Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-κB and MAPK Signaling Pathways

Andrographolide sulfonate improves Alzheimer-associated phenotypes and mitochondrial dysfunction in APP/PS1 transgenic mice

(2018) Ji Geng et al.   BIOMEDICINE & PHARMACOTHERAPY

Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression

(2016) Weicheng Wang et al.   BIOCHEMICAL PHARMACOLOGY

Protective effects of andrographolide derivative AL-1 on high glucose-induced oxidative stress in RIN-m cells

(2016) Hui Yan et al.   CURRENT PHARMACEUTICAL DESIGN

MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation

(2016) Wen Liu et al.   Oncotarget

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

(2016) Shuang Peng et al.   Oncotarget

Atorvastatin attenuates TNBS-induced rat colitis: the involvement of the TLR4/NF-kB signaling pathway

(2016) Amir Rashidian et al.   INFLAMMOPHARMACOLOGY

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways

(2016) Shuang Peng et al.   Acta Pharmaceutica Sinica B

Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways

(2016) Yali Yang et al.   Scientific Reports

Andrographolide derivative AL-1 improves insulin resistance through down-regulation of NF-κB signalling pathway

(2015) Yongmei Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation

(2015) Wenjie Guo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Multiple protective mechanisms of alpha-lipoic acid in oxidation, apoptosis and inflammation against hydrogen peroxide induced toxicity in human lymphocytes

(2015) Mahban Rahimifard et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies

(2015) Sahil Gambhir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice

(2015) Zhengjiang Qian et al.   Scientific Reports

Depletion of Apoptosis Signal-Regulating Kinase 1 Prevents Bile Duct Ligation–Induced Necroinflammation and Subsequent Peribiliary Fibrosis

(2014) Hirotsugu Noguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

(2014) Wenjie Guo et al.   Autophagy

Anti-inflammatory Effects of Baicalin, Baicalein, and Wogonin In Vitro and In Vivo

(2014) Wonhwa Lee et al.   INFLAMMATION

Alpha-Lipoic Acid Exerts Anti-Inflammatory Effects on Lipopolysaccharide-Stimulated Rat Mesangial Cells via Inhibition of Nuclear Factor Kappa B (NF-κB) Signaling Pathway

(2014) Guofu Li et al.   INFLAMMATION

Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation

(2014) Wei Dou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibitory Effects of Palmultang on Inflammatory Mediator Production Related to Suppression of NF-κB and MAPK Pathways and Induction of HO-1 Expression in Macrophages

(2014) You-Chang Oh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases

(2014) H. Ali et al.   JOURNAL OF CONTROLLED RELEASE

Anti-inflammatory effect of Phellinus linteus grown on germinated brown rice on dextran sodium sulfate-induced acute colitis in mice and LPS-activated macrophages

(2014) Minjung Song et al.   JOURNAL OF ETHNOPHARMACOLOGY

Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways

(2014) Susana Sánchez-Fidalgo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Ethanol Extract ofAntrodia camphorataGrown on Germinated Brown Rice Suppresses Inflammatory Responses in Mice with Acute DSS-Induced Colitis

(2013) Dong Ki Park et al.   Evidence-based Complementary and Alternative Medicine

Anti-Inflammatory Effect of Procyanidins from Wild Grape (Vitis amurensis) Seeds in LPS-Induced RAW 264.7 Cells

(2013) Min-Ji Bak et al.   Oxidative Medicine and Cellular Longevity

Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis

(2012) William J Sandborn et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Evaluation of Fecal Myeloperoxidase as a Biomarker of Disease Activity and Severity in Ulcerative Colitis

(2012) Ibrahim Masoodi et al.   DIGESTIVE DISEASES AND SCIENCES

APicrorhiza kurroaDerivative, Picroliv, Attenuates the Development of Dextran-Sulfate-Sodium-Induced Colitis in Mice

(2012) De-Kui Zhang et al.   MEDIATORS OF INFLAMMATION

A novel andrographolide derivative AL-1 exerts its cytotoxicity on K562 cells through a ROS-dependent mechanism

(2012) Yong-Yang Zhu et al.   PROTEOMICS

Evaluation of P38 MAPK Pathway as a Molecular Signature in Ulcerative Colitis

(2011) Xinmei Zhao et al.   JOURNAL OF PROTEOME RESEARCH

PPARα contributes to colonic protection in mice with DSS-induced colitis

(2010) Yasu-Taka Azuma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Andrographolide: A Review of its Anti-inflammatory Activity via Inhibition of NF-kappaB Activation from Computational Chemistry Aspects

(2010) Jutti Levita et al.   International Journal of Pharmacology

Amelioration of murine dextran sulfate sodium-induced colitis by nuclear factor-κb decoy oligonucleotides

(2008) Jun Ying Xiang et al.   AMERICAN JOURNAL OF SURGERY

Synthesis and evaluation of antibacterial activities of andrographolide analogues

(2008) Xiaojian Jiang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY