Paeoniflorin ameliorates experimental colitis by inhibiting gram-positive bacteria-dependent MDP-NOD2 pathway

Targeting NF-κB pathway for treating ulcerative colitis: comprehensive regulatory characteristics of Chinese medicines

(2020) Peng-De Lu et al.   Chinese Medicine

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

(2019) Zhenxing Huang et al.   Nature Microbiology

The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6′-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases

(2019) Jiajie Tu et al.   Frontiers in Pharmacology

Connexin 26 and 43 play a role in regulating proinflammatory events in the epidermis

(2019) Laura García-Vega et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases

(2019) Yen-Chih Wang et al.   ACS Chemical Biology

Across-shift changes in upper airways after exposure to bacterial cell wall components

(2019) Marcin Cyprowski et al.   ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE

Environmental Risk Factors for Inflammatory Bowel Diseases: an Umbrella Review of Meta-analyses

(2019) Daniele Piovani et al.   GASTROENTEROLOGY

Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain

(2019) Danli Zhou et al.   Journal of Neuroinflammation

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD

(2019) Anaïs Larabi et al.   Autophagy

Dysregulation of Intestinal Epithelial Cell RIPK Pathways Promotes Chronic Inflammation in the IBD Gut

(2019) Ricard Garcia-Carbonell et al.   Frontiers in Immunology

Paeoniflorin Prevents Intestinal Barrier Disruption and Inhibits Lipopolysaccharide (LPS)-Induced Inflammation in Caco-2 Cell Monolayers

(2019) Xi-Xi Wu et al.   INFLAMMATION

Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy

(2019) Jin Wen et al.   PHARMACOLOGICAL RESEARCH

Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice

(2019) Keyvan Amirshahrokhi   INTERNATIONAL IMMUNOPHARMACOLOGY

Secoisolariciresinol diglucoside suppresses Dextran sulfate sodium salt-induced colitis through inhibiting NLRP1 inflammasome

(2019) Zhen Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

RIP2 filament formation is required for NOD2 dependent NF-κB signalling

(2018) Erika Pellegrini et al.   Nature Communications

The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease

(2018) Tao Zuo et al.   Frontiers in Microbiology

Gut mucosal-associated microbiota better discloses Inflammatory Bowel Disease differential patterns than faecal microbiota

(2018) Annamaria Altomare et al.   DIGESTIVE AND LIVER DISEASE

Emergent Behavior of IBD-Associated Escherichia coli During Disease

(2018) Michael John Renouf et al.   INFLAMMATORY BOWEL DISEASES

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

(2018) Arnau Vich Vila et al.   Science Translational Medicine

Protective effects of paeoniflorin on TNBS-induced ulcerative colitis through inhibiting NF-kappaB pathway and apoptosis in mice

(2017) Peiqing Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ulcerative colitis

(2017) Ryan Ungaro et al.   LANCET

Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis

(2017) Derrick D Eichele et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Nucleotide-Binding Oligomerization Domain 2 Contributes to Limiting Growth of Mycobacterium abscessus in the Lung of Mice by Regulating Cytokines and Nitric Oxide Production

(2017) Jun-Young Lee et al.   Frontiers in Immunology

Intestinal Bacteria Composition and Translocation of Bacteria in Inflammatory Bowel Disease

(2017) Spyros Vrakas et al.   PLoS One

Transcription Factor NF-κB: An Update on Intervention Strategies

(2016) Arvind Panday et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology

(2016) Dylan K. McDaniel et al.   INFLAMMATORY BOWEL DISEASES

Poncirin and its metabolite ponciretin attenuate colitis in mice by inhibiting LPS binding on TLR4 of macrophages and correcting Th17/Treg imbalance

(2016) Geum-Dan Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

NOD2-RIP2–Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis

(2016) Manuela S. L. Nascimento et al.   JOURNAL OF INFECTIOUS DISEASES

Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces

(2016) Loubna Abdel Hadi et al.   MEDIATORS OF INFLAMMATION

Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases

(2016) Caroline Meyer Olesen et al.   PHARMACOLOGY & THERAPEUTICS

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Nucleotide-binding oligomerization domain-2 (NOD2) regulates type-1 cytokine responses to Mycobacterium avium but is not required for host control of infection

(2015) Natália B. Carvalho et al.   MICROBES AND INFECTION

Paeoniflorin attenuates hepatic ischemia/reperfusion injury via anti-oxidative, anti-inflammatory and anti-apoptotic pathways

(2015) YE TAO et al.   Experimental and Therapeutic Medicine

Sulfasalazine Attenuates Staphylococcal Enterotoxin B-Induced Immune Responses

(2015) Teresa Krakauer   Toxins

Commensal Gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization

(2014) Y Nakanishi et al.   Mucosal Immunology

Functions of NOD-Like Receptors in Human Diseases

(2013) Yifei Zhong et al.   Frontiers in Immunology

Muramyl dipeptide responsive pathways in Crohn’s disease: from NOD2 and beyond

(2012) Mohammad Salem et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options

(2011) Giuseppe Pignataro et al.   CURRENT OPINION IN PHARMACOLOGY

The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

(2011) Guillaume Dalmasso et al.   GASTROENTEROLOGY

Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases

(2011) Warren Strober et al.   GASTROENTEROLOGY

Induction of RIP-2 kinase by proinflammatory cytokines is mediated via NF-κB signaling pathways and involves a novel feed-forward regulatory mechanism

(2009) Xixi Yin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Drug-induced liver injury: Is it somehow foreseeable?

(2009) Giovanni Tarantino et al.   WORLD JOURNAL OF GASTROENTEROLOGY