Diversity of astrocyte functions and phenotypes in neural circuits

Large-scale recording of astrocyte activity

(2015) Axel Nimmerjahn et al.   CURRENT OPINION IN NEUROBIOLOGY

Ca2+ signaling in astrocytes from Ip3r2 −/− mice in brain slices and during startle responses in vivo

(2015) Rahul Srinivasan et al.   NATURE NEUROSCIENCE

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Astrocyte Calcium Signaling: From Observations to Functions and the Challenges Therein

(2015) Baljit S. Khakh et al.   Cold Spring Harbor Perspectives in Biology

Astrocyte Regulation of Synaptic Behavior

(2014) Nicola J. Allen   Annual Review of Cell and Developmental Biology

Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability

(2014) Yann Bernardinelli et al.   CURRENT BIOLOGY

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

(2014) Suzana Herculano-Houzel   GLIA

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Structural and Functional Plasticity of Astrocyte Processes and Dendritic Spine Interactions

(2014) A. Perez-Alvarez et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Gq-GPCR-Linked IP3R-Dependent Ca2+ Signaling Does Not Mediate Neurovascular Coupling in Mouse Visual Cortex In Vivo

(2014) D. E. Bonder et al.   JOURNAL OF NEUROSCIENCE

VGluT1+ Neuronal Glutamatergic Signaling Regulates Postnatal Developmental Maturation of Cortical Protoplasmic Astroglia

(2014) L. Morel et al.   JOURNAL OF NEUROSCIENCE

Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

(2014) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

Astrocyte calcium signalling orchestrates neuronal synchronization in organotypic hippocampal slices

(2014) Takuya Sasaki et al.   JOURNAL OF PHYSIOLOGY-LONDON

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

(2014) Anna V. Molofsky et al.   NATURE

Interneuron cell types are fit to function

(2014) Adam Kepecs et al.   NATURE

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

(2014) Ulrike Pannasch et al.   NATURE NEUROSCIENCE

Conditions and Constraints for Astrocyte Calcium Signaling in the Hippocampal Mossy Fiber Pathway

(2014) Martin D. Haustein et al.   NEURON

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Imaging Activity in Neurons and Glia with a Polr2a-Based and Cre-Dependent GCaMP5G-IRES-tdTomato Reporter Mouse

(2014) J. Michael Gee et al.   NEURON

Norepinephrine Controls Astroglial Responsiveness to Local Circuit Activity

(2014) Martin Paukert et al.   NEURON

Neuron-Glia Interactions through the Heartless FGF Receptor Signaling Pathway Mediate Morphogenesis of Drosophila Astrocytes

(2014) Tobias Stork et al.   NEURON

Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

(2014) Milos Pekny et al.   PHYSIOLOGICAL REVIEWS

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Astrocyte Development and Heterogeneity

(2014) Omer Ali Bayraktar et al.   Cold Spring Harbor Perspectives in Biology

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model

(2014) Andrea Delekate et al.   Nature Communications

In Vivo Visualization of Subtle, Transient, and Local Activity of Astrocytes Using an Ultrasensitive Ca2+ Indicator

(2014) Kazunori Kanemaru et al.   Cell Reports

Calcium-induced outgrowth of astrocytic peripheral processes requires actin binding by Profilin-1

(2013) Dmitry Molotkov et al.   CELL CALCIUM

α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice

(2013) Fengfei Ding et al.   CELL CALCIUM

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses

(2013) Eiji Shigetomi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

(2013) I. B. Wanner et al.   JOURNAL OF NEUROSCIENCE

TRPA1 Channels Are Regulators of Astrocyte Basal Calcium Levels and Long-Term Potentiation via Constitutive D-Serine Release

(2013) E. Shigetomi et al.   JOURNAL OF NEUROSCIENCE

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4

(2013) Eric J. Benner et al.   NATURE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

(2013) Sophia Bardehle et al.   NATURE NEUROSCIENCE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years

(2013) Marc R. Freeman et al.   NEURON

Endogenous Positive Allosteric Modulation of GABAA Receptors by Diazepam binding inhibitor

(2013) Catherine A. Christian et al.   NEURON

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses

(2013) K. M. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes potentiate GABAergic transmission in the thalamic reticular nucleus via endozepine signaling

(2013) C. A. Christian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NIH BRAIN Initiative

(2013) T. R. Insel et al.   SCIENCE

Functional imaging in freely moving animals

(2012) Jason ND Kerr et al.   CURRENT OPINION IN NEUROBIOLOGY

Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

(2012) M. E. Hamby et al.   JOURNAL OF NEUROSCIENCE

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

A Cre-Dependent GCaMP3 Reporter Mouse for Neuronal Imaging In Vivo

(2012) H. A. Zariwala et al.   JOURNAL OF NEUROSCIENCE

Bergmann Glial AMPA Receptors Are Required for Fine Motor Coordination

(2012) A. S. Saab et al.   SCIENCE

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

(2012) H.-H. Tsai et al.   SCIENCE

Astrocytes Mediate In Vivo Cholinergic-Induced Synaptic Plasticity

(2012) Marta Navarrete et al.   PLOS BIOLOGY

Calcium Signaling and Gliotransmission in Normal vs. Reactive Astrocytes

(2012) Cendra Agulhon et al.   Frontiers in Pharmacology

Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses

(2011) Aude Panatier et al.   CELL

Bulk Loading of Calcium Indicator Dyes to Study Astrocyte Physiology: Key Limitations and Improvements Using Morphological Maps

(2011) A. M. B. Reeves et al.   JOURNAL OF NEUROSCIENCE

Astrocyte Calcium Signaling Transforms Cholinergic Modulation to Cortical Plasticity In Vivo

(2011) N. Takata et al.   JOURNAL OF NEUROSCIENCE

Signaling Pathways in Reactive Astrocytes, a Genetic Perspective

(2011) Wenfei Kang et al.   MOLECULAR NEUROBIOLOGY

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

Local Ca2+ detection and modulation of synaptic release by astrocytes

(2011) Maria Amalia Di Castro et al.   NATURE NEUROSCIENCE

Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters

(2011) Eiji Shigetomi et al.   Neuron Glia Biology

Structural Remodeling of Astrocytes in the Injured CNS

(2011) Daniel Sun et al.   NEUROSCIENTIST

Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors

(2011) M. Lavialle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic regulation of cortical UP states

(2011) K. E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GFAP in health and disease

(2011) J. Middeldorp et al.   PROGRESS IN NEUROBIOLOGY

Action-Potential Modulation During Axonal Conduction

(2011) T. Sasaki et al.   SCIENCE

Genetic Mouse Models of Huntington's Disease: Focus on Electrophysiological Mechanisms

(2010) Carlos Cepeda et al.   ASN Neuro

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Astrocyte heterogeneity: an underappreciated topic in neurobiology

(2010) Ye Zhang et al.   CURRENT OPINION IN NEUROBIOLOGY

Morphological plasticity of the rat supraoptic nucleus - cellular consequences

(2010) Stéphane H. R. Oliet et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

In Vivo Intracellular Recording Suggests That Gray Matter Astrocytes in Mature Cerebral Cortex and Hippocampus Are Electrophysiologically Homogeneous

(2010) T. Mishima et al.   JOURNAL OF NEUROSCIENCE

Sonic Hedgehog Regulates Discrete Populations of Astrocytes in the Adult Mouse Forebrain

(2010) A. D. R. Garcia et al.   JOURNAL OF NEUROSCIENCE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Regulation of synaptic connectivity by glia

(2010) Cagla Eroglu et al.   NATURE

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

A genetically targeted optical sensor to monitor calcium signals in astrocyte processes

(2010) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Functions of Mature Mammalian Astrocytes: A Current View

(2010) Harold K. Kimelberg   NEUROSCIENTIST

Hippocampal Short- and Long-Term Plasticity Are Not Modulated by Astrocyte Ca2+ Signaling

(2010) C. Agulhon et al.   SCIENCE

Specification and Morphogenesis of Astrocytes

(2010) M. R. Freeman   SCIENCE

Astrocytes Control Breathing Through pH-Dependent Release of ATP

(2010) A. V. Gourine et al.   SCIENCE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Synaptic potentiation induces increased glial coverage of excitatory synapses in CA1 hippocampus

(2009) Irina Lushnikova et al.   HIPPOCAMPUS

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivo

(2009) Stan D. Atkin et al.   JOURNAL OF NEUROSCIENCE METHODS

Neuroscience: Glia — more than just brain glue

(2009) Nicola J. Allen et al.   NATURE

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Motor Behavior Activates Bergmann Glial Networks

(2009) Axel Nimmerjahn et al.   NEURON

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

(2009) Jennifer Bradford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Sorting Out Astrocyte Physiology from Pharmacology

(2008) Todd A. Fiacco et al.   Annual Review of Pharmacology and Toxicology

Identification of Positionally Distinct Astrocyte Subtypes whose Identities Are Specified by a Homeodomain Code

(2008) Christian Hochstim et al.   CELL

Locus Coeruleus α-Adrenergic–Mediated Activation of Cortical Astrocytes In Vivo

(2008) Lane K. Bekar et al.   CEREBRAL CORTEX

Functional implications for Kir4.1 channels in glial biology: from K+buffering to cell differentiation

(2008) Michelle L. Olsen et al.   JOURNAL OF NEUROCHEMISTRY

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

Loss of IP3 Receptor-Dependent Ca2+ Increases in Hippocampal Astrocytes Does Not Affect Baseline CA1 Pyramidal Neuron Synaptic Activity

(2008) J. Petravicz et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

What Is the Role of Astrocyte Calcium in Neurophysiology?

(2008) Cendra Agulhon et al.   NEURON