Murine Macrophages Modulate Their Inflammatory Profile in Response to Gas Plasma-Inactivated Pancreatic Cancer Cells

Characterization of Macrophages and Osteoclasts in the Osteosarcoma Tumor Microenvironment at Diagnosis: New Perspective for Osteosarcoma Treatment?

(2021) Anne Gomez-Brouchet et al.   Cancers

Tumor cell metabolism correlates with resistance to gas plasma treatment: the evaluation of three dogmas

(2021) Sander Bekeschus et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting Redox Metabolism in Pancreatic Cancer

(2021) Nadine Abdel Hadi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gas Plasma Technology Augments Ovalbumin Immunogenicity and OT‐II T Cell Activation Conferring Tumor Protection in Mice

(2021) Ramona Clemen et al.   Advanced Science

Oxidation of Innate Immune Checkpoint CD47 on Cancer Cells with Non-Thermal Plasma

(2021) Abraham Lin et al.   Cancers

Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death

(2021) Naresh Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Argon Plasma Exposure Augments Costimulatory Ligands and Cytokine Release in Human Monocyte-Derived Dendritic Cells

(2021) Sander Bekeschus et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy

(2021) Maksudbek Yusupov et al.   Redox Biology

Tumor Cell–Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer

(2020) Shipra Das et al.   CANCER RESEARCH

Combination of Gas Plasma and Radiotherapy Has Immunostimulatory Potential and Additive Toxicity in Murine Melanoma Cells in Vitro

(2020) Gabriella Pasqual-Melo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of Two Kinase Inhibitors with Synergistic Toxicity with Low-Dose Hydrogen Peroxide in Colorectal Cancer Cells In vitro

(2020) Eric Freund et al.   Cancers

Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes

(2020) Thomas M. Pausch et al.   Scientific Reports

Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion

(2020) Sander Bekeschus et al.   Advanced Science

Gas Plasma-Treated Prostate Cancer Cells Augment Myeloid Cell Activity and Cytotoxicity

(2020) Sander Bekeschus et al.   Antioxidants

Oxidatively Modified Proteins: Cause and Control of Diseases

(2020) Ramona Clemen et al.   Applied Sciences-Basel

Risk Evaluation of EMT and Inflammation in Metastatic Pancreatic Cancer Cells Following Plasma Treatment

(2020) Eric Freund et al.   Frontiers in Physics

Effects of cold physical plasma on oral lichen planus: An in vitro study ( Effects of CAP on OLP )

(2020) Christian Seebauer et al.   ORAL DISEASES

Gas plasma irradiation of breast cancers promotes immunogenicity, tumor reduction, and an abscopal effect in vivo

(2020) Hamed Mahdikia et al.   OncoImmunology

Physical Plasma-Treated Skin Cancer Cells Amplify Tumor Cytotoxicity of Human Natural Killer (NK) Cells

(2020) Ramona Clemen et al.   Cancers

Inhibitory effect of non-thermal plasma synergistic Tegafur on pancreatic tumor cell line BxPc-3 proliferation

(2019) Zhengshi Chang et al.   Plasma Processes and Polymers

Blocking CXCLs–CXCR2 axis in tumor–stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment

(2019) Makoto Sano et al.   Oncogenesis

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

(2019) Brooke Benner et al.   Journal for ImmunoTherapy of Cancer

RAW 264.7 Macrophage Polarization by Pancreatic Cancer Cells – A Model for Studying Tumour-promoting Macrophages

(2019) AYDAR KHABIPOV et al.   ANTICANCER RESEARCH

Non-thermal plasma-induced immunogenic cell death in cancer

(2019) Marian Khalili et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Elevated H2AX Phosphorylation Observed with kINPen Plasma Treatment Is Not Caused by ROS-Mediated DNA Damage but Is the Consequence of Apoptosis

(2019) Sander Bekeschus et al.   Oxidative Medicine and Cellular Longevity

Risk Assessment of kINPen Plasma Treatment of Four Human Pancreatic Cancer Cell Lines with Respect to Metastasis

(2019) Sander Bekeschus et al.   Cancers

ROS from Physical Plasmas: Redox Chemistry for Biomedical Therapy

(2019) Angela Privat-Maldonado et al.   Oxidative Medicine and Cellular Longevity

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

(2019) Jinthe Van Loenhout et al.   Cancers

Cold physical plasma treated buffered saline solution as effective agent against pancreatic cancer cells

(2018) Sander Bekeschus et al.   Anti-Cancer Agents in Medicinal Chemistry

TGF-β1/TβRII/Smad3 signaling pathway promotes VEGF expression in oral squamous cell carcinoma tumor-associated macrophages

(2018) Haibin Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Physical plasma and leukocytes – immune or reactive?

(2018) Sander Bekeschus et al.   BIOLOGICAL CHEMISTRY

3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment

(2018) Sofia P. Rebelo et al.   BIOMATERIALS

High throughput image cytometry micronucleus assay to investigate the presence or absence of mutagenic effects of cold physical plasma

(2018) Sander Bekeschus et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy

(2018) Jinyang Li et al.   IMMUNITY

The kINPen—a review on physics and chemistry of the atmospheric pressure plasma jet and its applications

(2018) Stephan Reuter et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Itraconazole inhibits invasion and migration of pancreatic cancer cells by suppressing TGF-β/SMAD2/3 signaling

(2018) Ke Chen et al.   ONCOLOGY REPORTS

Chemical fingerprints of cold physical plasmas – an experimental and computational study using cysteine as tracer compound

(2018) J.-W. Lackmann et al.   Scientific Reports

Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy

(2018) Adriana Albini et al.   Frontiers in Immunology

Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1

(2018) Ya-Ling Hsu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor microenvironment participates in metastasis of pancreatic cancer

(2018) Bo Ren et al.   Molecular Cancer

Cold Physical Plasma Selectively Elicits Apoptosis in Murine Pancreatic Cancer Cells In Vitro and In Ovo

(2018) KIM ROUVEN LIEDTKE et al.   ANTICANCER RESEARCH

The clinical role of the TME in solid cancer

(2018) Nicolas A. Giraldo et al.   BRITISH JOURNAL OF CANCER

RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer

(2018) Wei Wang et al.   CANCER CELL

From Friend to Enemy: Dissecting the Functional Alteration of Immunoregulatory Components during Pancreatic Tumorigenesis

(2018) Hui-Ching Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet

(2017) Anke Schmidt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TGF-β in pancreatic cancer initiation and progression: two sides of the same coin

(2017) Wei Shen et al.   Cell and Bioscience

NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine

(2017) Almohanad A. Alkayyal et al.   Cancer Immunology Research

Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity

(2017) Louise A. Elliott et al.   Frontiers in Immunology

Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype

(2017) Simone Borgoni et al.   OncoImmunology

Non-thermal plasma-treated solution demonstrates antitumor activity against pancreatic cancer cells in vitro and in vivo

(2017) Kim Rouven Liedtke et al.   Scientific Reports

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

(2016) Colin W. Steele et al.   CANCER CELL

Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis

(2016) Li Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Neutrophil extracellular trap formation is elicited in response to cold physical plasma

(2016) Sander Bekeschus et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression

(2016) Lena Seifert et al.   NATURE

Durable antitumor responses to CD47 blockade require adaptive immune stimulation

(2016) Jonathan T. Sockolosky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting tumor-associated macrophages to combat pancreatic cancer

(2016) Ran Cui et al.   Oncotarget

Investigating the Mutagenicity of a Cold Argon-Plasma Jet in an HET-MN Model

(2016) Susanne Kluge et al.   PLoS One

Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer

(2015) Freya A. Goumas et al.   INTERNATIONAL JOURNAL OF CANCER

Effectiveness of plasma treatment on pancreatic cancer cells

(2015) NORIFUMI HATTORI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

On the plasma chemistry of a cold atmospheric argon plasma jet with shielding gas device

(2015) Ansgar Schmidt-Bleker et al.   PLASMA SOURCES SCIENCE & TECHNOLOGY

The immunocytokine NHS-IL12 as a potential cancer therapeutic

(2015) Jonathan Fallon et al.   Oncotarget

Non-thermal atmospheric pressure plasma induces apoptosis in oral cavity squamous cell carcinoma: Involvement of DNA-damage-triggering sub-G1 arrest via the ATM/p53 pathway

(2014) Jae Won Chang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Osteopontin Shapes Immunosuppression in the Metastatic Niche

(2014) Sabina Sangaletti et al.   CANCER RESEARCH

Interleukin-6: a villain in the drama of pancreatic cancer development and progression

(2014) Reinhild Holmer et al.   Hepatobiliary & Pancreatic Diseases International

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis

(2014) Ole Helm et al.   INTERNATIONAL JOURNAL OF CANCER

Low-temperature plasma-induced antiproliferative effects on multi-cellular tumor spheroids

(2014) Joseph-Marie Plewa et al.   NEW JOURNAL OF PHYSICS

Interleukin-6 in inflammatory and malignant diseases of the pancreas

(2014) Marina Lesina et al.   SEMINARS IN IMMUNOLOGY

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

(2013) Y Ino et al.   BRITISH JOURNAL OF CANCER

Inflammatory cytokines in human pancreatic cancer

(2013) Rozita Roshani et al.   CANCER LETTERS

Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis

(2013) D. E. Sanford et al.   CLINICAL CANCER RESEARCH

Cold atmospheric plasma, a new strategy to induce senescence in melanoma cells

(2013) Stephanie Arndt et al.   EXPERIMENTAL DERMATOLOGY

Induction of M2-macrophages by tumour cells and tumour growth promotion by M2-macrophages: A quid pro quo in pancreatic cancer

(2013) L.I. Partecke et al.   PANCREATOLOGY

Targeting the Shift from M1 to M2 Macrophages in Experimental Autoimmune Encephalomyelitis Mice Treated with Fasudil

(2013) Chunyun Liu et al.   PLoS One

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Cytokine Network: New Targeted Therapy for Pancreatic Cancer

(2012) Yoichi Matsuo et al.   CURRENT PHARMACEUTICAL DESIGN

Effects of a Non Thermal Plasma Treatment Alone or in Combination with Gemcitabine in a MIA PaCa2-luc Orthotopic Pancreatic Carcinoma Model

(2012) Laura Brullé et al.   PLoS One

Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

(2011) Mario A. Shields et al.   BIOCHEMICAL JOURNAL

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

Overcoming drug resistance in pancreatic cancer

(2011) Jiang Long et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells

(2010) Chul-Ho Kim et al.   APPLIED PHYSICS LETTERS

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

(2009) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL RESEARCH

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Most Pancreatic Cancer Resections are R1 Resections

(2008) Irene Esposito et al.   ANNALS OF SURGICAL ONCOLOGY

Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression

(2008) Naoki Itano et al.   CANCER SCIENCE

Aquaporins—new players in cancer biology

(2008) A. S. Verkman et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS