The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis

Using Corticosteroids to Reshape the Gut Microbiome

(2015) Edmond Y. Huang et al.   INFLAMMATORY BOWEL DISEASES

Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation

(2015) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses

(2014) Ganive Bhinder et al.   INFECTION AND IMMUNITY

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

(2013) Sohini Mukherjee et al.   NATURE

SIGIRR, a Negative Regulator of TLR/IL-1R Signalling Promotes Microbiota Dependent Resistance to Colonization by Enteric Bacterial Pathogens

(2013) Ho Pan Sham et al.   PLoS Pathogens

Healing of intestinal inflammation by IL-22

(2012) Atsushi Mizoguchi   INFLAMMATORY BOWEL DISEASES

The Bactericidal Activity of the C-type Lectin RegIIIβ against Gram-negative Bacteria involves Binding to Lipid A

(2012) Tsuyoshi Miki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mucin Muc2 Deficiency and Weaning Influences the Expression of the Innate Defense Genes Reg3β, Reg3γ and Angiogenin-4

(2012) Nanda Burger-van Paassen et al.   PLoS One

INTERLEUKIN-22 MODULATES GUT EPITHELIAL AND IMMUNE BARRIER FUNCTIONS FOLLOWING ACUTE ALCOHOL EXPOSURE AND BURN INJURY

(2012) Juan L. Rendon et al.   SHOCK

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis Model

(2010) Malin E. V. Johansson et al.   PLoS One

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine

(2009) Petra Louis et al.   FEMS MICROBIOLOGY LETTERS

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteomic Analyses of the Two Mucus Layers of the Colon Barrier Reveal That Their Main Component, the Muc2 Mucin, Is Strongly Bound to the Fcgbp Protein

(2009) Malin E. V. Johansson et al.   JOURNAL OF PROTEOME RESEARCH

Mucosal bacterial microflora and mucus layer thickness inadolescents with inflammatory bowel disease

(2009) Krzysztof Fyderek et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Resistin-like molecule β regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice

(2008) Rim Belharbi Krimi et al.   INFLAMMATORY BOWEL DISEASES