Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway

Gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice

(2020) Kunpeng Wu et al.   BLOOD

Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies

(2020) Amandip Kaur et al.   Journal of Inflammation-London

Effects of Atractylodes Oil on Inflammatory Response and Serum Metabolites in Adjuvant Arthritis Rats

(2020) Qu Linghang et al.   BIOMEDICINE & PHARMACOTHERAPY

Long-Term Consumption of 2-O-β-d-Glucopyranosyl-l-ascorbic Acid from the Fruits of Lycium barbarum Modulates Gut Microbiota in C57BL/6 Mice

(2020) Wei Dong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells

(2020) Ming Liu et al.   Frontiers in Pharmacology

Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases

(2020) Yuge Zhao et al.   Acta Pharmaceutica Sinica B

Anti-colitic effects of Physalin B on dextran sodium sulfate-induced BALB/c mice by suppressing multiple inflammatory signaling pathways

(2020) Qiao Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ulcerative colitis

(2020) Taku Kobayashi et al.   Nature Reviews Disease Primers

Gut Microbiome Changes in Patients with Active Left-Sided Ulcerative Colitis after Fecal Microbiome Transplantation and Topical 5-aminosalicylic Acid Therapy

(2020) Dagmar Schierová et al.   Cells

Dieckol alleviates dextran sulfate sodium‐induced colitis via inhibition of inflammatory pathway and activation of Nrf2/ HO ‐1 signaling pathway

(2020) Xiaoyan Zhu et al.   ENVIRONMENTAL TOXICOLOGY

Paeoniflorin ameliorates experimental colitis by inhibiting gram-positive bacteria-dependent MDP-NOD2 pathway

(2020) Xia Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Changes in intestinal microbiota and correlation with TLRs in ulcerative colitis in the coastal area of northern China

(2020) Ning Xu et al.   MICROBIAL PATHOGENESIS

Malonylation of GAPDH is an inflammatory signal in macrophages

(2019) Silvia Galván-Peña et al.   Nature Communications

Atractylodin Suppresses Dendritic Cell Maturation and Ameliorates Collagen-Induced Arthritis in a Mouse Model

(2019) Cheng Hsuan Chuang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships

(2019) Damian R. Plichta et al.   CELL

Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-κB and MAPK Signaling Pathways

(2019) Mei Jing et al.   Oxidative Medicine and Cellular Longevity

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects

(2019) Shan-Ting Liao et al.   Nature Communications

Deep-Fried Atractylodis Rhizoma Protects against Spleen Deficiency-Induced Diarrhea through Regulating Intestinal Inflammatory Response and Gut Microbiota

(2019) Kun Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Atractylodin attenuates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome and TLR4 pathways

(2018) Fayin Tang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Tight junction proteins in gastrointestinal and liver disease

(2018) Mirjam B Zeisel et al.   GUT

Fight them or feed them: how the intestinal mucus layer manages the gut microbiota

(2018) Bjoern O Schroeder   Gastroenterology Report

New treatment strategies for ulcerative colitis

(2017) Julian Panés et al.   Expert Review of Clinical Immunology

The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis

(2016) V Morampudi et al.   Mucosal Immunology

Carrageenan Gum and Adherent Invasive Escherichia coli in a Piglet Model of Inflammatory Bowel Disease: Impact on Intestinal Mucosa-associated Microbiota

(2016) Peris M. Munyaka et al.   Frontiers in Microbiology

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer

(2015) Weijie Guo et al.   HEPATOLOGY

Systematic Review

(2015) Russell D. Cohen et al.   INFLAMMATORY BOWEL DISEASES

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

(2015) Jan Van den Bossche et al.   Jove-Journal of Visualized Experiments

Signal Transducer and Activator of Transcription 3 - A Promising Target in Colitis-Associated Cancer

(2014) Ashok Kumar Pandurangan et al.   Asian Pacific Journal of Cancer Prevention

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

(2014) Liangchun Yang et al.   Nature Communications

The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNF 

(2014) M. P. Smith et al.   Cancer Discovery

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

(2014) Alexander A Shestov et al.   eLife

Adverse Events of Tumor Necrosis Factor Inhibitors

(2013) Klaus Fellermann   DIGESTIVE DISEASES

Gut Microbial Flora, Prebiotics, and Probiotics in IBD: Their Current Usage and Utility

(2013) Franco Scaldaferri et al.   Biomed Research International

Efficacy of 5-Aminosalicylates in Ulcerative Colitis: Systematic Review and Meta-Analysis

(2011) Alexander C Ford et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme

(2011) Chao Peng et al.   MOLECULAR & CELLULAR PROTEOMICS

Epithelial: Lamina Propria Lymphocyte Interactions Promote Epithelial Cell Differentiation

(2007) Stephanie Dahan et al.   GASTROENTEROLOGY