrients

Simulation of single-protein nanopore sensing shows feasibility for whole-proteome identification

(2019) Shilo Ohayon et al.   PLoS Computational Biology

The clinicopathological significance of heterogeneic Ezrin expression in PDC s of colorectal cancers

(2019) Akane Aikawa et al.   CANCER SCIENCE

Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples

(2019) Peng Lin et al.   Journal of Proteomics

Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

(2019) Lian He et al.   Journal of Biological Engineering

Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology

(2019) Subarna Palit et al.   Frontiers in Immunology

Prognostic value of biomarkers EpCAM and αB-crystallin associated with lymphatic metastasis in breast cancer by iTRAQ analysis

(2019) Liang Zeng et al.   BMC CANCER

Oncoproteomics: Current status and future opportunities

(2019) Yujia He et al.   CLINICA CHIMICA ACTA

The microbiome and cancer for clinicians

(2019) Sarah L. Picardo et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Proteomics Reveals Cell‐Surface Urokinase Plasminogen Activator Receptor Expression Impacts Most Hallmarks of Cancer

(2019) Seong Beom Ahn et al.   PROTEOMICS

Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel

(2019) Seong Beom Ahn et al.   Clinical Proteomics

Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia

(2019) Bader Alanazi et al.   LEUKEMIA

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

(2019) Gonçalo Rodrigues et al.   NATURE CELL BIOLOGY

Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies

(2019) Heeva Baharlou et al.   Frontiers in Immunology

FoxO3a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer

(2019) Michele Pellegrino et al.   Cancers

Biomarkers in Colorectal Cancer: The Role of Translational Proteomics Research

(2019) Bruno Augusto Alves Martins et al.   Frontiers in Oncology

Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy

(2019) Zuan-Fu Lim et al.   Journal of Hematology & Oncology

Proteomic investigation on bio-corona of Au, Ag and Fe nanoparticles for the discovery of triple negative breast cancer serum protein biomarkers

(2019) María del Pilar Chantada-Vázquez et al.   Journal of Proteomics

Revolutionizing Precision Oncology through Collaborative Proteogenomics and Data Sharing

(2018) Henry Rodriguez et al.   CELL

Biomarker definitions and their applications

(2018) Robert M Califf   EXPERIMENTAL BIOLOGY AND MEDICINE

Transformative Opportunities for Single-Cell Proteomics

(2018) Harrison Specht et al.   JOURNAL OF PROTEOME RESEARCH

Redox control in cancer development and progression

(2018) Valeska Helfinger et al.   MOLECULAR ASPECTS OF MEDICINE

Single-molecule peptide fingerprinting

(2018) Jetty van Ginkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leucine-rich alpha-2-glycoprotein-1 is up-regulated in colorectal cancer and is a tumor promoter

(2018) Qian Zhang et al.   OncoTargets and Therapy

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

(2018) Paula Díaz et al.   Frontiers in Microbiology

Metabolite identification in fecal microbiota transplantation mouse livers and combined proteomics with chronic unpredictive mild stress mouse livers

(2018) Bo Li et al.   Translational Psychiatry

A phase 1 trial extension to assess immunologic efficacy and safety of prime-boost vaccination with VXM01, an oral T cell vaccine against VEGFR2, in patients with advanced pancreatic cancer

(2018) Friedrich H. Schmitz-Winnenthal et al.   OncoImmunology

Fluorescence-based kinetic analysis of miniaturized protein microarrays

(2018) Heman Kumar Ramiya Ramesh Babu et al.   BIOSENSORS & BIOELECTRONICS

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

(2018) Fabian Coscia et al.   CELL

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

(2018) Ulrike Bruning et al.   Cell Metabolism

Proteomics and the microbiome: pitfalls and potential

(2018) Huafeng Lin et al.   Expert Review of Proteomics

Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial

(2018) Christina Ludwig et al.   Molecular Systems Biology

Differential Ion Mobility–Mass Spectrometry for Detailed Analysis of the Proteome

(2018) Daniel L. Winter et al.   TRENDS IN BIOTECHNOLOGY

Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids

(2018) Yuichi Abe et al.   Scientific Reports

Protocol for Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

(2018) Haiming Fang et al.   Biomed Research International

Susceptibility Testing of Bacteria Using Maldi-Tof Mass Spectrometry

(2018) Irene Burckhardt et al.   Frontiers in Microbiology

Recent Advances in Multidimensional Separation for Proteome Analysis

(2018) Huiming Yuan et al.   ANALYTICAL CHEMISTRY

Fecal microbiota transplantation in cancer management: Current status and perspectives

(2018) Danfeng Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Quiescin Sulfhydryl Oxidase 1 (QSOX1) Secreted by Lung Cancer Cells Promotes Cancer Metastasis

(2018) Hye-Jin Sung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemotherapy-Exacerbated Breast Cancer Metastasis: A Paradox Explainable by Dysregulated Adaptive-Response

(2018) Justin Middleton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures

(2018) Jagannath Swaminathan et al.   NATURE BIOTECHNOLOGY

Clinical potential of mass spectrometry-based proteogenomics

(2018) Bing Zhang et al.   Nature Reviews Clinical Oncology

Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress

(2018) Zhe Zhang et al.   Redox Biology

Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolism

(2018) Jemma Dunn et al.   EBioMedicine

Fecal Microbiota Transplantation Beneficially Regulates Intestinal Mucosal Autophagy and Alleviates Gut Barrier Injury

(2018) Saisai Cheng et al.   mSystems

Prospects and progress of Listeria-based cancer vaccines

(2017) Azam Bolhassani et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Drug-perturbation-based stratification of blood cancer

(2017) Sascha Dietrich et al.   JOURNAL OF CLINICAL INVESTIGATION

Evaluation of OK-432 Injection Therapy as Possible Primary Treatment of Intraoral Ranula

(2017) Michihide Kono et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Intracavitary bacillus Calmette-Guérin for Superficial Bladder Tumors

(2017) Michael J. Droller   JOURNAL OF UROLOGY

High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer

(2017) Paolo Cifani et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagy in the liver: functions in health and disease

(2017) Takashi Ueno et al.   Nature Reviews Gastroenterology & Hepatology

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

(2017) Suhas V Vasaikar et al.   NUCLEIC ACIDS RESEARCH

Dual role of autophagy in hallmarks of cancer

(2017) Shikha Satendra Singh et al.   ONCOGENE

Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

(2017) Valerie Chew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What is targeted proteomics? A concise revision of targeted acquisition and targeted data analysis in mass spectrometry

(2017) Eva Borràs et al.   PROTEOMICS

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

(2017) George S. Karagiannis et al.   Science Translational Medicine

Analytical Protein Microarrays: Advancements Towards Clinical Applications

(2017) Ursula Sauer   SENSORS

Ferrichrome identified from Lactobacillus casei ATCC334 induces apoptosis through its iron-binding site in gastric cancer cells

(2017) Masami Ijiri et al.   TUMOR BIOLOGY

Prediction of Chlamydia pneumoniae protein localization in host mitochondria and cytoplasm and possible involvements in lung cancer etiology: a computational approach

(2017) Aws Alshamsan et al.   SAUDI PHARMACEUTICAL JOURNAL

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

(2017) Ben C. Collins et al.   Nature Communications

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence

(2017) Alexandre Reuben et al.   Cancer Discovery

Successful identification of a predictive biomarker for lymph node metastasis in colorectal cancer using a proteomic approach

(2017) Koichiro Mori et al.   Oncotarget

Serological proteome analysis approach-based identification of ENO1 as a tumor-associated antigen and its autoantibody could enhance the sensitivity of CEA and CYFRA 21-1 in the detection of non-small cell lung cancer

(2017) Liping Dai et al.   Oncotarget

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer

(2017) Xiaoling Qian et al.   Oncotarget

RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma

(2017) Tianze Liu et al.   Theranostics

Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal Cancer

(2017) Alba Cristobal et al.   Cell Reports

Identification of MST1 as a potential early detection biomarker for colorectal cancer through a proteomic approach

(2017) Jiekai Yu et al.   Scientific Reports

Microbiome and Anticancer Immunosurveillance

(2016) Laurence Zitvogel et al.   CELL

Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome

(2016) Ulrike Kusebauch et al.   CELL

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

(2016) Hui Zhang et al.   CELL

HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3

(2016) K Yuan et al.   CELL DEATH AND DIFFERENTIATION

Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy

(2016) Moustafa R. K. Ali et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

Butyrate production from high-fiber diet protects against lymphoma tumor

(2016) Wei Wei et al.   LEUKEMIA & LYMPHOMA

Characterization of microbiome in bronchoalveolar lavage fluid of patients with lung cancer comparing with benign mass like lesions

(2016) Sang Hoon Lee et al.   LUNG CANCER

A proposal for validation of antibodies

(2016) Mathias Uhlen et al.   NATURE METHODS

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions

(2016) Ouajdi Felfoul et al.   Nature Nanotechnology

Complete Resolution of Retroperitoneal Lymphangioma with a Single Trial of OK-432 in an Infant

(2016) Claudio Olivieri et al.   Pediatrics and Neonatology

Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: Principle and applications

(2016) Adele Bourmaud et al.   PROTEOMICS

Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis

(2016) Hiroaki Konishi et al.   Nature Communications

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

(2016) Anna Prudova et al.   Cell Reports

Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies

(2016) Mohammad A. Jafri et al.   Genome Medicine

The Size of the Human Proteome: The Width and Depth

(2016) Elena A. Ponomarenko et al.   International Journal of Analytical Chemistry

Proteomics Moves into the Fast Lane

(2016) Nicholas M. Riley et al.   Cell Systems

AC1MMYR2 impairs high dose paclitaxel-induced tumor metastasis by targeting miR-21/CDK5 axis

(2015) Yu Ren et al.   CANCER LETTERS

Recent findings from the human proteome project: opening the mass spectrometry toolbox to advance cancer diagnosis, surveillance and treatment

(2015) David I Cantor et al.   Expert Review of Proteomics

Helicobacter pylori Update: Gastric Cancer, Reliable Therapy, and Possible Benefits

(2015) David Y. Graham   GASTROENTEROLOGY

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

The CPTAC Data Portal: A Resource for Cancer Proteomics Research

(2015) Nathan J. Edwards et al.   JOURNAL OF PROTEOME RESEARCH

Parallel reaction monitoring (PRM) and selected reaction monitoring (SRM) exhibit comparable linearity, dynamic range and precision for targeted quantitative HDL proteomics

(2015) Graziella E. Ronsein et al.   Journal of Proteomics

Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling

(2015) Jeffrey R. Whiteaker et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps

(2015) Tiannan Guo et al.   NATURE MEDICINE

DIA mass spectrometry

(2015) Allison Doerr   NATURE METHODS

Quantitative proteomics using SILAC: Principles, applications, and developments

(2015) Xiulan Chen et al.   PROTEOMICS

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest

(2015) Michela Capello et al.   Oncotarget

Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms

(2015) Kazufumi Honda et al.   Scientific Reports

Prognostic Value of Ezrin in Various Cancers: A Systematic Review and Updated Meta-analysis

(2015) Jianwei Li et al.   Scientific Reports

Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective

(2015) Alan Talevi   Frontiers in Pharmacology

Identification of ENO1 As a Potential Sputum Biomarker for Early-Stage Lung Cancer by Shotgun Proteomics

(2014) Lei Yu et al.   Clinical Lung Cancer

Super-SILAC: current trends and future perspectives

(2014) Anjana Shenoy et al.   Expert Review of Proteomics

Evaluation of Data-Dependent and -Independent Mass Spectrometric Workflows for Sensitive Quantification of Proteins and Phosphorylation Sites

(2014) Manuel Bauer et al.   JOURNAL OF PROTEOME RESEARCH

Proteogenomics: concepts, applications and computational strategies

(2014) Alexey I Nesvizhskii   NATURE METHODS

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer

(2014) F Aranda et al.   ONCOGENE

Tumor-targeting bacterial therapy: A potential treatment for oral cancer (Review)

(2014) SAI LIU et al.   Oncology Letters

Bifidobacteria Stabilize Claudins at Tight Junctions and Prevent Intestinal Barrier Dysfunction in Mouse Necrotizing Enterocolitis

(2013) Kelly R. Bergmann et al.   AMERICAN JOURNAL OF PATHOLOGY

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Chlamydia Infection Promotes Host DNA Damage and Proliferation but Impairs the DNA Damage Response

(2013) Cindrilla Chumduri et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Technical considerations for large-scale parallel reaction monitoring analysis

(2013) Sebastien Gallien et al.   Journal of Proteomics

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Insights into the phylogeny and coding potential of microbial dark matter

(2013) Christian Rinke et al.   NATURE

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells byLactobacillus caseiExtract

(2013) Dae Jong Han et al.   YONSEI MEDICAL JOURNAL

Emerging Techniques in Proteomics for Probing Nano–Bio Interactions

(2012) Zon W. Lai et al.   ACS Nano

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Redox Proteomics: Chemical Principles, Methodological Approaches and Biological/Biomedical Promises

(2012) Angela Bachi et al.   CHEMICAL REVIEWS

Microbial culturomics: paradigm shift in the human gut microbiome study

(2012) J.-C. Lagier et al.   CLINICAL MICROBIOLOGY AND INFECTION

Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

(2012) Ludovic C. Gillet et al.   MOLECULAR & CELLULAR PROTEOMICS

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

(2012) Sergei I. Grivennikov et al.   NATURE

Altered Plasma Apolipoprotein Modifications in Patients with Pancreatic Cancer: Protein Characterization and Multi-Institutional Validation

(2012) Kazufumi Honda et al.   PLoS One

MMS19 Assembles Iron-Sulfur Proteins Required for DNA Metabolism and Genomic Integrity

(2012) O. Stehling et al.   SCIENCE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer

(2012) C. Biot et al.   Science Translational Medicine

Bioengineered microbes in disease therapy

(2012) Adrienne W. Paton et al.   TRENDS IN MOLECULAR MEDICINE

Potential role of probiotics on colorectal cancer prevention

(2012) Mario Uccello et al.   BMC Surgery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Use of multiple reaction monitoring for multiplex analysis of colorectal cancer-associated proteins in human feces

(2011) Ching-Seng Ang et al.   ELECTROPHORESIS

Effects and mechanism of OK-432 therapy in various neck cystic lesions

(2010) Nobuo Ohta et al.   ACTA OTO-LARYNGOLOGICA

SILAC-based proteomic analysis to dissect the “histone modification signature” of human breast cancer cells

(2010) Alessandro Cuomo et al.   AMINO ACIDS

Listeria monocytogenes as a Vector for Anti-Cancer Therapies

(2010) Mark Tangney et al.   CURRENT GENE THERAPY

Treatments of various otolaryngological cystic diseases by OK-4321

(2010) Nobuo Ohta et al.   LARYNGOSCOPE

iTRAQ-based proteomic identification of leucine-rich  -2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases

(2009) S. Serada et al.   ANNALS OF THE RHEUMATIC DISEASES

Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix‐Assisted Laser Desorption Ionization Time‐of‐Flight Mass Spectrometry

(2009) Piseth Seng et al.   CLINICAL INFECTIOUS DISEASES

A Comparison of Labeling and Label-Free Mass Spectrometry-Based Proteomics Approaches

(2009) Vibhuti J. Patel et al.   JOURNAL OF PROTEOME RESEARCH

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

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Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function

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