Notch4+ cancer stem-like cells promote the metastatic and invasive ability of melanoma

Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors

(2016) Ehsan Bonyadi Rad et al.   CANCER RESEARCH

Stem cell protein Piwil1 endowed endometrial cancer cells with stem-like properties via inducing epithelial-mesenchymal transition

(2015) Zheng Chen et al.   BMC CANCER

Induction of tumor initiation is dependent on CD44s in c-Met+ hepatocellular carcinoma

(2015) Hien Dang et al.   BMC CANCER

New Findings on Breast Cancer Stem Cells: A Review

(2015) Azam Bozorgi et al.   Journal of Breast Cancer

CD24+ Ovarian Cancer Cells Are Enriched for Cancer-Initiating Cells and Dependent on JAK2 Signaling for Growth and Metastasis

(2015) D. Burgos-Ojeda et al.   MOLECULAR CANCER THERAPEUTICS

VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients

(2015) Xiaojuan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish

(2015) Lasse D. Jensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro

(2015) Xu Chen et al.   TUMOR BIOLOGY

Dual effects of collagenase-3 on melanoma: metastasis promotion and disruption of vasculogenic mimicry

(2015) Xiulan Zhao et al.   Oncotarget

Sphere-derived tumor cells exhibit impaired metastasis by a host-mediated quiescent phenotype

(2015) Anne-Marie Bleau et al.   Oncotarget

Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma

(2015) Muly Tham et al.   Oncotarget

Spherical Cancer Models in Tumor Biology

(2015) Louis-Bastien Weiswald et al.   NEOPLASIA

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors

(2015) H. Iwamoto et al.   Science Advances

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma

(2015) Kathleen M. Capaccione et al.   Oncotarget

EGFR Blockade Enriches for Lung Cancer Stem-like Cells through Notch3-Dependent Signaling

(2014) R. R. Arasada et al.   CANCER RESEARCH

Emerging roles of Notch signaling in liver disease

(2014) Fabian Geisler et al.   HEPATOLOGY

The novel panel assay to define tumor-associated antigen-binding antibodies in patients with metastatic melanomas may have diagnostic value

(2014) Beatrix Kotlan et al.   IMMUNOLOGIC RESEARCH

VEGF-targeted cancer therapeutics—paradoxical effects in endocrine organs

(2014) Yihai Cao   Nature Reviews Endocrinology

TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling

(2014) Hong Ji et al.   Nature Communications

ABCG2-Meditated Multidrug Resistance and Tumor-Initiating Capacity of Side Population Cells from Colon Cancer

(2014) Zheng-Yuan Xie et al.   Oncology Research and Treatment

Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres

(2013) Malgorzata Czyz et al.   CANCER BIOLOGY & THERAPY

Cancer Stem–like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production

(2013) Toru Hiraga et al.   CANCER RESEARCH

Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma

(2013) K. A. Hassan et al.   CLINICAL CANCER RESEARCH

Stem cells and targeted approaches to melanoma cure

(2013) George F. Murphy et al.   MOLECULAR ASPECTS OF MEDICINE

Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth

(2013) Xiaojuan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD44 Expressed on Cancer-Associated Fibroblasts Is a Functional Molecule Supporting the Stemness and Drug Resistance of Malignant Cancer Cells in the Tumor Microenvironment

(2013) Yumi Kinugasa et al.   STEM CELLS

Characterization of side population (SP) cells in murine cochlear nucleus

(2012) Hisashi Ooka et al.   ACTA OTO-LARYNGOLOGICA

CD133+ Melanoma Subpopulations Contribute to Perivascular Niche Morphogenesis and Tumorigenicity through Vasculogenic Mimicry

(2012) C.-Y. Lai et al.   CANCER RESEARCH

Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

(2012) L. Asnaghi et al.   CLINICAL CANCER RESEARCH

Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs

(2012) E.-M. E. Hedlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enriching and characterizing cancer stem cell sub-populations in the WM115 melanoma cell line

(2011) Siddarth Chandrasekaran et al.   BIOMATERIALS

Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines

(2011) Lu Cao et al.   BMC GASTROENTEROLOGY

Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function

(2011) Kiran Ramgolam et al.   PLoS One

Regulation of the Embryonic Morphogen Nodal by Notch4 Facilitates Manifestation of the Aggressive Melanoma Phenotype

(2010) K. M. Hardy et al.   CANCER RESEARCH

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation

(2010) S.-H. Chiou et al.   CANCER RESEARCH

Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs

(2010) Mario Cioce et al.   CELL CYCLE

Metastatic potential of tumor-initiating cells in solid tumors

(2010) Amit et al.   Frontiers in Bioscience-Landmark

Notch-1 and Notch-4 Receptors as Prognostic Markers in Breast Cancer

(2010) Katharine Yao et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo

(2010) Lodovica Borghese et al.   STEM CELLS

Expression and functional significance of Twist1 in hepatocellular carcinoma: Its role in vasculogenic mimicry

(2009) Tao Sun et al.   HEPATOLOGY

CD133+ and nestin+ tumor-initiating cells dominate in N29 and N32 experimental gliomas

(2009) Daniel Bexell et al.   INTERNATIONAL JOURNAL OF CANCER