Plant-Based Drugs and Vaccines for COVID-19

Molecular farming – The slope of enlightenment

(2020) Rainer Fischer et al.   BIOTECHNOLOGY ADVANCES

Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs

(2020) Hui Luo et al.   Chinese Journal of Integrative Medicine

Ethnobotanical Description and Biological Activities of Senna alata

(2020) Oluwole Solomon Oladeji et al.   Evidence-based Complementary and Alternative Medicine

Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists

(2020) Lila Bouadma et al.   INTENSIVE CARE MEDICINE

Coronavirus Infections—More Than Just the Common Cold

(2020) Catharine I. Paules et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China

(2020) Min Wei et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Development and Clinical Application of A Rapid IgM‐IgG Combined Antibody Test for SARS‐CoV‐2 Infection Diagnosis

(2020) Zhengtu Li et al.   JOURNAL OF MEDICAL VIROLOGY

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A novel coronavirus outbreak of global health concern

(2020) Chen Wang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus Emerging in China — Key Questions for Impact Assessment

(2020) Vincent J. Munster et al.   NEW ENGLAND JOURNAL OF MEDICINE

Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam

(2020) Lan T. Phan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission

(2020) Xintian Xu et al.   Science China-Life Sciences

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19

(2020) Valentino Clemente et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

(2020) Chenguang Shen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Compassionate Use of Remdesivir for Patients with Severe Covid-19

(2020) Jonathan Grein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness of convalescent plasma therapy in severe COVID-19 patients

(2020) Kai Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential Applications of Plant Biotechnology against SARS-CoV-2

(2020) Teresa Capell et al.   TRENDS IN PLANT SCIENCE

Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study

(2020) Qingxian Cai et al.   Engineering

What Does Plant-Based Vaccine Technology Offer to the Fight against COVID-19?

(2020) Sergio Rosales-Mendoza et al.   Vaccines

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

(2020) Young Hun Chung et al.   ADVANCED DRUG DELIVERY REVIEWS

Antiviral Effects of Plant-Derived Essential Oils and Their Components: An Updated Review

(2020) Li Ma et al.   MOLECULES

A review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19)

(2020) Fangfang Huang et al.   PHARMACOLOGICAL RESEARCH

Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)

(2020) Li Runfeng et al.   PHARMACOLOGICAL RESEARCH

Natural product-derived phytochemicals as potential agents against coronaviruses: A review

(2020) Janice S. Mani et al.   VIRUS RESEARCH

From Farm to Finger Prick—A Perspective on How Plants Can Help in the Fight Against COVID-19

(2020) Karen A. McDonald et al.   Frontiers in Bioengineering and Biotechnology

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

(2020) Christian Bailly et al.   PHARMACOLOGY & THERAPEUTICS

Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus

(2020) K. Chojnacka et al.   Journal of Functional Foods

Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana

(2020) Kaewta Rattanapisit et al.   Scientific Reports

The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be

(2020) Daniel Tusé et al.   Frontiers in Plant Science

Biomimetic Virus-Like Particles as Severe Acute Respiratory Syndrome Coronavirus 2 Diagnostic Tools

(2020) Soo Khim Chan et al.   ACS Nano

Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review

(2019) Vahid Soleimani et al.   PHYTOTHERAPY RESEARCH

Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults

(2019) Stéphane Pillet et al.   PLoS One

Built‐In Active Microneedle Patch with Enhanced Autonomous Drug Delivery

(2019) Miguel Angel Lopez‐Ramirez et al.   ADVANCED MATERIALS

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics

(2019) Sabue Mulangu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience

(2018) Jae-Hoon Ko et al.   ANTIVIRAL THERAPY

Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats

(2018) Dan Hu et al.   Emerging Microbes & Infections

Essential oil composition, total phenolic, flavonoid contents, and antioxidant activity of Thymus species collected from different regions of Iran

(2017) Behnaz Tohidi et al.   FOOD CHEMISTRY

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

(2017) Yousuke FURUTA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

(2017) Wei Zhang et al.   PLoS Pathogens

Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)—Sierra Leone, 2014

(2016) Chang-Qing Bai et al.   CLINICAL INFECTIOUS DISEASES

Transient plant transformation mediated by Agrobacterium tumefaciens: Principles, methods and applications

(2015) Pavel Krenek et al.   BIOTECHNOLOGY ADVANCES

The proteome of the infectious bronchitis virus Beau-R virion

(2015) Stuart D. Dent et al.   JOURNAL OF GENERAL VIROLOGY

The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis

(2014) John Mair-Jenkins et al.   JOURNAL OF INFECTIOUS DISEASES

Taliglucerase alfa: An enzyme replacement therapy using plant cell expression technology

(2014) Gregory A. Grabowski et al.   MOLECULAR GENETICS AND METABOLISM

Algae-based oral recombinant vaccines

(2014) Elizabeth A. Specht et al.   Frontiers in Microbiology

Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava

(2013) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

(2012) P. C. Y. Woo et al.   JOURNAL OF VIROLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic Strategies

(2012) Chloé Geller et al.   Viruses-Basel

Plant-made pharmaceuticals: Leading products and production platforms

(2011) Matthew Paul et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Convalescent Plasma Treatment Reduced Mortality in Patients With Severe Pandemic Influenza A (H1N1) 2009 Virus Infection

(2011) I. F. Hung et al.   CLINICAL INFECTIOUS DISEASES

Species diversity, usages, molecular markers and barcode of medicinal Senna species (Fabaceae, Caesalpinioideae) in Thailand

(2011) Pansa Monkheang   Journal of Medicinal Plants Research

Biflavonoids from Torreya nucifera displaying SARS-CoV 3CLpro inhibition

(2010) Young Bae Ryu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Senna alata

(2009) Thierry Hennebelle et al.   FITOTERAPIA

Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication

(2008) Chung-Jen Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY