Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation

(2017) Yan-Chu Chen et al.   Frontiers in Molecular Neuroscience

Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches

(2016) Parveen Salahuddin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques

(2015) Hye Yun Kim et al.   Nature Communications

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation

(2015) Miguel Angel Burguillos et al.   Cell Reports

R47H Variant ofTREM2Associated With Alzheimer Disease in a Large Late-Onset Family

(2015) Olena Korvatska et al.   JAMA Neurology

Extracellular Galectin-3 in Tumor Progression and Metastasis

(2014) Anneliese Fortuna-Costa et al.   Frontiers in Oncology

Aβ42-Binding Peptoids as Amyloid Aggregation Inhibitors and Detection Ligands

(2013) Yuan Luo et al.   ACS Chemical Neuroscience

Elevated Galectin-3 Levels in the Serum of Patients With Alzheimer's Disease

(2013) Xuexin Wang et al.   American Journal of Alzheimers Disease and Other Dementias

The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-  Oligomer Toxicity

(2013) V. G. Ostapchenko et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of Transthyretin Inhibition of  -Amyloid Aggregation In Vitro

(2013) X. Li et al.   JOURNAL OF NEUROSCIENCE

The case for soluble Aβ oligomers as a drug target in Alzheimer's disease

(2013) Franz Hefti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

(2012) Marcus Fändrich   JOURNAL OF MOLECULAR BIOLOGY

Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model

(2012) J. Brouillette et al.   JOURNAL OF NEUROSCIENCE

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer’s disease?

(2011) Natalia N. Nalivaeva et al.   JOURNAL OF NEUROCHEMISTRY

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid  -peptides in human cerebrospinal fluid

(2011) A. Halim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectins: regulators of acute and chronic inflammation

(2010) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

Brain-Derived Neurotrophic Factor Enhances Bcl-xL Expression Through Protein Kinase Casein Kinase 2-Activated and Nuclear Factor Kappa B-Mediated Pathway in Rat Hippocampus

(2010) Chih C. Chao et al.   BRAIN PATHOLOGY

Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning

(2010) Derek J C Tai et al.   EMBO JOURNAL

Galectin-3 secreted by human umbilical cord blood-derived mesenchymal stem cells reduces amyloid-β42 neurotoxicity in vitro

(2010) Ju-Yeon Kim et al.   FEBS LETTERS

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

(2010) Qicheng Zhao et al.   Molecular Cancer

Neprilysin and Amyloid Beta Peptide Degradation

(2008) Louis Hersh et al.   Current Alzheimer Research