Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner

Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Stephen C. Cunnane et al.   JOURNAL OF ALZHEIMERS DISEASE

Interaction of plasmenylcholine with free radicals in selected model systems

(2017) A. Broniec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

(2017) Stuart G. Snowden et al.   PLOS MEDICINE

Shotgun lipidomics in substantiating lipid peroxidation in redox biology: Methods and applications

(2017) Changfeng Hu et al.   Redox Biology

Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers

(2016) Tomohiro Umeda et al.   BRAIN

Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry-What, how and why?

(2016) Miao Wang et al.   MASS SPECTROMETRY REVIEWS

Lipidomics for studying metabolism

(2016) Xianlin Han   Nature Reviews Endocrinology

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease

(2016) Timothy A. Couttas et al.   NEUROBIOLOGY OF AGING

Cognitive deficits in single App knock-in mouse models

(2016) Akira Masuda et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Increased iPLA2 activity and levels of phosphorylated GSK3B in platelets are associated with donepezil treatment in Alzheimer’s disease patients

(2015) L. L. Talib et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model

(2015) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

(2015) Frances K. Wiseman et al.   NATURE REVIEWS NEUROSCIENCE

MALDI-TOF MS Imaging of Metabolites with a N-(1-Naphthyl) Ethylenediamine Dihydrochloride Matrix and Its Application to Colorectal Cancer Liver Metastasis

(2014) Jianing Wang et al.   ANALYTICAL CHEMISTRY

Cytosolic phospholipase A2protein as a novel therapeutic target for spinal cord injury

(2014) Nai-Kui Liu et al.   ANNALS OF NEUROLOGY

Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis

(2013) Hua Cheng et al.   JOURNAL OF NEUROCHEMISTRY

The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux

(2013) Sachiko Nomura et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Lysophospholipids: Their Generation, Physiological Role and Detection. Are They Important Disease Markers?

(2012) Beate Fuchs et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease

(2011) Robin B. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer's disease: synapses gone cold

(2011) Robert M Koffie et al.   Molecular Neurodegeneration

Phospholipase A2 and arachidonic acid in Alzheimer's disease

(2010) Rene O. Sanchez-Mejia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Mouse Model of Amyloid   Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo

(2010) T. Tomiyama et al.   JOURNAL OF NEUROSCIENCE

Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series

(2010) Daniel McNaughton et al.   NEUROBIOLOGY OF AGING

Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease

(2010) De-Cai Wang et al.   NEUROBIOLOGY OF AGING

The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

(2009) Kazuchika Nishitsuji et al.   AMERICAN JOURNAL OF PATHOLOGY

Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics

(2009) Kui Yang et al.   ANALYTICAL CHEMISTRY

Cerebrospinal Fluid Secretory Ca2+-Dependent Phospholipase A2 Activity Is Increased in Alzheimer Disease

(2009) S. Chalbot et al.   CLINICAL CHEMISTRY

Amyloid-β E22Δ variant induces synaptic alteration in mouse hippocampal slices

(2009) Hiroshi Takuma et al.   NEUROREPORT

Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations

(2008) Ibrahim Malik et al.   AMERICAN JOURNAL OF PATHOLOGY

A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

(2008) Takami Tomiyama et al.   ANNALS OF NEUROLOGY

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION

Analyses of Group III Secreted Phospholipase A2Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis

(2008) Hiroyasu Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of cytosolic phospholipase A2 α by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages

(2008) Dawn E. Tucker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The emerging role of group VI calcium-independent phospholipase A2in releasing docosahexaenoic acid from brain phospholipids: Fig. 1.

(2008) Joshua T. Green et al.   JOURNAL OF LIPID RESEARCH

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2in cortical neurons

(2008) Phullara B. Shelat et al.   JOURNAL OF NEUROCHEMISTRY

Neuroaxonal Dystrophy Caused by Group VIA Phospholipase A2 Deficiency in Mice: A Model of Human Neurodegenerative Disease

(2008) K. Shinzawa et al.   JOURNAL OF NEUROSCIENCE

Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

(2008) J S Rao et al.   MOLECULAR PSYCHIATRY

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

(2008) Rene O Sanchez-Mejia et al.   NATURE NEUROSCIENCE

Neurodegeneration associated with genetic defects in phospholipase A2

(2008) A. Gregory et al.   NEUROLOGY

Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics

(2008) Xianlin Han et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Arachidonic acid induces both Na+and Ca2+entry resulting in apoptosis

(2007) Kwang-Ming Fang et al.   JOURNAL OF NEUROCHEMISTRY