Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells

The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway

(2020) Yuming Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways

(2020) Tingwen Zhou et al.   PHYTOTHERAPY RESEARCH

Insulin promotes invasion and migration of KRASG12D mutant HPNE cells by upregulating MMP-2 gelatinolytic activity via ERK- and PI3K-dependent signalling

(2019) Guangfu Wang et al.   CELL PROLIFERATION

Nobiletin exhibits potent inhibition on tumor necrosis factor alpha‐induced calcification of human aortic valve interstitial cells via targeting ABCG2 and AKR1B1

(2019) Kang Xu et al.   PHYTOTHERAPY RESEARCH

Effects of Bakuchiol on chondrocyte proliferation via the PI3K‐Akt and ERK1/2 pathways mediated by the estrogen receptor for promotion of the regeneration of knee articular cartilage defects

(2019) Kang Xu et al.   CELL PROLIFERATION

Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve

(2019) Yuming Huang et al.   Stem Cells International

Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway

(2018) Kang Xu et al.   Frontiers in Pharmacology

Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models

(2017) Jiarui Nie et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The shift of macrophages toward M1 phenotype promotes aortic valvular calcification

(2017) Geng Li et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

(2017) Hai-Jian Sun et al.   Cell Death & Disease

Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification

(2017) Arkady Rutkovskiy et al.   Journal of the American Heart Association

NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes

(2015) Sorina Georgiana Boaru et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calcification in Aortic Stenosis

(2015) Tania A. Pawade et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions

(2014) Mai F. Tolba et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Aortic stenosis and coronary artery disease: What do we know? What don't we know? A comprehensive review of the literature with proposed treatment algorithms

(2014) J.-M. Paradis et al.   EUROPEAN HEART JOURNAL

The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops

(2012) Chen Li et al.   CARDIOVASCULAR PATHOLOGY

Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer

(2011) Jing Wu et al.   CANCER LETTERS

Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification

(2011) Sophie E.P. New et al.   CIRCULATION RESEARCH

Imaging of the Aortic Valve Using Fluorodeoxyglucose Positron Emission Tomography

(2011) Gergana Marincheva-Savcheva et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats

(2008) Sefa Celik et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY