Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

Receptors for pro‐resolving mediators are increased in Alzheimer's disease brain

(2020) Ceren Emre et al.   BRAIN PATHOLOGY

Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model

(2020) Lynn van Olst et al.   NEUROBIOLOGY OF AGING

N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease

(2020) Ju Youn Lee et al.   Nature Communications

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

(2020) Laura Sebastian Monasor et al.   eLife

Maresin 1 attenuates pro‐inflammatory activation induced by β‐amyloid and stimulates its uptake

(2020) Ying Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer’s Disease

(2019) Joseph O. Ojo et al.   Frontiers in Neuroscience

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

(2019) Antonio Boza-Serrano et al.   ACTA NEUROPATHOLOGICA

Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease

(2019) Chih-Chieh Tao et al.   CELL DEATH AND DIFFERENTIATION

The Appropriate Marker for Astrocytes: Comparing the Distribution and Expression of Three Astrocytic Markers in Different Mouse Cerebral Regions

(2019) Zengli Zhang et al.   Biomed Research International

Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy

(2019) Tiffany Wu et al.   Cell Reports

Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

(2019) Gijs Kooij et al.   HAEMATOLOGICA

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors

(2019) Khanh V. Do et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease

(2018) Alpdogan Kantarci et al.   EXPERIMENTAL NEUROLOGY

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

(2018) Darin Lanjakornsiripan et al.   Nature Communications

The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

(2018) Anne Troldborg et al.   Frontiers in Immunology

Disturbed Choline Plasmalogen and Phospholipid Fatty Acid Concentrations in Alzheimer's Disease Prefrontal Cortex

(2018) Miki Igarashi et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Stephen C. Cunnane et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebrospinal Fluid Level of YKL-40 Protein in Preclinical and Prodromal Alzheimer's Disease

(2018) Anna Antonell et al.   JOURNAL OF ALZHEIMERS DISEASE

The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease

(2018) Stephanie Ziegler-Waldkirch et al.   Frontiers in Cellular Neuroscience

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

(2017) Marta Querol-Vilaseca et al.   Journal of Neuroinflammation

TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

(2017) Honghua Zheng et al.   JOURNAL OF NEUROSCIENCE

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

(2017) Franc Llorens et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner

(2017) Juan Pablo Palavicini et al.   Acta Neuropathologica Communications

Annexin A1 restores Aβ1-42-induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway

(2016) Jong-Chan Park et al.   AGING CELL

TREM2/DAP12 Signal Elicits Proinflammatory Response in Microglia and Exacerbates Neuropathic Pain

(2016) M. Kobayashi et al.   JOURNAL OF NEUROSCIENCE

Cognitive deficits in single App knock-in mouse models

(2016) Akira Masuda et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Resolution of Inflammation: What Controls Its Onset?

(2016) Michelle A. Sugimoto et al.   Frontiers in Immunology

Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants

(2016) Robert J. Shmookler Reis et al.   Aging-US

Resolution of inflammation is altered in Alzheimer's disease

(2015) Xiuzhe Wang et al.   Alzheimers & Dementia

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

TREM2 sustains microglial expansion during aging and response to demyelination

(2015) Pietro Luigi Poliani et al.   JOURNAL OF CLINICAL INVESTIGATION

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

(2015) Mingqin Zhu et al.   MOLECULAR NEUROBIOLOGY

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

(2015) Hong Lian et al.   NEURON

TMEM119 marks a subset of microglia in the human brain

(2015) Jun-ichi Satoh et al.   NEUROPATHOLOGY

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

(2014) G. Kleinberger et al.   Science Translational Medicine

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Elevated Galectin-3 Levels in the Serum of Patients With Alzheimer's Disease

(2013) Xuexin Wang et al.   American Journal of Alzheimers Disease and Other Dementias

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Sodium channels and microglial function

(2011) Joel A. Black et al.   EXPERIMENTAL NEUROLOGY

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

Interleukin-5 and IL-5 receptor in health and diseases

(2011) Kiyoshi TAKATSU   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

(2010) Giuseppe Astarita et al.   PLoS One

Selective Vulnerability of Neurons in Layer II of the Entorhinal Cortex during Aging and Alzheimer's Disease

(2010) Alexis M. Stranahan et al.   NEURAL PLASTICITY

Requirement of JNK-Mediated Phosphorylation for Translocation of Group IVA Phospholipase A2 to Phagosomes in Human Macrophages

(2009) J. Casas et al.   JOURNAL OF IMMUNOLOGY

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

(2009) J Chapuis et al.   MOLECULAR PSYCHIATRY

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE