Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

Non‐Thermal Plasma as a Unique Delivery System of Short‐Lived Reactive Oxygen and Nitrogen Species for Immunogenic Cell Death in Melanoma Cells

(2019) Abraham Lin et al.   Advanced Science

Targeting dendritic cells in pancreatic ductal adenocarcinoma

(2018) Anton Deicher et al.   Cancer Cell International

Inactivation of human pancreatic ductal adenocarcinoma with atmospheric plasma treated media and water: a comparative study

(2018) Naresh Kumar et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Immune therapies in pancreatic ductal adenocarcinoma: Where are we now?

(2018) Marc Hilmi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Non-thermal plasma induces immunogenic cell death in vivo in murine CT26 colorectal tumors

(2018) Abraham Lin et al.   OncoImmunology

Cancer immunoediting and resistance to T cell-based immunotherapy

(2018) Jake S. O’Donnell et al.   Nature Reviews Clinical Oncology

Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress

(2017) Abraham Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells

(2017) Jonas R.M. Van Audenaerde et al.   Oncotarget

Functions of pancreatic stellate cell-derived soluble factors in the microenvironment of pancreatic ductal carcinoma

(2017) Qi Wu et al.   Oncotarget

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

(2017) Jorrit De Waele et al.   OncoImmunology

The Specific Vulnerabilities of Cancer Cells to the Cold Atmospheric Plasma-Stimulated Solutions

(2017) Dayun Yan et al.   Scientific Reports

Non-thermal plasma-treated solution demonstrates antitumor activity against pancreatic cancer cells in vitro and in vivo

(2017) Kim Rouven Liedtke et al.   Scientific Reports

Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation

(2016) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells

(2016) Shin Hamada et al.   DIGESTIVE DISEASES AND SCIENCES

Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells

(2016) Stijn Vermeylen et al.   Plasma Processes and Polymers

Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma

(2016) Abhishek D. Garg et al.   Science Translational Medicine

Cold atmospheric plasma, a novel promising anti-cancer treatment modality

(2016) Dayun Yan et al.   Oncotarget

Human CD1c+ DCs are critical cellular mediators of immune responses induced by immunogenic cell death

(2016) Stefania Di Blasio et al.   OncoImmunology

Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors

(2015) A. Patnaik et al.   CLINICAL CANCER RESEARCH

Strategies to relieve immunosuppression in pancreatic cancer

(2015) Max Schnurr et al.   Immunotherapy

Addressing the challenges of pancreatic cancer: Future directions for improving outcomes

(2015) Manuel Hidalgo et al.   PANCREATOLOGY

Targeting the TGFβ pathway for cancer therapy

(2015) Cindy Neuzillet et al.   PHARMACOLOGY & THERAPEUTICS

Uniform Nanosecond Pulsed Dielectric Barrier Discharge Plasma Enhances Anti-Tumor Effects by Induction of Immunogenic Cell Death in Tumors and Stimulation of Macrophages

(2015) Abraham Lin et al.   Plasma Processes and Polymers

Update on the management of pancreatic cancer: Surgery is not enough

(2015) Daniel Ansari et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies

(2015) E. Gabriela Chiorean et al.   Drug Design Development and Therapy

Cancer-Associated Fibroblasts from Lung Tumors Maintain Their Immunosuppressive Abilities after High-Dose Irradiation

(2015) Laia Gorchs et al.   Frontiers in Oncology

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

(2015) Sofia R. Gameiro et al.   Oncotarget

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Hydrogen peroxide: A central player in physical plasma-induced oxidative stress in human blood cells

(2014) S. Bekeschus et al.   FREE RADICAL RESEARCH

High hydrostatic pressure induces immunogenic cell death in human tumor cells

(2014) Jitka Fucikova et al.   INTERNATIONAL JOURNAL OF CANCER

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

(2014) Roy S. Herbst et al.   NATURE

The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration

(2014) Jennifer Watt et al.   OncoImmunology

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

(2013) Abhishek D. Garg et al.   Autophagy

The stromal compartments in pancreatic cancer: Are there any therapeutic targets?

(2013) Serena Lunardi et al.   CANCER LETTERS

Tumour–stroma interactions in pancreatic ductal adenocarcinoma: Rationale and current evidence for new therapeutic strategies

(2013) V. Heinemann et al.   CANCER TREATMENT REVIEWS

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic cancer-associated stellate cells

(2013) Thomas A Mace et al.   OncoImmunology

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo

(2012) Lars Ivo Partecke et al.   BMC CANCER

The Pancreas Cancer Microenvironment

(2012) C. Feig et al.   CLINICAL CANCER RESEARCH

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin

(2011) Abhishek D. Garg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Effects of Non-Thermal Plasma on Mammalian Cells

(2011) Sameer Kalghatgi et al.   PLoS One

Poly(I:C) Enhances the Susceptibility of Leukemic Cells to NK Cell Cytotoxicity and Phagocytosis by DC

(2011) Eva Lion et al.   PLoS One

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

CD91-dependent programming of T-helper cell responses following heat shock protein immunization

(2011) Sudesh Pawaria et al.   Nature Communications

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

(2010) Richard E. Royal et al.   JOURNAL OF IMMUNOTHERAPY

Dendritic cells and immunity against cancer

(2010) K. Palucka et al.   JOURNAL OF INTERNAL MEDICINE