The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease
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Title
The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease
Authors
Keywords
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Journal
Frontiers in Cellular Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-12-11
DOI
10.3389/fncel.2018.00473
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Note: Only part of the references are listed.- BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology
- (2018) Finn Peters et al. ACTA NEUROPATHOLOGICA
- Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function
- (2018) Kaichuan Zhu et al. BIOLOGICAL PSYCHIATRY
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions
- (2018) Xiangyou Hu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model
- (2018) Alfonso Grimaldi et al. Cell Death & Disease
- Environmental enrichment reverses Aβ pathology during pregnancy in a mouse model of Alzheimer’s disease
- (2018) Stephanie Ziegler-Waldkirch et al. Acta Neuropathologica Communications
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- Dark microglia: A new phenotype predominantly associated with pathological states
- (2016) Kanchan Bisht et al. GLIA
- Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate
- (2016) Ting Yang et al. JOURNAL OF NEUROSCIENCE
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- Phosphorylation of amyloid beta (Aβ) peptides – A trigger for formation of toxic aggregates in Alzheimer's disease
- (2016) Sathish Kumar et al. Aging-US
- Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and Function
- (2016) Maria I. Fonseca et al. PLoS One
- Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions
- (2015) Severin Filser et al. BIOLOGICAL PSYCHIATRY
- NG2-glia and their functions in the central nervous system
- (2015) L. Dimou et al. GLIA
- Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
- (2015) Nabil N. Dagher et al. Journal of Neuroinflammation
- Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory
- (2015) Anna G Orr et al. NATURE NEUROSCIENCE
- Microglia: Dynamic Mediators of Synapse Development and Plasticity
- (2015) Yuwen Wu et al. TRENDS IN IMMUNOLOGY
- Impairment of in vivo calcium signaling in amyloid plaque-associated microglia
- (2014) Bianca Brawek et al. ACTA NEUROPATHOLOGICA
- Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model
- (2014) Mario M. Dorostkar et al. BRAIN
- Correction: Fowler et al., Genetic Modulation of Soluble A Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease
- (2014) JOURNAL OF NEUROSCIENCE
- Targeting the β secretase BACE1 for Alzheimer's disease therapy
- (2014) Riqiang Yan et al. LANCET NEUROLOGY
- GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease
- (2014) Seonmi Jo et al. NATURE MEDICINE
- Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
- (2014) Yang Zhan et al. NATURE NEUROSCIENCE
- Postsynaptic Target Specific Synaptic Dysfunctions in the CA3 Area of BACE1 Knockout Mice
- (2014) Hui Wang et al. PLoS One
- Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model
- (2014) Andrea Delekate et al. Nature Communications
- BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
- (2014) Robert Vassar Alzheimers Research & Therapy
- Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease
- (2013) Joanna F. McCarter et al. ACTA NEUROPATHOLOGICA
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease
- (2013) Alberto Serrano-Pozo et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Chronic γ-secretase inhibition reduces amyloid plaque-associated instability of pre- and postsynaptic structures
- (2013) S Liebscher et al. MOLECULAR PSYCHIATRY
- Emerging roles of astrocytes in neural circuit development
- (2013) Laura E. Clarke et al. NATURE REVIEWS NEUROSCIENCE
- Memorable Trends
- (2013) Yadin Dudai et al. NEURON
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature
- (2013) T. Wyss-Coray et al. Cold Spring Harbor Perspectives in Medicine
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Novel BACE1 inhibitor, E2609, lowers Aβ levels in the cerebrospinal fluid and plasma in nonhuman primates
- (2012) Fiona Lucas et al. Alzheimers & Dementia
- The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease
- (2012) Alexander H. Stephan et al. Annual Review of Neuroscience
- TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation
- (2012) Dong Ho Woo et al. CELL
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Peephole into the Brain: Neuropathological Features of Alzheimer’s Disease Revealed by in vivo Two-Photon Imaging
- (2012) Sabine Liebscher et al. Frontiers in Psychiatry
- Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy
- (2011) Johanna L. Crimins et al. ACTA NEUROPATHOLOGICA
- Amyloid-Dependent and Amyloid-Independent Stages of Alzheimer Disease
- (2011) Bradley T. Hyman ARCHIVES OF NEUROLOGY
- Soluble A Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors
- (2011) S. Li et al. JOURNAL OF NEUROSCIENCE
- Robust Central Reduction of Amyloid- in Humans with an Orally Available, Non-Peptidic -Secretase Inhibitor
- (2011) P. C. May et al. JOURNAL OF NEUROSCIENCE
- Alzheimer's disease: synapses gone cold
- (2011) Robert M Koffie et al. Molecular Neurodegeneration
- Genome-wide association study of Alzheimer's disease with psychotic symptoms
- (2011) P Hollingworth et al. MOLECULAR PSYCHIATRY
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
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- (2010) Gyungah Jun ARCHIVES OF NEUROLOGY
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- (2010) Lars M. Ittner et al. CELL
- Excitability and Synaptic Communication within the Oligodendrocyte Lineage
- (2010) L. M. De Biase et al. JOURNAL OF NEUROSCIENCE
- Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein
- (2010) J. A. Harris et al. JOURNAL OF NEUROSCIENCE
- Long-term potentiation depends on release of d-serine from astrocytes
- (2010) Christian Henneberger et al. NATURE
- Aβ oligomers inhibit synapse remodelling necessary for memory consolidation
- (2010) Darragh B. Freir et al. NEUROBIOLOGY OF AGING
- Astrocytes in Alzheimer’s disease
- (2010) Alexei Verkhratsky et al. Neurotherapeutics
- Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice
- (2010) Tobias Bittner et al. PLoS One
- Channel-Mediated Tonic GABA Release from Glia
- (2010) S. Lee et al. SCIENCE
- Preparation of Mouse Brain Tissue for Immunoelectron Microscopy
- (2010) Marie-Éve Tremblay et al. Jove-Journal of Visualized Experiments
- Neuron-glia synapses in the brain
- (2009) Dwight E. Bergles et al. BRAIN RESEARCH REVIEWS
- A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice
- (2009) M. Meyer-Luehmann et al. JOURNAL OF NEUROSCIENCE
- -Secretase Inhibition Reduces Spine Density In Vivo via an Amyloid Precursor Protein-Dependent Pathway
- (2009) T. Bittner et al. JOURNAL OF NEUROSCIENCE
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life
- (2009) Ganesh M. Shankar et al. NEUROBIOLOGY OF DISEASE
- Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
- (2009) Shaomin Li et al. NEURON
- Oligomeric amyloid associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
- (2009) R. M. Koffie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
- (2009) K. V. Kuchibhotla et al. SCIENCE
- Tau pathophysiology in neurodegeneration: a tangled issue
- (2009) Tara L. Spires-Jones et al. TRENDS IN NEUROSCIENCES
- Molecular dissection of reactive astrogliosis and glial scar formation
- (2009) Michael V. Sofroniew TRENDS IN NEUROSCIENCES
- Environmental enrichment enhances cellular plasticity in transgenic mice with Alzheimer-like pathology
- (2008) Arne Herring et al. EXPERIMENTAL NEUROLOGY
- Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance
- (2008) T. Bolmont et al. JOURNAL OF NEUROSCIENCE
- Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
- (2008) Melanie Meyer-Luehmann et al. NATURE
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
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