Cold chain and virus-free oral polio booster vaccine made in lettuce chloroplasts confers protection against all three poliovirus serotypes

Resource Needs for the Trivalent Oral Polio to Bivalent Oral Polio Vaccine Switch in Indonesia

(2017) Marionette Holmes et al.   JOURNAL OF INFECTIOUS DISEASES

Implementing the Synchronized Global Switch from Trivalent to Bivalent Oral Polio Vaccines—Lessons Learned From the Global Perspective

(2017) Alejandro Ramirez Gonzalez et al.   JOURNAL OF INFECTIOUS DISEASES

Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

(2017) Roland W. Herzog et al.   MOLECULAR THERAPY

Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice

(2017) Kwang-Chul Kwon et al.   PLANT BIOTECHNOLOGY JOURNAL

Responding to a cVDPV1 outbreak in Ukraine: Implications, challenges and opportunities

(2017) Nino Khetsuriani et al.   VACCINE

Long-term evaluation of mucosal and systemic immunity and protection conferred by different polio booster vaccines

(2017) Yuhong Xiao et al.   VACCINE

Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine

(2017) Johanna Marsian et al.   Nature Communications

Progress Toward Containment of Poliovirus Type 2 — Worldwide, 2017

(2017) Nicoletta Previsani et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Update on Vaccine-Derived Polioviruses — Worldwide, January 2016–June 2017

(2017) Jaume Jorba et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Vaccination via Chloroplast Genetics: Affordable Protein Drugs for the Prevention and Treatment of Inherited or Infectious Human Diseases

(2016) Henry Daniell et al.   Annual Review of Genetics

Low cost delivery of proteins bioencapsulated in plant cells to human non-immune or immune modulatory cells

(2016) Yuhong Xiao et al.   BIOMATERIALS

Modeling the spread of polio in an IPV-vaccinated population: lessons learned from the 2013 silent outbreak in southern Israel

(2016) Rami Yaari et al.   BMC Medicine

Molecular pharming — VLPs made in plants

(2016) Johanna Marsian et al.   CURRENT OPINION IN BIOTECHNOLOGY

Is introduction of IPV “Good news for billions of children”?

(2016) Stine Byberg et al.   LANCET INFECTIOUS DISEASES

Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells

(2016) Kwang-Chul Kwon et al.   MOLECULAR THERAPY

Cold chain and virus-free chloroplast-made booster vaccine to confer immunity against different poliovirus serotypes

(2016) Hui-Ting Chan et al.   PLANT BIOTECHNOLOGY JOURNAL

Codon Optimization to Enhance Expression Yields Insights into Chloroplast Translation

(2016) Kwang-Chul Kwon et al.   PLANT PHYSIOLOGY

Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array

(2016) Nolan C. Worstell et al.   PLoS One

Low cost industrial production of coagulation factor IX bioencapsulated in lettuce cells for oral tolerance induction in hemophilia B

(2015) Jin Su et al.   BIOMATERIALS

Immunological adjuvant effect of the peptide fraction from the larvae of Musca domestica

(2015) Liqing Chen et al.   BMC Complementary and Alternative Medicine

The Effect of Oral Polio Vaccine at Birth on Infant Mortality: A Randomized Trial

(2015) Najaaraq Lund et al.   CLINICAL INFECTIOUS DISEASES

Low-cost oral delivery of protein drugs bioencapsulated in plant cells

(2015) Kwang-Chul Kwon et al.   PLANT BIOTECHNOLOGY JOURNAL

Activation of human mast cells by retrocyclin and protegrin highlight their immunomodulatory and antimicrobial properties

(2015) Kshitij Gupta et al.   Oncotarget

Cholera Toxin B: One Subunit with Many Pharmaceutical Applications

(2015) Keegan Baldauf et al.   Toxins

Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells

(2014) A. Sherman et al.   BLOOD

Low Cost Tuberculosis Vaccine Antigens in Capsules: Expression in Chloroplasts, Bio-Encapsulation, Stability and Functional Evaluation In Vitro

(2013) Priya Saikumar Lakshmi et al.   PLoS One

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

Systematic Review of Mucosal Immunity Induced by Oral and Inactivated Poliovirus Vaccines against Virus Shedding following Oral Poliovirus Challenge

(2012) Thomas R. Hird et al.   PLoS Pathogens

Expression of dengue-3 premembrane and envelope polyprotein in lettuce chloroplasts

(2011) Anderson Paul Kanagaraj et al.   PLANT MOLECULAR BIOLOGY

Virus-like particles in vaccine development

(2010) António Roldão et al.   Expert Review of Vaccines

Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide

(2010) Diane Boyhan et al.   PLANT BIOTECHNOLOGY JOURNAL

The Role of Heterologous Chloroplast Sequence Elements in Transgene Integration and Expression

(2010) T. Ruhlman et al.   PLANT PHYSIOLOGY

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice

(2010) D. Verma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transplastomic expression of a modified human papillomavirus L1 protein leading to the assembly of capsomeres in tobacco: a step towards cost-effective second-generation vaccines

(2010) M. Tahir Waheed et al.   TRANSGENIC RESEARCH

Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery

(2009) Abdoreza Davoodi-Semiromi et al.   PLANT BIOTECHNOLOGY JOURNAL

Vaccine-derived poliovirus (VDPV): Impact on poliomyelitis eradication

(2009) Philip Minor   VACCINE

Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco

(2008) Paolo Lenzi et al.   TRANSGENIC RESEARCH

Need for polio boosters after age two years

(2008) Margaret B. Rennels   VACCINE