Targeting Notch4 in Cancer: Molecular Mechanisms and Therapeutic Perspectives
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Notch4 in Cancer: Molecular Mechanisms and Therapeutic Perspectives
Authors
Keywords
-
Journal
Cancer Management and Research
Volume Volume 13, Issue -, Pages 7033-7045
Publisher
Informa UK Limited
Online
2021-09-08
DOI
10.2147/cmar.s315511
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Regulation of Notch signaling by E3 ubiquitin ligases
- (2021) Debdeep Dutta et al. FEBS Journal
- The Role of DLLs in Cancer: A Novel Therapeutic Target
- (2020) Meng-Xi Xiu et al. OncoTargets and Therapy
- P2Y2R has a significant correlation with Notch‑4 in patients with breast cancer
- (2020) Dong Kim et al. Oncology Letters
- Frequent Activation of Notch Signaling Pathway in Colorectal Cancers and Its Implication in Patient Survival Outcome
- (2020) Jilani Purusottapatnam Shaik et al. Journal of Oncology
- The oncogenic role of Jagged1/Notch signaling in cancer
- (2020) Meng-xi Xiu et al. BIOMEDICINE & PHARMACOTHERAPY
- Notch1 in Cancer Therapy: Possible Clinical Implications and Challenges
- (2020) L. Gharaibeh et al. MOLECULAR PHARMACOLOGY
- Sharing the initial experience of pan-cancer panel analysis in high-risk renal cell carcinoma in the Korean population
- (2020) Jungyo Suh et al. BMC Urology
- DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation
- (2020) Jiazhe Liu et al. CELL CYCLE
- More Insights on the Use of γ‐Secretase Inhibitors in Cancer Treatment
- (2020) Pilar López‐Nieva et al. ONCOLOGIST
- DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy
- (2019) Daniel S. Peiffer et al. CANCER RESEARCH
- Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma
- (2019) Allen S. Ho et al. JOURNAL OF CLINICAL INVESTIGATION
- The clinicopathological and genetic features of ovarian diffuse large B-cell lymphoma
- (2019) Hui Xu et al. PATHOLOGY
- All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia
- (2019) Chi Huu Nguyen et al. Cell Death & Disease
- Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines
- (2018) L. Gelsomino et al. CANCER LETTERS
- NOTCH4 regulates colorectal cancer proliferation, invasiveness, and determines clinical outcome of patients
- (2018) Zixi Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Alterations of Notch pathway in patients with adenoid cystic carcinoma of the trachea and its impact on survival
- (2018) Mian Xie et al. LUNG CANCER
- The Role ofNotch3in Cancer
- (2018) Zviadi Aburjania et al. ONCOLOGIST
- NOTCH4 Is a Novel Prognostic Marker that Correlates with Colorectal Cancer Progression and Prognosis
- (2018) Guiyang Wu et al. Journal of Cancer
- Identifying Circulating Tumor DNA Mutation Profiles in Metastatic Breast Cancer Patients with Multiline Resistance
- (2018) Zhe-Yu Hu et al. EBioMedicine
- Inhibition of Notch signaling enhances chemosensitivity in B cell precursor acute lymphoblastic leukemia.
- (2018) Paul Takam Kamga et al. CANCER RESEARCH
- Preliminary exploration of potential molecular therapeutic targets in recurrent and metastatic parathyroid carcinomas
- (2018) Ming Cui et al. INTERNATIONAL JOURNAL OF CANCER
- Evaluation of the correlation of vasculogenic mimicry, Notch4, DLL4, and KAI1/CD82 in the prediction of metastasis and prognosis in non-small cell lung cancer
- (2018) Yichao Wang et al. MEDICINE
- Notch Signaling in Development, Tissue Homeostasis, and Disease
- (2017) Chris Siebel et al. PHYSIOLOGICAL REVIEWS
- Prognostic roles of Notch receptor mRNA expression in human ovarian cancer
- (2017) Chuan Chen et al. Oncotarget
- MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma
- (2016) Chartia Ching-Mei Cheung et al. BMC CANCER
- Notch4+ cancer stem-like cells promote the metastatic and invasive ability of melanoma
- (2016) Xian Lin et al. CANCER SCIENCE
- Exploring miRNA based approaches in cancer diagnostics and therapeutics
- (2016) Shivangi Mishra et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Association of Notch4 with metastasis in human oral squamous cell carcinoma
- (2016) Harishankar MK et al. LIFE SCIENCES
- The Clinical Significance of miR-34a in Pancreatic Ductal Carcinoma and Associated Molecular and Cellular Mechanisms
- (2016) Li-Min Long et al. PATHOBIOLOGY
- Translational significance of Nodal, Cripto-1 and Notch4 in adult nevi
- (2016) Luigi Strizzi et al. Oncology Letters
- Notch4 inhibition reduces migration and invasion and enhances sensitivity to docetaxel by inhibiting Akt/fascin in pancreatic cancer cells
- (2016) Cui-Juan Qian et al. Oncology Letters
- Prognostic values of four Notch receptor mRNA expression in gastric cancer
- (2016) Xiaoyu Wu et al. Scientific Reports
- Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1
- (2015) A.-R. Pedrosa et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate
- (2015) Su-Hyeong Kim et al. BREAST CANCER RESEARCH AND TREATMENT
- Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells
- (2015) Shambhavi Naik et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Notch Reporter Activity in Breast Cancer Cell Lines Identifies a Subset of Cells with Stem Cell Activity
- (2015) R. C. D'Angelo et al. MOLECULAR CANCER THERAPEUTICS
- The vascular delta-like ligand-4 (DLL4)-Notch4 signaling correlates with angiogenesis in primary glioblastoma: an immunohistochemical study
- (2015) Jin-feng Zhang et al. TUMOR BIOLOGY
- Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
- (2015) Bruno M. Simões et al. Cell Reports
- Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)
- (2015) Kristen M. Reipas et al. Oncotarget
- Notch4 reveals a novel mechanism regulating Notch signal transduction
- (2014) A.C. James et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- NOTCH1, NOTCH3, NOTCH4, and JAG2 protein levels in human endometrial cancer
- (2014) Aušra Sasnauskienė et al. Medicina-Lithuania
- Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast
- (2013) Alessandra Rustighi et al. EMBO Molecular Medicine
- Notchl and Notch4 are markers for poor prognosis of hepatocellular carcinoma
- (2013) Soomin Ahn et al. Hepatobiliary & Pancreatic Diseases International
- Study of the interaction among Notch pathway receptors, correlation with stemness, as well as their interaction with CD44, dipeptidyl peptidase-IV, hepatocyte growth factor receptor and the SETMAR transferase, in colon cancer stem cells
- (2013) Panagiotis Apostolou et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells
- (2013) J Yun et al. Oncogenesis
- Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo
- (2012) Y. Lombardo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling
- (2012) Yusuke Okubo et al. Nature Communications
- Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy
- (2012) A H Nwabo Kamdje et al. Blood Cancer Journal
- Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells
- (2011) A. H. Nwabo Kamdje et al. BLOOD
- MicroRNA 34c Gene Down-regulation via DNA Methylation Promotes Self-renewal and Epithelial-Mesenchymal Transition in Breast Tumor-initiating Cells
- (2011) Fengyan Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer
- (2010) Tom Donnem et al. CANCER
- Regulation of the Embryonic Morphogen Nodal by Notch4 Facilitates Manifestation of the Aggressive Melanoma Phenotype
- (2010) K. M. Hardy et al. CANCER RESEARCH
- Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor
- (2010) H. Harrison et al. CANCER RESEARCH
- Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis
- (2010) Yutaka Hashimoto et al. CARCINOGENESIS
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment
- (2009) Fabricio F Costa et al. Epigenomics
- A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
- (2008) Y. Funahashi et al. CANCER RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now