Mass Production of Virus-Like Particles Using Chloroplast Genetic Engineering for Highly Immunogenic Oral Vaccine Against Fish Disease

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

(2021) Saghi Nooraei et al.   JOURNAL OF NANOBIOTECHNOLOGY

COVID-19 Crisis: How Can Plant Biotechnology Help?

(2021) Md. Jahidul Islam Shohag et al.   Plants-Basel

Current status and future directions of fish vaccines employing virus-like particles

(2020) Ki-Ho Jeong et al.   FISH & SHELLFISH IMMUNOLOGY

Betanodavirus and VER Disease: A 30-year Research Review

(2020) Isabel Bandín et al.   Pathogens

Aquaculture at the crossroads of global warming and antimicrobial resistance

(2020) Miriam Reverter et al.   Nature Communications

The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be

(2020) Daniel Tusé et al.   Frontiers in Plant Science

Plant-Based Drugs and Vaccines for COVID-19

(2020) Nasir Mahmood et al.   Vaccines

Synthetic biology for bioengineering virus-like particle vaccines

(2019) Hayley K. Charlton Hume et al.   BIOTECHNOLOGY AND BIOENGINEERING

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

(2019) Edward P. Rybicki   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Plant-Made Nervous Necrosis Virus-Like Particles Protect Fish Against Disease

(2019) Johanna Marsian et al.   Frontiers in Plant Science

Review on Immersion Vaccines for Fish: An Update 2019

(2019) Jarl Bøgwald et al.   Microorganisms

Stability of virus-like particles of red-spotted grouper nervous necrosis virus in the aqueous state, and the vaccine potential of lyophilized particles

(2018) Nguyen Thi Lan et al.   BIOLOGICALS

Plastid transformation and its application in metabolic engineering

(2018) Paulina Fuentes et al.   CURRENT OPINION IN BIOTECHNOLOGY

Oral immunization with recombinant protein antigen expressed in tobacco against fish nervous necrosis virus

(2018) Ho Seong CHO et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Oral immunization with cell-free self-assembly virus-like particles against orange-spotted grouper nervous necrosis virus in grouper larvae, Epinephelus coioides

(2018) Ming-Hui Chien et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Cold chain and virus-free oral polio booster vaccine made in lettuce chloroplasts confers protection against all three poliovirus serotypes

(2018) Henry Daniell et al.   PLANT BIOTECHNOLOGY JOURNAL

A Ycf2-FtsHi heteromeric AAA-ATPase complex is required for chloroplast protein import

(2018) Shingo Kikuchi et al.   PLANT CELL

Betanodavirus : Dissection of the viral life cycle

(2017) C-F Low et al.   JOURNAL OF FISH DISEASES

Oral vaccination through voluntary consumption of the convict grouper Epinephelus septemfasciatus with yeast producing the capsid protein of red-spotted grouper nervous necrosis virus

(2017) Seo Young Cho et al.   VETERINARY MICROBIOLOGY

High-level expression of thermostable cellulolytic enzymes in tobacco transplastomic plants and their use in hydrolysis of an industrially pretreated Arundo donax L. biomass

(2016) Daniela Castiglia et al.   Biotechnology for Biofuels

Molecular pharming — VLPs made in plants

(2016) Johanna Marsian et al.   CURRENT OPINION IN BIOTECHNOLOGY

Immunity to nervous necrosis virus infections of orange-spotted grouper ( Epinephelus coioides ) by vaccination with virus-like particles

(2016) Kebing Lin et al.   FISH & SHELLFISH IMMUNOLOGY

Understanding the interaction between Betanodavirus and its host for the development of prophylactic measures for viral encephalopathy and retinopathy

(2016) Janina Z. Costa et al.   FISH & SHELLFISH IMMUNOLOGY

Pathogenicity of Striped Jack Nervous Necrosis Virus (SJNNV) Isolated from Asymptomatic Wild Japanese Jack Mackerel Trachurus japonicus

(2016) Toyohiro Nishioka et al.   FISH PATHOLOGY

Plant-based oral vaccines against zoonotic and non-zoonotic diseases

(2016) Naila Shahid et al.   PLANT BIOTECHNOLOGY JOURNAL

Plant-produced biopharmaceuticals: A case of technical developments driving clinical deployment

(2016) G. P. Lomonossoff et al.   SCIENCE

Infectious Diseases Affect Marine Fisheries and Aquaculture Economics

(2015) Kevin D. Lafferty et al.   Annual Review of Marine Science

The Engineered Chloroplast Genome Just Got Smarter

(2015) Shuangxia Jin et al.   TRENDS IN PLANT SCIENCE

Protective immunity against nervous necrosis virus in convict grouper Epinephelus septemfasciatus following vaccination with virus-like particles produced in yeast Saccharomyces cerevisiae

(2015) Ga Ram Wi et al.   VETERINARY MICROBIOLOGY

Transgenic plants: a 5-year update on oral antipathogen vaccine development

(2014) Marisela Hernández et al.   Expert Review of Vaccines

Immune gene expressions in grouper larvae (Epinephelus coioides) induced by bath and oral vaccinations with inactivated betanodavirus

(2014) Yu-Hsuan Kai et al.   FISH & SHELLFISH IMMUNOLOGY

Overproduction of Hyperthermostable β-1,4-Endoglucanase from the ArchaeonPyrococcus horikoshiiby Tobacco Chloroplast Engineering

(2013) Yoichi NAKAHIRA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Bioengineering virus-like particles as vaccines

(2013) Linda H.L. Lua et al.   BIOTECHNOLOGY AND BIOENGINEERING

How can plant genetic engineering contribute to cost-effective fish vaccine development for promoting sustainable aquaculture?

(2013) Jihong Liu Clarke et al.   PLANT MOLECULAR BIOLOGY

Low Cost Tuberculosis Vaccine Antigens in Capsules: Expression in Chloroplasts, Bio-Encapsulation, Stability and Functional Evaluation In Vitro

(2013) Priya Saikumar Lakshmi et al.   PLoS One

Immune responses of orange-spotted grouper, Epinephelus coioides, against virus-like particles of betanodavirus produced in Escherichia coli

(2013) Yu-Xiong Lai et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

A chloroplast-derivedToxoplasma gondiiGRA4 antigen used as an oral vaccine protects against toxoplasmosis in mice

(2012) María del L. Yácono et al.   PLANT BIOTECHNOLOGY JOURNAL

Staphylococcus aureus Efb protein expression in Nicotiana tabacum and immune response to oral administration

(2012) Margherita Festa et al.   RESEARCH IN VETERINARY SCIENCE

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

Expression of dengue-3 premembrane and envelope polyprotein in lettuce chloroplasts

(2011) Anderson Paul Kanagaraj et al.   PLANT MOLECULAR BIOLOGY

Virus-like particles: potential veterinary vaccine immunogens

(2011) Fuxiao Liu et al.   RESEARCH IN VETERINARY SCIENCE

Chloroplasts as expression platforms for plant-produced vaccines

(2010) Teodoro Cardi et al.   Expert Review of Vaccines

Transplastomic expression of a modified human papillomavirus L1 protein leading to the assembly of capsomeres in tobacco: a step towards cost-effective second-generation vaccines

(2010) M. Tahir Waheed et al.   TRANSGENIC RESEARCH

Recovery of nicotine-free proteins from tobacco leaves using phosphate buffer system under controlled conditions

(2009) H. Fu et al.   BIORESOURCE TECHNOLOGY

Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery

(2009) Abdoreza Davoodi-Semiromi et al.   PLANT BIOTECHNOLOGY JOURNAL

Effective Plague Vaccination via Oral Delivery of Plant Cells Expressing F1-V Antigens in Chloroplasts

(2008) P. A. Arlen et al.   INFECTION AND IMMUNITY

Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic

(2008) Alicia Fernández-San Millán et al.   PLANT BIOTECHNOLOGY JOURNAL

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic

(2008) Melanie Oey et al.   PLANT JOURNAL

Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco

(2008) Paolo Lenzi et al.   TRANSGENIC RESEARCH